TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T06093	Rho-associated protein kinase 2	B0YB5I	3-[2-(3,4-Dimethoxy-phenyl)-acetylamino]-N-(2-piperidin-3-ylethyl)-benzamide	Investigative	44819196	C24H31N3O4	425.5	COC1=C(C=C(C=C1)CC(=O)NC2=CC=CC(=C2)C(=O)NCCC3CCCNC3)OC	IC50 = 3200000 nM	Non binder
T06093	Rho-associated protein kinase 2	B10IGT	N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzyl]-3-methoxy-benzamide	Investigative	25054828	C25H27N3O3	417.5	CN(C)CC1=CC=C(C=C1)NC(=O)C2=CC=CC(=C2)CNC(=O)C3=CC(=CC=C3)OC	IC50 > 7000000 nM	Non binder
T06093	Rho-associated protein kinase 2	B1MCV4	4-Cyano-N-[3-(4-dimethylaminomethyl-phenylcarbamoyl)-benzyl]-benzamide	Investigative	25054571	C25H24N4O2	412.5	CN(C)CC1=CC=C(C=C1)NC(=O)C2=CC=CC(=C2)CNC(=O)C3=CC=C(C=C3)C#N	IC50 = 1700000 nM	Non binder
T06093	Rho-associated protein kinase 2	B2MW4R	4-Methoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)-benzyl]-benzamide	Investigative	44819016	C23H23N3O3	389.4	COC1=CC=C(C=C1)C(=O)NCC2=CC(=CC=C2)C(=O)NCCC3=CC=NC=C3	IC50 > 7000000 nM	Non binder
T06093	Rho-associated protein kinase 2	B60PIE	3-[(3,4-Dimethoxyphenyl)carbamoylamino]-N-(2-piperidin-3-ylethyl)benzamide	Investigative	44819194	C23H30N4O4	426.5	COC1=C(C=C(C=C1)NC(=O)NC2=CC=CC(=C2)C(=O)NCCC3CCCNC3)OC	IC50 > 7000000 nM	Non binder
T06093	Rho-associated protein kinase 2	B7RLU8	N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzyl]-4-methoxy-3-methyl-benzamide	Investigative	25054568	C26H29N3O3	431.5	CC1=C(C=CC(=C1)C(=O)NCC2=CC(=CC=C2)C(=O)NC3=CC=C(C=C3)CN(C)C)OC	IC50 = 266000 nM	Non binder
T06093	Rho-associated protein kinase 2	B8DN5G	5-(4-Fluorophenyl)-N-pyridin-4-ylpyridine-3-carboxamide	Investigative	70687744	C17H12FN3O	293.29	C1=CC(=CC=C1C2=CC(=CN=C2)C(=O)NC3=CC=NC=C3)F	IC50 > 400000 nM	Non binder
T06093	Rho-associated protein kinase 2	BALS74	3-[3-(3-Amido-phenyl)-ureidomethyl]-N-(4-dimethylaminomethylphenyl)-benzamide	Investigative	44819374	C25H27N5O3	445.5	CN(C)CC1=CC=C(C=C1)NC(=O)C2=CC=CC(=C2)CNC(=O)NC3=CC=CC(=C3)C(=O)N	IC50 = 240000 nM	Non binder
T06093	Rho-associated protein kinase 2	BAM3U2	4-(4-Fluorophenyl)-N-pyridin-4-ylpyridine-3-carboxamide	Investigative	70691933	C17H12FN3O	293.29	C1=CC(=CC=C1C2=C(C=NC=C2)C(=O)NC3=CC=NC=C3)F	IC50 > 400000 nM	Non binder
T06093	Rho-associated protein kinase 2	BB4W8T	5-Bromo-N-(pyridin-4-yl)pyridine-3-carboxamide	Investigative	2227730	C11H8BrN3O	278.1	C1=CN=CC=C1NC(=O)C2=CC(=CN=C2)Br	IC50 = 357200 nM	Non binder
T06093	Rho-associated protein kinase 2	BBH6L0	3-[3-(3,4-Dimethoxy-phenyl)-ureidomethyl]-N-(2-piperidin-3-ylethyl)-benzamide	Investigative	25056630	C24H32N4O4	440.5	COC1=C(C=C(C=C1)NC(=O)NCC2=CC(=CC=C2)C(=O)NCCC3CCCNC3)OC	IC50 = 1600000 nM	Non binder
