TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T13260	Aromatase	B0IS4W	Lafis-10	Investigative	25111796	C42H72N4O3	681	C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OC(=O)C)C)C)[C@@H]2[C@H]1C)C)C(=O)NCCCN6CCN(CC6)CCCN	IC50 > 500000 nM	Non binder
T13260	Aromatase	B0VN1X	4-[(Z)-(6-Methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)methyl]pyridine	Investigative	6539799	C17H17NO	251.32	COC1=CC2=C(C=C1)/C(=C\\C3=CC=NC=C3)/CCC2	IC50 = 1009252.89 nM	Non binder
T13260	Aromatase	B0YZN1	2-(Hydroxy-pyrazin-2-yl-methyl)-3,4-dihydro-2H-naphthalen-1-one	Investigative	10753431	C15H14N2O2	254.28	C1CC2=CC=CC=C2C(=O)C1C(C3=NC=CN=C3)O	IC50 > 250000 nM	Non binder
T13260	Aromatase	B1A5XQ	1-[2-Hydroxy-4-(methoxymethoxy)phenyl]-3-[4-methoxy-3-(3-methylbut-2-enyl)phenyl]prop-2-en-1-one	Investigative	16737077	C23H26O5	382.4	CC(=CCC1=C(C=CC(=C1)/C=C/C(=O)C2=C(C=C(C=C2)OCOC)O)OC)C	IC50 > 261500 nM	Non binder
T13260	Aromatase	B1E6NY	3-Phenyl-7-phenylmethoxy-2-(pyridin-4-ylmethylsulfanyl)chromen-4-one	Investigative	10026826	C28H21NO3S	451.5	C1=CC=C(C=C1)COC2=CC3=C(C=C2)C(=O)C(=C(O3)SCC4=CC=NC=C4)C5=CC=CC=C5	IC50 = 210000 nM	Non binder
T13260	Aromatase	B1WY8D	3-[(Z)-(6-Methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)methyl]pyridine	Investigative	6539772	C17H17NO	251.32	COC1=CC2=C(C=C1)/C(=C\\C3=CN=CC=C3)/CCC2	IC50 = 3999447.5 nM	Non binder
T13260	Aromatase	B2PIR9	3,4-Dihydro-2-[(E)-(3-thienyl)methylene]naphthalen-1(2H)-one	Investigative	7515053	C15H12OS	240.3	C1C/C(=C\\C2=CSC=C2)/C(=O)C3=CC=CC=C31	IC50 > 250000 nM	Non binder
T13260	Aromatase	B3R6AS	2-(Hydroxy-pyridazin-4-yl-methyl)-3,4-dihydro-2H-naphthalen-1-one	Investigative	10729611	C15H14N2O2	254.28	C1CC2=CC=CC=C2C(=O)C1C(C3=CN=NC=C3)O	IC50 > 250000 nM	Non binder
T13260	Aromatase	B3TXZ4	1-Phenyl-1a,2,3,7b-tetrahydro-1H-cyclopropa[a]naphthalene	Investigative	44381001	C17H16	220.31	C1CC2=CC=CC=C2C3C1C3C4=CC=CC=C4	IC50 > 250000 nM	Non binder
T13260	Aromatase	B57IOY	2-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen-1-yl)-pyridine	Investigative	10656613	C16H15N	221.3	C1CC2=CC=CC=C2C3C1C3C4=CC=CC=N4	IC50 > 250000 nM	Non binder
T13260	Aromatase	B5WHC2	Ursonic acid	Investigative	9890209	C30H46O3	454.7	C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CCC(=O)C5(C)C)C)C)[C@@H]2[C@H]1C)C)C(=O)O	IC50 > 500000 nM	Non binder
T13260	Aromatase	B65MHD	3,4-Dihydro-2-[(E)-(pyridazin-3-yl)methylene]naphthalen-1(2H)-one	Investigative	10776192	C15H12N2O	236.27	C1C/C(=C\\C2=NN=CC=C2)/C(=O)C3=CC=CC=C31	IC50 > 250000 nM	Non binder
T13260	Aromatase	B6L0CS	1-(2-Hydroxy-4-methoxyphenyl)-3-[4-(3-methylbut-2-enyloxy)phenyl]prop-2-en-1-one	Investigative	16737167	C21H22O4	338.4	CC(=CCOC1=CC=C(C=C1)/C=C/C(=O)C2=C(C=C(C=C2)OC)O)C	IC50 > 271400 nM	Non binder
