Drug General Information
Drug ID
D08BBL
Former ID
DNCL003462
Drug Name
Iomab-B
Synonyms
Iomab-B (TN)
Drug Type
Antibody
Indication Acute myeloid leukemia [ICD9: 205; ICD10:C92.0] Phase 2 [546963]
Company
Actinium Pharmaceuticals
Target and Pathway
Target(s) Leukocyte common antigen Target Info [550198]
KEGG Pathway Cell adhesion molecules (CAMs)
T cell receptor signaling pathway
Fc gamma R-mediated phagocytosis
Primary immunodeficiency
NetPath Pathway TCR Signaling Pathway
IL2 Signaling Pathway
PANTHER Pathway B cell activation
JAK/STAT signaling pathway
T cell activation
Pathway Interaction Database BCR signaling pathway
TCR signaling in na&#xef
TCR signaling in na&#xef
CXCR4-mediated signaling events
Reactome Phosphorylation of CD3 and TCR zeta chains
Other semaphorin interactions
WikiPathways Interferon type I signaling pathways
EPO Receptor Signaling
B Cell Receptor Signaling Pathway
TCR signaling
Semaphorin interactions
References
Ref 546963Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011613)
Ref 550198Clinical pipeline report, company report or official report of Actinium Pharmaceuticals.

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