Drug Information

Drug General Information
Drug ID
D0M4RX
Former ID
DNCL002915
Drug Name
RG7685
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Discontinued in Phase 2 [549037]
Company
Roche
Target and Pathway
Target(s) Glucagon-like peptide 1 receptor Target Info Modulator
Gastric inhibitory polypeptide receptor Target Info Modulator
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretionhsa04024:cAMP signaling pathway
Reactome Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
G alpha (s) signalling events
Glucagon-type ligand receptorsR-HSA-418555:G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signalingWP334:GPCRs, Class B Secretin-like
GPCR downstream signaling
References
Ref 549037Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031660)

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