TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T01318 Plasmodium Dihydroorotate dehydrogenase B5GPS8 Ethyl (Z)-2-cyano-3-[(9-ethylcarbazol-3-yl)amino]prop-2-enoate Investigative 16102642 C20H19N3O2 333.4 CCN1C2=C(C=C(C=C2)N/C=C(/C#N)\\C(=O)OCC)C3=CC=CC=C31 IC50 = 32000000000 nM Non binder T01318 Plasmodium Dihydroorotate dehydrogenase BBH80J Diethyl [(dibenzo[b,d]thiophen-2-ylamino)methylidene]propanedioate Investigative 16102641 C20H19NO4S 369.4 CCOC(=O)C(=CNC1=CC2=C(C=C1)SC3=CC=CC=C32)C(=O)OCC IC50 = 5400000000 nM Non binder