T13260	Aromatase	B6YR2N	2-(2-Pyridylmethylene)-3,4-dihydro-1(2H)-naphthalenone	Investigative	5702960	C16H13NO	235.28	C1C/C(=C\\C2=CC=CC=N2)/C(=O)C3=CC=CC=C31	IC50 > 250000 nM	Non binder
T13260	Aromatase	B7GD9W	(3-Pyridylmethylene)tetrahydronaphthalene 17a	Investigative	6539778	C18H19NO2	281.3	COC1=C(C=C\\2C(=C1)CCC/C2=C\\C3=CN=CC=C3)OC	IC50 = 979489.99 nM	Non binder
T13260	Aromatase	B7WMT3	4-{[(1E)-6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-ylidene]methyl}pyridine	Investigative	6539798	C17H17NO	251.32	COC1=CC2=C(C=C1)/C(=C/C3=CC=NC=C3)/CCC2	IC50 = 799834.26 nM	Non binder
T13260	Aromatase	B81EDN	1-(2-Hydroxy-4-methoxyphenyl)-3-[3-(3-methylbut-2-enyl)-phenyl]prop-2-en-1-one	Investigative	16738422	C21H22O3	322.4	CC(=CCC1=CC(=CC=C1)/C=C/C(=O)C2=C(C=C(C=C2)OC)O)C	IC50 > 310200 nM	Non binder
T13260	Aromatase	B8XA9B	4'-Hydroxytamoxifen	Investigative	5284643	C26H29NO2	387.5	CC/C(=C(\\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=C(C=C3)O	IC50 = 530000 nM	Non binder
T13260	Aromatase	B94TVB	(1S,5R)-1-(4-Aminophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione	Investigative	44276238	C11H10N2O2	202.21	C1[C@@H]2[C@]1(C(=O)NC2=O)C3=CC=C(C=C3)N	IC50 = 777000 nM	Non binder
T13260	Aromatase	B9A7EO	(Isoquinolinemethylene)indane 30a	Investigative	6539812	C19H14FN	275.3	C1C/C(=C\\C2=CC=CC3=C2C=CN=C3)/C4=C1C=C(C=C4)F	IC50 = 719448.98 nM	Non binder
T13260	Aromatase	B9NG5O	1,3-Diethyl-3-pyridin-4-ylpiperidine-2,6-dione	Investigative	13900578	C14H18N2O2	246.3	CCC1(CCC(=O)N(C1=O)CC)C2=CC=NC=C2	IC50 = 385000 nM	Non binder
T13260	Aromatase	BACF50	3-{[(1E)-6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-ylidene]methyl}pyridine	Investigative	6539771	C17H17NO	251.32	COC1=CC2=C(C=C1)/C(=C/C3=CN=CC=C3)/CCC2	IC50 = 1129795.91 nM	Non binder
T13260	Aromatase	BAG9J5	N-{3-[4-(3-Aminopropyl)piperazinyl]propyl}-ursolamide	Investigative	25111799	C40H70N4O2	639	C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)C(=O)NCCCN6CCN(CC6)CCCN	IC50 > 500000 nM	Non binder
T13260	Aromatase	BAW59K	7-(Benzyloxy)-2-(1H-imidazol-1-yl)-3-(4-methoxyphenyl)-4H-chromen-4-one	Investigative	23644934	C26H20N2O4	424.4	COC1=CC=C(C=C1)C2=C(OC3=C(C2=O)C=CC(=C3)OCC4=CC=CC=C4)N5C=CN=C5	IC50 = 4680000000000 nM	Non binder
T13260	Aromatase	BB1DT2	Afimoxifene	Investigative	63062	C26H29NO2	387.5	CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3	IC50 = 530000 nM	Non binder
T13260	Aromatase	BD35EN	7-(Benzyloxy)-2-(1H-imidazol-1-yl)-3-phenyl-4H-chromen-4-one	Investigative	23644933	C25H18N2O3	394.4	C1=CC=C(C=C1)COC2=CC3=C(C=C2)C(=O)C(=C(O3)N4C=CN=C4)C5=CC=CC=C5	IC50 = 513000000000 nM	Non binder
