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T59328
Target Info
Target Name Epidermal growth factor receptor (EGFR)
Target type Successful Target
Disease Angina pectoris; HER2/NEU overexpressing breast cancer;
Drugs Amivantamab Drug Info
T68547
Target Info
Target Name Histone deacetylase 1 (HDAC1)
Target type Successful Target
Disease Cutaneous T-cell lymphoma; Breast cancer;
Drugs Panobinostat Drug Info
T08391
Target Info
Target Name Janus kinase 2 (JAK-2)
Target type Successful Target
Disease High-risk myelofibrosis; Rheumatoid arthritis;
Drugs Momelotinib Drug Info
T68251
Target Info
Target Name Matrix metalloproteinase-2 (MMP-2)
Target type Successful Target
Disease Hepatic fibrosis; Acne vulgaris;
Drugs Prinomastat Drug Info
T75243
Target Info
Target Name Serine/threonine-protein kinase mTOR (mTOR)
Target type Successful Target
Disease Artery stenosis; Chronic myelomonocytic leukaemia;
Drugs Temsirolimus Drug Info
T57700
Target Info
Target Name Tyrosine-protein kinase Kit (KIT)
Target type Successful Target
Disease Tenosynovial giant cell tumour; Metastatic colorectal cancer;
Drugs Ripretinib Drug Info
T80975
Target Info
Target Name Vascular endothelial growth factor receptor 2 (KDR)
Target type Successful Target
Disease Metastatic colorectal cancer; Gastrointestinal stromal tumour;
Drugs Tivozanib Drug Info
T99685
Target Info
Target Name HUMAN mammalian target of rapamycin (mTOR)
Target type . Target
Disease Advanced/metastatic breast cancer; Lymphangioleiomyomatosis;
Drugs Sirolimus Drug Info
T92072
Target Info
Target Name Adenosine A1 receptor (ADORA1)
Target type Successful Target
Disease Orthostatic hypotension; Acute and chronic heart failure;
Drugs Caffeine Drug Info
T11211
Target Info
Target Name Androgen receptor (AR)
Target type Successful Target
Disease Acute myeloid leukaemia; Alcoholic hepatitis;
Drugs Clascoterone Drug Info

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