Drug General Information
Drug ID
D00TTS
Former ID
DIB010923
Drug Name
Human chorionic gonadotropin
Synonyms
Human chorionic gonadotropin (heart disease); HCG (heart disease), Stem Cell Therapeutics; Human chorionic gonadotropin (heart disease), Stem Cell Therapeutics
Indication Heart disease [ICD9: 390-429; ICD10:I00-I52] Terminated [538686], [546721]
Company
Stem Cell Therapeutics Corp
Target and Pathway
Target(s) Lutropin-choriogonadotropic hormone receptor Target Info Inhibitor [543644]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Ovarian steroidogenesis
Prolactin signaling pathway
NetPath Pathway FSH Signaling Pathway
Pathway Interaction Database Arf6 signaling events
PathWhiz Pathway Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin
Reactome Hormone ligand-binding receptors
G alpha (s) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Ovarian Infertility Genes
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 538686(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1160).
Ref 546721Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009926)
Ref 543644(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 254).

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