T13260	Aromatase	BE65KU	5-{[(1Z)-5-Fluoro-2,3-dihydro-1H-inden-1-ylidene]methyl}isoquinoline	Investigative	6539813	C19H14FN	275.3	C1C/C(=C/C2=CC=CC3=C2C=CN=C3)/C4=C1C=C(C=C4)F	IC50 = 1940885.88 nM	Non binder
T13260	Aromatase	BF1YM6	3-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen-1-yl)-thiophene	Investigative	10585362	C15H14S	226.3	C1CC2=CC=CC=C2C3C1C3C4=CSC=C4	IC50 > 250000 nM	Non binder
T13260	Aromatase	BFV39G	4-[(E)-3,4-Dihydro-2H-naphthalen-1-ylidenemethyl]pyridine	Investigative	6539787	C16H15N	221.3	C1CC2=CC=CC=C2/C(=C/C3=CC=NC=C3)/C1	IC50 = 650129.69 nM	Non binder
T13260	Aromatase	BH4PN2	1-[2-Hydroxy-4-(methoxymethoxy)phenyl]-3-[3-(3-methyl-2-butenyl)-4-(methoxymethoxy)phenyl]-2-propene-1-one	Investigative	15516845	C24H28O6	412.5	CC(=CCC1=C(C=CC(=C1)/C=C/C(=O)C2=C(C=C(C=C2)OCOC)O)OCOC)C	IC50 > 242400 nM	Non binder
T13260	Aromatase	BH63AY	3',4'-Dihydroxyisoflavanone	Investigative	57679076	C15H12O4	256.25	C1C(C(=O)C2=CC=CC=C2O1)C3=CC(=C(C=C3)O)O	IC50 >= 200000 nM	Non binder
T13260	Aromatase	BHD62Q	(S)-Aminoglutethimide	Investigative	1548995	C13H16N2O2	232.28	CC[C@]1(CCC(=O)NC1=O)C2=CC=C(C=C2)N	IC50 = 370000 nM	Non binder
T13260	Aromatase	BHM1U9	2,6-Piperidinedione, 3-methyl-3-(4-pyridinyl)-	Investigative	13537950	C11H12N2O2	204.22	CC1(CCC(=O)NC1=O)C2=CC=NC=C2	IC50 = 245000 nM	Non binder
T13260	Aromatase	BI4KO7	4-Aza-A-homo-3-oxo-ursolic acid	Investigative	44562549	C30H47NO3	469.7	C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CCC(=O)NC5(C)C)C)C)[C@@H]2[C@H]1C)C)C(=O)O	IC50 > 500000 nM	Non binder
T13260	Aromatase	BI9V4C	3-[(Z)-3,4-Dihydro-2H-naphthalen-1-ylidenemethyl]pyridine	Investigative	6539762	C16H15N	221.3	C1CC2=CC=CC=C2/C(=C\\C3=CN=CC=C3)/C1	IC50 = 3793149.85 nM	Non binder
T13260	Aromatase	BIH9G6	3-Methyl-4,5-dihydro-3H-[3,4'']bipyridinyl-2,6-dione	Investigative	44323741	C11H12N2O2	204.22	C[C@@]1(CCC(=O)NC1=O)C2=CC=NC=C2	IC50 = 245000 nM	Non binder
T13260	Aromatase	BK19JI	1-(2-Hydroxy-4-methoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one	Investigative	5357488	C17H16O4	284.31	COC1=CC=C(C=C1)/C=C/C(=O)C2=C(C=C(C=C2)OC)O	IC50 > 351700 nM	Non binder
T13260	Aromatase	BK9FB4	3,4-Dihydro-2-[(E)-(2-aminothiazol-5-yl)methylene]naphthalen-1(2H)-one	Investigative	10587179	C14H12N2OS	256.32	C1C/C(=C\\C2=CN=C(S2)N)/C(=O)C3=CC=CC=C31	IC50 > 250000 nM	Non binder
T13260	Aromatase	BL48CW	9-Methoxy-6,6aalpha,11,11aalpha-tetrahydro[1]benzopyrano[4,3-b]indole-3-ol	Investigative	76329384	C16H15NO3	269.29	COC1=CC2=C(C=C1)[C@@H]3COC4=C([C@@H]3N2)C=CC(=C4)O	IC50 > 300000 nM	Non binder
T13260	Aromatase	BOF1R8	3-(4-Aminophenyl)piperidine-2,6-dione	Investigative	13660214	C11H12N2O2	204.22	C1CC(=O)NC(=O)C1C2=CC=C(C=C2)N	IC50 > 300000 nM	Non binder