T06093	Rho-associated protein kinase 2	BBX7O9	3-[(3,4-Dimethoxy-benzenesulfonylamino)-methyl]-N-(2-piperidin-3-yl-ethyl)-benzamide	Investigative	44819369	C23H31N3O5S	461.6	COC1=C(C=C(C=C1)S(=O)(=O)NCC2=CC(=CC=C2)C(=O)NCCC3CCCNC3)OC	IC50 > 6000000 nM	Non binder
T06093	Rho-associated protein kinase 2	BDR7O9	4-Chloro-N-pyridin-4-ylpyridine-3-carboxamide	Investigative	70691888	C11H8ClN3O	233.65	C1=CN=CC=C1NC(=O)C2=C(C=CN=C2)Cl	IC50 = 221400 nM	Non binder
T06093	Rho-associated protein kinase 2	BE3GC8	3-Methoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)-benzyl]-benzamide	Investigative	44819017	C23H23N3O3	389.4	COC1=CC=CC(=C1)C(=O)NCC2=CC(=CC=C2)C(=O)NCCC3=CC=NC=C3	IC50 > 7000000 nM	Non binder
T06093	Rho-associated protein kinase 2	BFP54A	N-(3,4-Dimethoxy-benzyl)-N-(2-piperidin-3-yl-ethyl)-isophthalamide	Investigative	44819195	C24H31N3O4	425.5	COC1=C(C=C(C=C1)CNC(=O)C2=CC=CC(=C2)C(=O)NCCC3CCCNC3)OC	IC50 > 6000000 nM	Non binder
T06093	Rho-associated protein kinase 2	BGF5N6	3,4-Dimethyl-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)-benzyl]-benzamide	Investigative	44819019	C24H25N3O2	387.5	CC1=C(C=C(C=C1)C(=O)NCC2=CC(=CC=C2)C(=O)NCCC3=CC=NC=C3)C	IC50 > 7000000 nM	Non binder
T06093	Rho-associated protein kinase 2	BLAS25	N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzyl]-3,4-dihydroxy-benzamide	Investigative	44819370	C24H25N3O4	419.5	CN(C)CC1=CC=C(C=C1)NC(=O)C2=CC=CC(=C2)CNC(=O)C3=CC(=C(C=C3)O)O	IC50 > 6000000 nM	Non binder
T06093	Rho-associated protein kinase 2	BQ1YP6	N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzyl]-4-methoxy-benzamide	Investigative	25054569	C25H27N3O3	417.5	CN(C)CC1=CC=C(C=C1)NC(=O)C2=CC=CC(=C2)CNC(=O)C3=CC=C(C=C3)OC	IC50 = 1300000 nM	Non binder
T06093	Rho-associated protein kinase 2	BR3I5X	3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamoyl)-benzyl]-4-trifluoromethoxy-benzamide	Investigative	25055076	C25H23ClF3N3O3	505.9	CN(C)CC1=CC=C(C=C1)NC(=O)C2=CC=CC(=C2)CNC(=O)C3=CC(=C(C=C3)OC(F)(F)F)Cl	IC50 = 670000 nM	Non binder
T06093	Rho-associated protein kinase 2	BRTJ61	3,4-Dimethoxy-N-[3-(2-piperidin-3-yl-ethylcarbamoyl)-phenyl]-benzamide	Investigative	44819197	C23H29N3O4	411.5	COC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(=O)NCCC3CCCNC3)OC	IC50 > 6000000 nM	Non binder
T06093	Rho-associated protein kinase 2	BU6TS1	1,3-Benzodioxole-5-carboxylic acid 3-(2-pyridin-4-yl-ethylcarbamoyl)-benzylamide	Investigative	44819018	C23H21N3O4	403.4	C1OC2=C(O1)C=C(C=C2)C(=O)NCC3=CC(=CC=C3)C(=O)NCCC4=CC=NC=C4	IC50 > 7000000 nM	Non binder
T06093	Rho-associated protein kinase 2	BX35ED	N-[3-(Isoquinolin-6-ylcarbamoyl)-benzyl]-3,4-dimethoxy-benzamide	Investigative	44819192	C26H23N3O4	441.5	COC1=C(C=C(C=C1)C(=O)NCC2=CC(=CC=C2)C(=O)NC3=CC4=C(C=C3)C=NC=C4)OC	IC50 = 685000 nM	Non binder