Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0UZ4G
|
||||
| Former ID |
DIB006435
|
||||
| Drug Name |
99mTc-rBitistatin
|
||||
| Indication | Embolism [ICD10:I74, I82] | Phase 1/2 | [522520] | ||
| Company |
Temple University
|
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| Target and Pathway | |||||
| Target(s) | Glycoprotein IIb/IIIa receptor | Target Info | Modulator | [529086] | |
| Reactome | Platelet degranulation | ||||
| Elastic fibre formation | |||||
| PECAM1 interactions | |||||
| Molecules associated with elastic fibres | |||||
| Integrin cell surface interactions | |||||
| Syndecan interactions | |||||
| ECM proteoglycans | |||||
| Integrin alphaIIb beta3 signaling | |||||
| GRB2:SOS provides linkage to MAPK signaling for Integrins | |||||
| p130Cas linkage to MAPK signaling for integrins | |||||
| VEGFA-VEGFR2 Pathway | |||||
| MAP2K and MAPK activation | |||||
| References | |||||
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