TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T00176	Ubiquitin-protein ligase E3 Mdm2	B26BCK	Varacin	Investigative	179269	C10H13NO2S5	339.6	COC1=C(C2=C(C(=C1)CCN)SSSSS2)OC	IC50 > 295000 nM	Non binder
T00176	Ubiquitin-protein ligase E3 Mdm2	B26ZUC	3-((1-(4-Chlorophenyl)-1-hydroxy-3-oxoisoindolin-2-yl)methyl)pyridine 1-oxide	Investigative	51350252	C20H15ClN2O3	366.8	C1=CC=C2C(=C1)C(=O)N(C2(C3=CC=C(C=C3)Cl)O)CC4=C[N+](=CC=C4)[O-]	IC50 > 200000 nM	Non binder
T00176	Ubiquitin-protein ligase E3 Mdm2	B2UXR8	(3S,6S,9S,12S,15S,18S)-3-Benzyl-6-sec-butyl-15,18-bis(4-hydroxybenzyl)-12-isopropyl-9-methyl-1,4,7,10,13,16-hexaazacyclooctadecane-2,5,8,11,14,17-hexaone	Investigative	52943865	C41H52N6O8	756.9	CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)C)C(C)C)CC2=CC=C(C=C2)O)CC3=CC=C(C=C3)O)CC4=CC=CC=C4	IC50 = 209000 nM	Non binder
T00176	Ubiquitin-protein ligase E3 Mdm2	B3Q7CL	2-((1-(4-Chlorophenyl)-1-hydroxy-3-oxoisoindolin-2-yl)methyl)pyridine-1-oxide	Investigative	51350253	C20H15ClN2O3	366.8	C1=CC=C2C(=C1)C(=O)N(C2(C3=CC=C(C=C3)Cl)O)CC4=CC=CC=[N+]4[O-]	IC50 > 200000 nM	Non binder
T00176	Ubiquitin-protein ligase E3 Mdm2	B7QP8H	3-(4-Chlorophenyl)-3-hydroxy-2-(pyridin-3-ylmethyl)isoindolin-1-one	Investigative	51350118	C20H15ClN2O2	350.8	C1=CC=C2C(=C1)C(=O)N(C2(C3=CC=C(C=C3)Cl)O)CC4=CN=CC=C4	IC50 > 200000 nM	Non binder
T00176	Ubiquitin-protein ligase E3 Mdm2	B7U4YJ	3-(4-Chlorophenyl)-3-[[1-(hydroxymethyl)cyclopropyl]methoxy]-2-[(1-oxidopyridin-1-ium-4-yl)methyl]isoindol-1-one	Investigative	51351257	C25H23ClN2O4	450.9	C1CC1(CO)COC2(C3=CC=CC=C3C(=O)N2CC4=CC=[N+](C=C4)[O-])C5=CC=C(C=C5)Cl	IC50 > 200000 nM	Non binder
T00176	Ubiquitin-protein ligase E3 Mdm2	B9KR4N	3-(4-Chlorophenyl)-3-[[1-(hydroxymethyl)cyclopropyl]methoxy]-2-(pyridin-4-ylmethyl)isoindol-1-one	Investigative	51351129	C25H23ClN2O3	434.9	C1CC1(CO)COC2(C3=CC=CC=C3C(=O)N2CC4=CC=NC=C4)C5=CC=C(C=C5)Cl	IC50 = 252000 nM	Non binder
T00176	Ubiquitin-protein ligase E3 Mdm2	BECO94	4-((1-(4-Chlorophenyl)-1-hydroxy-3-oxoisoindolin-2-yl)methyl)pyridine-1-oxide	Investigative	51350120	C20H15ClN2O3	366.8	C1=CC=C2C(=C1)C(=O)N(C2(C3=CC=C(C=C3)Cl)O)CC4=CC=[N+](C=C4)[O-]	IC50 > 200000 nM	Non binder
T00176	Ubiquitin-protein ligase E3 Mdm2	BHUK64	3-(4-Chlorophenyl)-3-hydroxy-2-(pyridin-2-ylmethyl)isoindolin-1-one	Investigative	51350119	C20H15ClN2O2	350.8	C1=CC=C2C(=C1)C(=O)N(C2(C3=CC=C(C=C3)Cl)O)CC4=CC=CC=N4	IC50 > 200000 nM	Non binder
T00176	Ubiquitin-protein ligase E3 Mdm2	BJ41BU	3-(4-Chlorophenyl)-3-[[1-(hydroxymethyl)cyclopropyl]methoxy]-2-[[4-(trifluoromethyl)phenyl]methyl]isoindol-1-one	Investigative	51351003	C27H23ClF3NO3	501.9	C1CC1(CO)COC2(C3=CC=CC=C3C(=O)N2CC4=CC=C(C=C4)C(F)(F)F)C5=CC=C(C=C5)Cl	IC50 = 214000 nM	Non binder
T00176	Ubiquitin-protein ligase E3 Mdm2	BWN9H2	3-(4-Chlorophenyl)-3-[[1-(hydroxymethyl)cyclopropyl]methoxy]-2-[(1-oxidopyridin-1-ium-3-yl)methyl]isoindol-1-one	Investigative	51351258	C25H23ClN2O4	450.9	C1CC1(CO)COC2(C3=CC=CC=C3C(=O)N2CC4=C[N+](=CC=C4)[O-])C5=CC=C(C=C5)Cl	IC50 > 200000 nM	Non binder