Drug Information

Drug General Information
Drug ID
D0Y1BF
Former ID
DIB003364
Drug Name
APG-201
Synonyms
Protein-based apoptosis sensitizer (cancer), Apogenix
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Investigative [543460]
Company
Apogenix Biotechnology AG
Target and Pathway
Target(s) Interleukin-4 receptor alpha chain Target Info Antagonist [543460]
KEGG Pathway Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
Inflammatory bowel disease (IBD)
NetPath Pathway IL2 Signaling Pathway
IL4 Signaling Pathway
EGFR1 Signaling Pathway
PANTHER Pathway Interleukin signaling pathway
Pathway Interaction Database p73 transcription factor network
IL4-mediated signaling events
WikiPathways Inflammatory Response Pathway
IL-4 Signaling Pathway
References
Ref 543460(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1697).
Ref 543460(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1697).

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