Drug Information

Drug General Information
Drug ID
D0V3LD
Former ID
DIB016983
Drug Name
DIO-901
Synonyms
CAM-4044; VLD glucagon (diabetes), DiObex; Very low dose glucagon (diabetes), DiObex; VLD glucagon (FluidCrystal, diabetes), DiObex; VLD glucagon (extended-release, diabetes) DiObex
Indication Type 1 diabetes [ICD9: 250; ICD10:E10] Terminated [548146]
Company
DiObex
Target and Pathway
Target(s) Glucagon receptor Target Info Agonist [525683]
KEGG Pathway Neuroactive ligand-receptor interaction
Glucagon signaling pathway
Reactome Glucagon signaling in metabolic regulation
G alpha (q) signalling events
G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 548146Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022421)
Ref 525683Effects of low-dose and high-dose glucagon on glucose production and gluconeogenesis in humans. Metabolism. 2000 Jan;49(1):39-46.

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