TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T07173	Tropomyosin-related kinase A	B2Q7ZJ	4-Methyl-N-[5-(7-propan-2-ylpyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-3-yl]pyridine-3-carboxamide	Investigative	90683957	C22H20N6O2	400.4	CC1=C(C=NC=C1)C(=O)NC2=CN=CC(=C2)C(=O)C3=CN(C4=NC=NC=C34)C(C)C	IC50 = 9800000000 nM	Non binder
T07173	Tropomyosin-related kinase A	B86UHF	10-Methoxy-5-methylindeno[2,3-b]quinoline-6,11-dione	Investigative	122194432	C18H13NO3	291.3	CN1C2=CC=CC=C2C(=O)C3=C1C(=O)C4=C3C(=CC=C4)OC	IC50 = 209000 nM	Non binder
T07173	Tropomyosin-related kinase A	BNBD35	Chembl4217454	Investigative	118665613	C25H28F4N2O6	528.5	CC(C)(COC1=CC(=C(C=C1)C(=O)N)O[C@@H]2CCN(C[C@H]2F)C(=O)CC3=CC=C(C=C3)OC(F)(F)F)O	IC50 = 410000 nM	Non binder
T07173	Tropomyosin-related kinase A	BSEB16	2-[[1-Cyclopentyl-5-[1-(Oxetan-3-Yl)piperidin-4-Yl]pyrazol-3-Yl]amino]pyridine-4-Carbonitrile	Investigative	91936970	C22H28N6O	392.5	C1CCC(C1)N2C(=CC(=N2)NC3=NC=CC(=C3)C#N)C4CCN(CC4)C5COC5	IC50 = 464000 nM	Non binder