TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T02719	Metabotropic glutamate receptor 3	B1X8RG	(2R,4R)-4-Amino-1-biphenyl-2-ylmethyl-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302608	C19H20N2O4	340.4	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC=CC=C2C3=CC=CC=C3)C(=O)O	IC50 > 300000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	B2RP7G	4,8-Dicarboxy-6-oxo-undecanedioic acid	Investigative	9861792	C13H18O9	318.28	C(CC(=O)O)C(CC(=O)CC(CCC(=O)O)C(=O)O)C(=O)O	EC50 > 300000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	B48TJE	(2R,4R)-4-Amino-1-(3-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302605	C13H15ClN2O4	298.72	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC(=CC=C2)Cl)C(=O)O	IC50 > 300000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	B54BWE	(2R,4R)-4-Amino-1-naphthalen-2-ylmethyl-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302609	C17H18N2O4	314.34	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC3=CC=CC=C3C=C2)C(=O)O	IC50 > 300000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	BF1ZB7	(2R,4R)-4-Amino-1-(4-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302932	C13H15ClN2O4	298.72	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC=C(C=C2)Cl)C(=O)O	IC50 > 300000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	BGB5T3	(2R,4R)-4-Amino-1-cyclohexylmethyl-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302931	C13H22N2O4	270.32	C1CCC(CC1)CN2C[C@](C[C@@H]2C(=O)O)(C(=O)O)N	IC50 > 300000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	BHS53B	(2R,4R)-4-Amino-1-benzhydrylpyrrolidine-2,4-dicarboxylic acid	Investigative	49799828	C19H20N2O4	340.4	C1[C@@H](N(C[C@]1(C(=O)O)N)C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O	IC50 > 300000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	BO1SZ9	(2R,4R)-4-Amino-1-biphenyl-4-ylmethyl-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302913	C19H20N2O4	340.4	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC=C(C=C2)C3=CC=CC=C3)C(=O)O	IC50 > 300000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	BODA53	(2S,4R)-4-(2,2-Diphenylethylamino-3-oxopropyl)glutamic acid	Investigative	24905650	C22H26N2O5	398.5	C1=CC=C(C=C1)C(CNC(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O)C2=CC=CC=C2	IC50 > 1000000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	BUBT35	(1S,2S)-1-Amino-2-(carboxymethyl)cyclopropane-1-carboxylic acid	Investigative	11768848	C6H9NO4	159.14	C1[C@H]([C@@]1(C(=O)O)N)CC(=O)O	EC50 > 1000000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	BZ07DY	2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid	Investigative	6604795	C8H12N2O4	200.19	CC1=C(C(=O)NO1)CC[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	BZ5HB6	(2R,4R)-4-Amino-1-(2-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302819	C13H15ClN2O4	298.72	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC=CC=C2Cl)C(=O)O	IC50 > 300000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	D09AQK	(R,S)-4-phosphonophenylglycine	Investigative	4545574	C8H10NO5P	231.14	C1=CC(=CC=C1C(C(=O)O)N)P(=O)(O)O	Ki > 200000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	D0N0NJ	1-benzyl-APDC	Investigative	15508178	C13H16N2O4	264.28	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC=CC=C2)C(=O)O	IC50 > 300000 nM	Non binder
T02719	Metabotropic glutamate receptor 3	D0PN6Z	L-AP4	Investigative	179394	C4H10NO5P	183.1	C(CP(=O)(O)O)[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder