Drug Information

Drug General Information
Drug ID
D06KWH
Drug Name
DAB-486-IL-2
Synonyms
153641-26-0; DAB-486-IL-2
Indication Unspecified Investigative [1560018]
Target and Pathway
Target(s) Interleukin-2 receptor subunit beta Target Info Modulator
KEGG Pathway Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Measles
HTLV-I infection
Transcriptional misregulation in cancer
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway Interleukin signaling pathway
Pathway Interaction Database IL12-mediated signaling events
SHP2 signaling
IL2-mediated signaling events
IL2 signaling events mediated by PI3K
IL2 signaling events mediated by STAT5
Downstream signaling in na&#xef
Reactome GPVI-mediated activation cascade
G beta:gamma signalling through PI3Kgamma
Interleukin-2 signaling
RAF/MAP kinase cascade
Interleukin receptor SHC signaling
WikiPathways IL-2 Signaling Pathway
Inflammatory Response Pathway
Interleukin-2 signaling
Interleukin-3, 5 and GM-CSF signaling
References
Ref 1560018Interleukin 2 receptor targeted fusion toxin (DAB486-IL-2) treatment blocks diabetogenic autoimmunity in non-obese diabetic mice.

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