Drug Information

Drug General Information
Drug ID
D03OYY
Former ID
DIB016384
Drug Name
MAR-531
Synonyms
MAR-531; Glucagon analogs (injector pen, hypoglycemia); Glucagon analogs (injector pen, hypoglycemia), Marcadia/ Eli Lilly
Indication Hypoglycemia [ICD9: 250.8, 251.0, 251.1, 251.2, 270.3, 775.6, 962.3; ICD10:E16.0-E16.2] Investigative [543641]
Company
Marcadia Biotech Inc
Target and Pathway
Target(s) Glucagon receptor Target Info Modulator [543641]
KEGG Pathway Neuroactive ligand-receptor interaction
Glucagon signaling pathway
Reactome Glucagon signaling in metabolic regulation
G alpha (q) signalling events
G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 543641(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 251).
Ref 543641(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 251).

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