Drug Information

Drug General Information
Drug ID
D0U9LV
Former ID
DIB014045
Drug Name
LY-2428757
Synonyms
GLP-PEG, Eli Lilly; GLP1-PEG, Eli Lilly
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Phase 2 [522514]
Company
Eli Lilly & Co
Target and Pathway
Target(s) Glucagon-like peptide 1 receptor Target Info Stimulator [544122]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Reactome Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 522514ClinicalTrials.gov (NCT00804986) A Study for Patients With Type 2 Diabetes Mellitus. U.S. National Institutes of Health.
Ref 544122Role and development of GLP-1 receptor agonists in the management of diabetes. Diabetes Metab Syndr Obes. 2009; 2: 37-49.

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