Drug General Information
Drug ID
D0D2GZ
Former ID
DIB000481
Drug Name
AL-408
Synonyms
AL-108 analog (neurodegenerative diseases), Allon
Indication Central nervous system disease [ICD10:G00-G99] Investigative [531616]
Company
Allon Therapeutics Inc
Structure
Download
2D MOL

3D MOL

Canonical SMILES
N1(C(=O)[C@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@@H]2N(C(<br />=O)[C@H](NC(=O)[C@@H](CC(=O)N)N)C)CCC2)C(C)C)CO)[C@@H](<br />CC)C)[C@@H](C(=O)N[C@@H](C(=O)O)CCC(=O)N)CCC1
Target and Pathway
Target(s) Microtubule-associated protein tau Target Info Modulator [531616]
KEGG Pathway MAPK signaling pathway
Alzheimer's disease
NetPath Pathway IL2 Signaling Pathway
EGFR1 Signaling Pathway
Pathway Interaction Database LPA receptor mediated events
Reelin signaling pathway
Reactome Caspase-mediated cleavage of cytoskeletal proteins
WikiPathways Notch Signaling Pathway
IL-2 Signaling Pathway
MAPK Signaling Pathway
Copper homeostasis
Kit receptor signaling pathway
BDNF signaling pathway
Integrated Pancreatic Cancer Pathway
Alzheimers Disease
Regulation of Microtubule Cytoskeleton
Apoptotic execution phase
IL-5 Signaling Pathway
References
Ref 531616Microtubules (tau) as an emerging therapeutic target: NAP (davunetide). Curr Pharm Des. 2011;17(31):3413-7.
Ref 531616Microtubules (tau) as an emerging therapeutic target: NAP (davunetide). Curr Pharm Des. 2011;17(31):3413-7.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.