Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06EIJ
|
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| Former ID |
DIB004992
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| Drug Name |
RFT-5.dgA
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| Synonyms |
IMTOX-25; Anti-CD25 antibody, University of Texas Southwestern Medical Center; Immunotoxin (cancer), University of Texas Southwestern Medical Center/ Cologne University
|
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| Indication | Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] | Phase 2 | [522307] | ||
| Company |
University of Texas Southwestern Medical Center
|
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| Target and Pathway | |||||
| Target(s) | Interleukin-2 receptor alpha chain | Target Info | Modulator | ||
| PANTHER Pathway | Interleukin signaling pathway | ||||
| Pathway Interaction Database | IL12-mediated signaling events | ||||
| Calcineurin-regulated NFAT-dependent transcription in lymphocytes | |||||
| Arf6 trafficking events | |||||
| SHP2 signaling | |||||
| IL2-mediated signaling events | |||||
| IL2 signaling events mediated by PI3K | |||||
| IL2 signaling events mediated by STAT5 | |||||
| Calcium signaling in the CD4+ TCR pathway | |||||
| Downstream signaling in naï | |||||
| IL12 signaling mediated by STAT4 | |||||
| References | |||||
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