Drug Information

Drug General Information
Drug ID
D04ICR
Former ID
DIB005370
Drug Name
Second-generation leptin
Synonyms
Leptin B; Leptin C; A-100; A-200; Second-generation leptin analogs, Amgen
Indication Obesity [ICD9: 278; ICD10:E66] Terminated [547353]
Company
Rockefeller University
Target and Pathway
Target(s) Leptin receptor Target Info Modulator [544044]
KEGG Pathway Cytokine-cytokine receptor interaction
Neuroactive ligand-receptor interaction
AMPK signaling pathway
Jak-STAT signaling pathway
Adipocytokine signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Pathway Interaction Database Signaling events mediated by PTP1B
WikiPathways Leptin signaling pathway
AMPK Signaling
References
Ref 547353Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015436)
Ref 544044Effects of Exogenous Leptin on Satiety and Satiation in Patients with Lipodystrophy and Leptin Insufficiency. J Clin Endocrinol Metab. 2004 September; 89(9): 4258-4263.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.