TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T02546	Voltage-gated sodium channel alpha Nav1.4	D0UM7O	Ketamine	Approved	3821	C13H16ClNO	237.72	CNC1(CCCCC1=O)C2=CC=CC=C2Cl	IC50 = 800000 nM	Non binder
T02546	Voltage-gated sodium channel alpha Nav1.4	B0HEL5	(2R)-1-Phenoxypropan-2-ol	Investigative	643321	C9H12O2	152.19	C[C@H](COC1=CC=CC=C1)O	EC50 = 208929.61 nM	Non binder
T02546	Voltage-gated sodium channel alpha Nav1.4	B1L5VR	(2R)-N-(2,6-Dimethylphenyl)-N-methylpyrrolidine-2-carboxamide	Investigative	10847196	C14H20N2O	232.32	CC1=C(C(=CC=C1)C)N(C)C(=O)[C@H]2CCCN2	EC50 = 218776.16 nM	Non binder
T02546	Voltage-gated sodium channel alpha Nav1.4	B4OFW2	(R)-2-Amino-N-(2,6-dimethylphenyl)propanamide	Investigative	3080825	C11H16N2O	192.26	CC1=C(C(=CC=C1)C)NC(=O)[C@@H](C)N	EC50 = 275422.87 nM	Non binder
T02546	Voltage-gated sodium channel alpha Nav1.4	B80SCN	(7Ar)-2-(2,6-dimethylphenyl)-5,6,7,7a-tetrahydro-3H-pyrrolo[1,2-c]imidazol-1-one	Investigative	44593027	C14H18N2O	230.31	CC1=C(C(=CC=C1)C)N2CN3CCC[C@@H]3C2=O	EC50 = 501187.23 nM	Non binder
T02546	Voltage-gated sodium channel alpha Nav1.4	B9IDN8	(2R)-N-(2,6-Dimethylphenyl)-N,1-dimethylpyrrolidine-2-carboxamide	Investigative	10634184	C15H22N2O	246.35	CC1=C(C(=CC=C1)C)N(C)C(=O)[C@H]2CCCN2C	EC50 = 501187.23 nM	Non binder
T02546	Voltage-gated sodium channel alpha Nav1.4	BIEX72	Propanamide, 2-amino-N-(2,6-dimethylphenyl)-, (S)-	Investigative	3080827	C11H16N2O	192.26	CC1=C(C(=CC=C1)C)NC(=O)[C@H](C)N	EC50 = 223872.11 nM	Non binder
T02546	Voltage-gated sodium channel alpha Nav1.4	BP2BS1	(S)-1-Phenoxy-2-Propanol	Investigative	6950526	C9H12O2	152.19	C[C@@H](COC1=CC=CC=C1)O	EC50 = 234422.88 nM	Non binder