TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T08391	Janus kinase 2	D06CIJ	ISIS-CRP	Phase 1	4878	C15H16ClN5	301.77	CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)Cl)N	IC50 > 50000000 nM	Non binder
T08391	Janus kinase 2	BDRQ89	N-(6-(6,7-Dimethoxyquinolin-4-yloxy)-1-methyl-1H-indazol-3-yl)-3-(trifluoromethyl)benzamide	Investigative	11398307	C27H21F3N4O4	522.5	CN1C2=C(C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)C(=N1)NC(=O)C5=CC(=CC=C5)C(F)(F)F	IC50 = 25000000 nM	Non binder
T08391	Janus kinase 2	BH2GI7	1-(2-Aminoethyl)-2-(4-piperidinyl)-1H-benzoimidazole-5-carboxamide	Investigative	122192069	C15H21N5O	287.36	C1CNCCC1C2=NC3=C(N2CCN)C=CC(=C3)C(=O)N	IC50 = 437300 nM	Non binder