TTD | Drug: D0Q8DM

Drug General Information
Drug ID	D0Q8DM
Former ID	DIB008014
Drug Name	BIM-26226
Synonyms	D-Pentafluorophenylalanyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valyl-D-alanyl-L-histidyl-L-leucine methyl ester; (D-Pentafluorophenylalanyl6,D-alanyl11)bombesin (6-13) methyl ester
Indication	Cancer [ICD9: 140-229; ICD10:C00-C96]		Discontinued in Phase 1	[545685]
Structure		Download 2D MOL
CAS Number	CAS 136207-23-3
Target and Pathway
Target(s)	Gastrin-releasing peptide receptor	Target Info	Modulator	[534659]
KEGG Pathway	Calcium signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCRs, Other
References
Ref 545685	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004166)
Ref 534659	Effect of the gastrin-releasing peptide antagonist BIM 26226 and lanreotide on an acinar pancreatic carcinoma. Eur J Pharmacol. 1998 Apr 17;347(1):77-86.

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Drug Information