Drug Information

Drug General Information
Drug ID
D07OED
Former ID
DIB004336
Drug Name
BL-5040
Synonyms
Leptin antagonist (anorexia), BioLineRx; Leptin antagonist (cachexia), BioLineRx; Leptin antagonist (inflammatory bowel disease), BioLineRx
Indication Cachexia [ICD9: 799.4; ICD10:R64] Investigative [543464]
Company
Hebrew University of Jerusalem
Target and Pathway
Target(s) Leptin receptor Target Info Antagonist [543464]
KEGG Pathway Cytokine-cytokine receptor interaction
Neuroactive ligand-receptor interaction
AMPK signaling pathway
Jak-STAT signaling pathway
Adipocytokine signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Pathway Interaction Database Signaling events mediated by PTP1B
WikiPathways Leptin signaling pathway
AMPK Signaling
References
Ref 543464(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1712).
Ref 543464(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1712).

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