Drug Information

Drug General Information
Drug ID
D0B5JV
Former ID
DIB006952
Drug Name
Labeled LH superagonist
Synonyms
Labeled LH superagonist (breast/prostrate/ovarian cancers); Labeled LH superagonist (breast/prostrate/ovarian cancers), Trophogen; Labeled luteinizing hormone superagonist (breast/prostrate/ovarian cancers), Trophogen
Indication Breast cancer [ICD9: 174, 175; ICD10:C50] Investigative [543644]
Company
Trophogen Inc
Target and Pathway
Target(s) Lutropin-choriogonadotropic hormone receptor Target Info Agonist [543644]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Ovarian steroidogenesis
Prolactin signaling pathway
NetPath Pathway FSH Signaling Pathway
Pathway Interaction Database Arf6 signaling events
PathWhiz Pathway Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin
Reactome Hormone ligand-binding receptors
G alpha (s) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Ovarian Infertility Genes
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 543644(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 254).
Ref 543644(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 254).

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