Drug Information

Drug General Information
Drug ID
D0D2JD
Former ID
DIB008888
Drug Name
TH-0318
Synonyms
ThGLP-1, Theratechnologies; LAP-stabilized GLP-1 analogs (diabetes), Theratechnologies/OctoPlus
Indication Diabetes [ICD9: 253.5, 588.1; ICD10:E23.2, N25.1] Terminated [547615]
Company
Theratechnologies
Target and Pathway
Target(s) Glucagon-like peptide 1 receptor Target Info Modulator [543638]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Reactome Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 547615Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017892)
Ref 543638(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 249).

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