Drug Information

Drug General Information
Drug ID
D08XVR
Former ID
DIB002694
Drug Name
Baminercept
Synonyms
BG-9924; Soluble lymphotoxin beta receptor, Biogen; Soluble lymphotoxin beta receptor, Biogen Idec
Indication Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] Phase 2 [523833]
Company
Biogen Idec
CAS Number
CAS 909110-25-4
Target and Pathway
Target(s) Lymphotoxin beta receptor Target Info Antagonist [523833]
KEGG Pathway Cytokine-cytokine receptor interaction
NF-kappa B signaling pathway
HIF-1 signaling pathway
Intestinal immune network for IgA production
HTLV-I infection
Viral carcinogenesis
Reactome TNFR2 non-canonical NF-kB pathway
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
References
Ref 523833ClinicalTrials.gov (NCT01552681) Baminercept in Sj??ren's Syndrome. U.S. National Institutes of Health.
Ref 523833ClinicalTrials.gov (NCT01552681) Baminercept in Sj??ren's Syndrome. U.S. National Institutes of Health.

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