Drug Information

Drug General Information
Drug ID
D01REE
Former ID
DIB003839
Drug Name
DA-3031
Synonyms
Long-acting agent (neutropenia), Dong-A; PEG-GCSF (neutropenia), Dong-A; PEG-granulocyte colony stimulating factor (neutropenia),Dong-A
Drug Type
Small molecular drug
Indication Neutropenia [ICD9: 288; ICD10:D70] Phase 3 [524038]
Company
Dong-A Pharmaceutical Co Ltd
Structure
Download
2D MOL

3D MOL
Formula
C10H19NO2
Canonical SMILES
CC(=C)C(=O)OCCN(C)C.C=C
InChI
1S/C8H15NO2.C2H4/c1-7(2)8(10)11-6-5-9(3)4;1-2/h1,5-6H2,2-4H3;1-2H2
InChIKey
PNMYDOBPCBCQIA-UHFFFAOYSA-N
PubChem Compound ID
168302
PubChem Substance ID
46241675, 74995883, 113462817, 126672128, 135124233, 162756188, 223665892
Target and Pathway
Target(s) Granulocyte colony-stimulating factor Target Info Modulator [532495]
KEGG Pathway Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
Malaria
NetPath Pathway IL1 Signaling Pathway
TNFalpha Signaling Pathway
TCR Signaling Pathway
WikiPathways Cytokines and Inflammatory Response
Hematopoietic Stem Cell Differentiation
References
Ref 524038ClinicalTrials.gov (NCT01674855) Phase III Study of DA-3031(PEG-G-CSF) in Chemotherapy-induced Neutropenia. U.S. National Institutes of Health.
Ref 532495Relationship between absolute neutrophil count profiles and pharmacokinetics of DA-3031, a pegylated granulocyte colony-stimulating factor (pegylated-G-CSF): a dose block-randomized, double-blind, dose-escalation study in healthy subjects. Clin Drug Investig. 2013 Nov;33(11):817-24.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.