TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T08856	Matrix metalloproteinase-8	B3K4BP	Chembl4171886	Investigative	145950074	C12H15N3O7S	345.33	CNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 = 401100 nM	Non binder
T08856	Matrix metalloproteinase-8	B5WC9O	1-(4-Phenoxyphenethyl)-3-hydroxy-1-methylurea	Investigative	44405998	C16H18N2O3	286.33	CN(CCC1=CC=C(C=C1)OC2=CC=CC=C2)C(=O)NO	IC50 = 1000000 nM	Non binder
T08856	Matrix metalloproteinase-8	B6P5EB	[(2S)-3-[[(2S)-1-Amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-oxo-2-[2-(trifluoromethoxy)phenyl]sulfanylpropyl]-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphinic acid	Investigative	71451330	C37H36F3N4O7PS	768.7	C1=CC=C(C=C1)C[C@H](NC(=O)OCC2=CC=CC=C2)P(=O)(C[C@H](C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N)SC5=CC=CC=C5OC(F)(F)F)O	Ki > 200000 nM	Non binder
T08856	Matrix metalloproteinase-8	B8R9AG	D-Leucyl-L-phenylalanine methylamide	Investigative	15296844	C16H25N3O2	291.39	CC(C)C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC)N	IC50 > 300000 nM	Non binder
T08856	Matrix metalloproteinase-8	B93MOD	1-(4-Phenoxyphenethyl)-3-hydroxyurea	Investigative	44405997	C15H16N2O3	272.3	C1=CC=C(C=C1)OC2=CC=C(C=C2)CCNC(=O)NO	IC50 > 380000 nM	Non binder
T08856	Matrix metalloproteinase-8	BEU14G	Chembl4175156	Investigative	145949783	C16H23N3O7S	401.4	CCCCCNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 > 500000 nM	Non binder
T08856	Matrix metalloproteinase-8	BFZ5I0	Chembl4167291	Investigative	145955226	C15H21N3O7S	387.4	CC(C)CNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 = 483100 nM	Non binder
T08856	Matrix metalloproteinase-8	BL58TM	Chembl4162521	Investigative	145957734	C15H21N3O7S	387.4	CCCCNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 = 345800 nM	Non binder
T08856	Matrix metalloproteinase-8	BSK63Q	Z-L-Leu-L-Phe-OMe	Investigative	13968141	C24H30N2O5	426.5	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)OC)NC(=O)OCC2=CC=CC=C2	IC50 > 300000 nM	Non binder
T08856	Matrix metalloproteinase-8	BX28NQ	Chembl4164016	Investigative	145960035	C13H17N3O7S	359.36	CCNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 = 298500 nM	Non binder
T08856	Matrix metalloproteinase-8	BXH05U	Chembl4170455	Investigative	145956298	C14H19N3O7S	373.38	CC(C)NC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 > 500000 nM	Non binder
T08856	Matrix metalloproteinase-8	BZSF06	N-{2-[(4'-Cyano-1,1'-biphenyl-4-YL)oxy]ethyl}-N'-hydroxy-N-methylurea	Investigative	5326979	C17H17N3O3	311.33	CN(CCOC1=CC=C(C=C1)C2=CC=C(C=C2)C#N)C(=O)NO	IC50 = 1200000 nM	Non binder