Drug Information

Drug General Information
Drug ID
D02CFV
Former ID
DIB005424
Drug Name
Solubilized type 1 native bovine collagen
Synonyms
ARG-201; Solubilized type 1 native bovine collagen (oral, scleroderma); Solubilized type 1 native bovine collagen (oral, scleroderma), arGentis/University of Tennessee
Indication Scleroderma [ICD9: 701.0710.1; ICD10:L94.0-L94.1, M34] Phase 2 [548602]
Company
University of Tennessee
Target and Pathway
Target(s) Collagen I Target Info Modulator
KEGG Pathway PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Platelet activation
Protein digestion and absorption
Amoebiasis
PathWhiz Pathway Coagulation
Reactome GPVI-mediated activation cascade
Collagen degradation
Collagen biosynthesis and modifying enzymes
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Assembly of collagen fibrils and other multimeric structures
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Anchoring fibril formation
Syndecan interactions
Non-integrin membrane-ECM interactions
ECM proteoglycans
Scavenging by Class A Receptors
Platelet Adhesion to exposed collagen
WikiPathways Senescence and Autophagy in Cancer
Inflammatory Response Pathway
Osteoblast Signaling
Focal Adhesion
Assembly of collagen fibrils and other multimeric structures
Binding and Uptake of Ligands by Scavenger Receptors
Collagen biosynthesis and modifying enzymes
Nanoparticle-mediated activation of receptor signaling
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in epithelium - TarBase
References
Ref 548602Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026882)

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