TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T05387	Tissue transglutaminase	B2L9WK	(2S)-5-Oxo-2-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]-6-(1,4,5-trimethyl-3-propylimidazol-1-ium-2-yl)sulfanylhexanoic acid;bromide	Investigative	72204902	C32H41BrN4O6S	689.7	CCCN1C(=C([N+](=C1SCC(=O)CC[C@@H](C(=O)O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3)C)C)C.[Br-]	IC50 > 200000 nM	Non binder
T05387	Tissue transglutaminase	B3I6UR	Chembl4166095	Investigative	14977359	C14H11NO3	241.24	C1=CC(=CN=C1)C(=O)/C=C/C2=CC(=C(C=C2)O)O	IC50 = 1001000 nM	Non binder
T05387	Tissue transglutaminase	B3PH7A	1-{4-[(2,3-Dioxo-2,3-dihydro-1H-indol-1-YL)methyl]-2,5-dimethylbenzyl}-1H-indole-2,3-dione	Investigative	3798517	C26H20N2O4	424.4	CC1=CC(=C(C=C1CN2C3=CC=CC=C3C(=O)C2=O)C)CN4C5=CC=CC=C5C(=O)C4=O	IC50 > 250000 nM	Non binder
T05387	Tissue transglutaminase	B63PRD	(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-4-Carbamoyl-2-[(2S)-pyrrolidin-2-ylformamido]butanoyl]pyrrolidin-2-yl]formamido}-3-(2-oxoacetamido)propanamido]-4-methylpentanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanoic acid	Investigative	44437812	C40H57N9O11	839.9	CC(C)C[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O)NC(=O)[C@H](CNC(=O)C=O)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCC(=O)N)NC(=O)[C@@H]4CCCN4	Ki = 300000 nM	Non binder
T05387	Tissue transglutaminase	B6WT0A	(2S)-5-Oxo-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]-6-(1,4,5-trimethyl-3-propylimidazol-1-ium-2-yl)sulfanylhexanoic acid;bromide	Investigative	72204904	C25H35BrN4O6S	599.5	CCCN1C(=C([N+](=C1SCC(=O)CC[C@@H](C(=O)O)NC(=O)CNC(=O)OCC2=CC=CC=C2)C)C)C.[Br-]	IC50 > 200000 nM	Non binder
T05387	Tissue transglutaminase	B7D6YM	Chembl4174015	Investigative	5858472	C14H11NO2	225.24	C1=CC(=CN=C1)C(=O)/C=C/C2=CC=C(C=C2)O	IC50 > 2000000 nM	Non binder
T05387	Tissue transglutaminase	BFXV90	Chembl4169514	Investigative	6179219	C15H13NO3	255.27	COC1=C(C=CC(=C1)/C=C/C(=O)C2=CN=CC=C2)O	IC50 = 688000 nM	Non binder
T05387	Tissue transglutaminase	BHWF31	(E)-3-(3-Hydroxyphenyl)-1-pyridin-3-ylprop-2-en-1-one	Investigative	6020915	C14H11NO2	225.24	C1=CC(=CC(=C1)O)/C=C/C(=O)C2=CN=CC=C2	IC50 = 266000 nM	Non binder
T05387	Tissue transglutaminase	BIM47A	(2S)-6-(1,3-Diethyl-4,5-dimethylimidazol-1-ium-2-yl)sulfanyl-5-oxo-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]hexanoic acid;bromide	Investigative	72204900	C25H35BrN4O6S	599.5	CCN1C(=C([N+](=C1SCC(=O)CC[C@@H](C(=O)O)NC(=O)CNC(=O)OCC2=CC=CC=C2)CC)C)C.[Br-]	IC50 > 200000 nM	Non binder
T05387	Tissue transglutaminase	BJF9A1	(2S)-6-(1,3-Diethyl-4,5-dimethylimidazol-1-ium-2-yl)sulfanyl-5-oxo-2-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]hexanoic acid;bromide	Investigative	72204898	C32H41BrN4O6S	689.7	CCN1C(=C([N+](=C1SCC(=O)CC[C@@H](C(=O)O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3)CC)C)C.[Br-]	IC50 > 200000 nM	Non binder
T05387	Tissue transglutaminase	BLX02C	Chembl4177374	Investigative	8854099	C16H15NO3	269.29	CCOC1=C(C=CC(=C1)/C=C/C(=O)C2=CN=CC=C2)O	IC50 = 484000 nM	Non binder
T05387	Tissue transglutaminase	BM7G0A	(2S)-6-(1-Benzyl-3,4,5-trimethylimidazol-3-ium-2-yl)sulfanyl-5-oxo-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]hexanoic acid;bromide	Investigative	72205087	C29H35BrN4O6S	647.6	CC1=C([N+](=C(N1CC2=CC=CC=C2)SCC(=O)CC[C@@H](C(=O)O)NC(=O)CNC(=O)OCC3=CC=CC=C3)C)C.[Br-]	IC50 > 200000 nM	Non binder
T05387	Tissue transglutaminase	BN0IH2	(2S)-5-Oxo-2-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]-6-(1,4,5-trimethyl-3-phenylimidazol-1-ium-2-yl)sulfanylhexanoic acid;bromide	Investigative	72205081	C35H39BrN4O6S	723.7	CC1=C([N+](=C(N1C2=CC=CC=C2)SCC(=O)CC[C@@H](C(=O)O)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)OCC4=CC=CC=C4)C)C.[Br-]	IC50 > 200000 nM	Non binder
T05387	Tissue transglutaminase	BQ0O5Z	(2S)-6-(1-Benzyl-3,4,5-trimethylimidazol-3-ium-2-yl)sulfanyl-5-oxo-2-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]hexanoic acid;bromide	Investigative	72205085	C36H41BrN4O6S	737.7	CC1=C([N+](=C(N1CC2=CC=CC=C2)SCC(=O)CC[C@@H](C(=O)O)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)OCC4=CC=CC=C4)C)C.[Br-]	IC50 > 200000 nM	Non binder
T05387	Tissue transglutaminase	BV39TU	(2S)-5-Oxo-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]-6-(1,4,5-trimethyl-3-phenylimidazol-1-ium-2-yl)sulfanylhexanoic acid;bromide	Investigative	72205083	C28H33BrN4O6S	633.6	CC1=C([N+](=C(N1C2=CC=CC=C2)SCC(=O)CC[C@@H](C(=O)O)NC(=O)CNC(=O)OCC3=CC=CC=C3)C)C.[Br-]	IC50 > 200000 nM	Non binder
T05387	Tissue transglutaminase	D0SP2O	1H-Indole-2,3-dione	Investigative	7054	C8H5NO2	147.13	C1=CC=C2C(=C1)C(=O)C(=O)N2	IC50 > 250000 nM	Non binder