TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T11388	Cathepsin K	B2UH7L	Tert-butyl N-{[(cyanomethyl)carbamoyl]methyl}carbamate	Investigative	14060550	C9H15N3O3	213.23	CC(C)(C)OC(=O)NCC(=O)NCC#N	Ki > 1000000 nM	Non binder
T11388	Cathepsin K	B6AS7O	Benzyl N-[(2S)-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate	Investigative	73351955	C29H41N5O5	539.7	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)OCC2=CC=CC=C2	Ki = 213000 nM	Non binder
T11388	Cathepsin K	B6Y8LN	(S)-Tert-Butyl (1-oxo-3-phenyl-1-(prop-2-yn-1-ylamino)propan-2-yl)carbamate	Investigative	11673861	C17H22N2O3	302.37	CC(C)(C)OC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC#C	Ki > 1000000 nM	Non binder
T11388	Cathepsin K	B97LNW	Benzyl N-[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxohexan-2-yl]carbamate	Investigative	73348858	C29H42N6O5	554.7	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@H](CCCCN)NC(=O)OCC2=CC=CC=C2	Ki = 284000 nM	Non binder
T11388	Cathepsin K	BB24YL	Phenylalanine derived allylamide, 55	Investigative	14308232	C17H24N2O3	304.4	CC(C)(C)OC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC=C	Ki > 1000000 nM	Non binder
T11388	Cathepsin K	BE65FP	Benzyl N-[(2S)-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamate	Investigative	73345852	C34H40N6O5	612.7	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)OCC4=CC=CC=C4	Ki = 639000 nM	Non binder
T11388	Cathepsin K	BN6B4J	[(S)-1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (S)-2,2-dimethyl-1-(5-phenyl-[1,3,4]oxadiazol-2-ylmethyl)-propyl ester	Investigative	10230391	C30H38N4O5	534.6	CCCC[C@@H](C(=O)C(=O)N[C@H](C)C1=CC=CC=C1)NC(=O)O[C@@H](CC2=NN=C(O2)C3=CC=CC=C3)C(C)(C)C	IC50 = 460000 nM	Non binder
T11388	Cathepsin K	BU58ET	Dipeptide-derived nitrile, 2	Investigative	15567852	C12H13N3O3	247.25	C1=CC=C(C=C1)COC(=O)NCC(=O)NCC#N	Ki > 1000000 nM	Non binder