Drug Information

Drug General Information
Drug ID
D0G9LP
Former ID
DIB014177
Drug Name
Neutralase
Synonyms
Heparinase I, IBEX
Indication Angiogenesis disorder [ICD10:I00-I99] Discontinued in Phase 3 [546338]
Company
IBEX Technologies Inc
CAS Number
CAS 9025-39-2
Target and Pathway
Target(s) Heparanase Target Info Modulator [528014]
KEGG Pathway Glycosaminoglycan degradation
Metabolic pathways
Proteoglycans in cancer
Pathway Interaction Database Syndecan-1-mediated signaling events
Reactome HS-GAG degradation
WikiPathways Glycosaminoglycan metabolism
References
Ref 546338Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007559)
Ref 528014Heparanase neutralizes the anticoagulation properties of heparin and low-molecular-weight heparin. J Thromb Haemost. 2006 Mar;4(3):560-5.

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