T13260	Aromatase	BS9J8H	1-(2-Hydroxy-4-methoxyphenyl)-3-[4-methoxy-3-(3-methylbut-2-enyl)phenyl]prop-2-en-1-one	Investigative	16738409	C22H24O4	352.4	CC(=CCC1=C(C=CC(=C1)/C=C/C(=O)C2=C(C=C(C=C2)OC)O)OC)C	IC50 > 283750 nM	Non binder
T13260	Aromatase	BU6T3L	2,4b-Dimethyl-7-oxo-1,2,3,4,4a,4b,7,9,10,10a-decahydro-phenanthrene-2-carboxylic acid	Investigative	14442762	C17H22O3	274.35	CC1(CCC2C(C1)CCC3=CC(=O)C=CC23C)C(=O)O	Ki = 893000 nM	Non binder
T13260	Aromatase	BU9Y0B	3-[4-Hydroxy-3-(3-methylbut-2-enyl)phenyl]-1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one	Investigative	16738421	C21H22O4	338.4	CC(=CCC1=C(C=CC(=C1)/C=C/C(=O)C2=C(C=C(C=C2)OC)O)O)C	IC50 > 295500 nM	Non binder
T13260	Aromatase	BV51IZ	2-(Hydroxy-pyridazin-3-yl-methyl)-3,4-dihydro-2H-naphthalen-1-one	Investigative	10610950	C15H14N2O2	254.28	C1CC2=CC=CC=C2C(=O)C1C(C3=NN=CC=C3)O	IC50 > 250000 nM	Non binder
T13260	Aromatase	BVXK85	2-Benzylidene-1-tetralone	Investigative	5376779	C17H14O	234.29	C1C/C(=C\\C2=CC=CC=C2)/C(=O)C3=CC=CC=C31	IC50 > 250000 nM	Non binder
T13260	Aromatase	BWO4G9	7-Methoxy-3-phenyl-2-(1H-1,2,4-triazol-1-yl)-4H-chromen-4-one	Investigative	23644935	C18H13N3O3	319.3	COC1=CC2=C(C=C1)C(=O)C(=C(O2)N3C=NC=N3)C4=CC=CC=C4	IC50 = 18200000000000 nM	Non binder
T13260	Aromatase	BX97CQ	1-(2-Hydroxy-4-methoxyphenyl)-3-[4-(methoxymethoxy)-3-(3-methylbut-2-enyl)phenyl]prop-2-en-1-one	Investigative	16737078	C23H26O5	382.4	CC(=CCC1=C(C=CC(=C1)/C=C/C(=O)C2=C(C=C(C=C2)OC)O)OCOC)C	IC50 > 261500 nM	Non binder
T13260	Aromatase	BY6K3U	1-(2-Hydroxyphenyl)-3-[4-methoxy-3-(3-methylbut-2-enyl)-phenyl]prop-2-en-1-one	Investigative	44424773	C21H24O3	324.4	CC(=CCC1=C(C=CC(=C1)/C=C/C(C2=CC=CC=C2O)O)OC)C	IC50 > 310170 nM	Non binder
T13260	Aromatase	BY7GA8	2-Cyano-2,3-seco-4-yliden-olean-12-enoic acid	Investigative	44562528	C30H45NO2	451.7	C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@H]([C@]4(C)CCC#N)C(=C)C)C)[C@@H]2[C@H]1C)C)C(=O)O	IC50 > 500000 nM	Non binder
T13260	Aromatase	BYU7M3	2-(1H-Imidazol-1-yl)-7-methoxy-3-(4-methoxyphenyl)-4H-chromen-4-one	Investigative	23644932	C20H16N2O4	348.4	COC1=CC=C(C=C1)C2=C(OC3=C(C2=O)C=CC(=C3)OC)N4C=CN=C4	IC50 = 1950000000000 nM	Non binder
T13260	Aromatase	BZ1Y9S	(3R)-3alpha-Ethyl-5,5-dimethyl-3-(4-pyridinyl)piperidine-2,6-dione	Investigative	15680920	C14H18N2O2	246.3	CC[C@@]1(CC(C(=O)NC1=O)(C)C)C2=CC=NC=C2	IC50 > 200000 nM	Non binder
T13260	Aromatase	BZ8V9C	3-[(1E)-1,2,3,4-Tetrahydronaphthalen-1-ylidenemethyl]pyridine	Investigative	6539761	C16H15N	221.3	C1CC2=CC=CC=C2/C(=C/C3=CN=CC=C3)/C1	IC50 = 6576578.37 nM	Non binder
T13260	Aromatase	BZB25T	(3R)-1,3-Diethyl-3-pyridin-4-ylpiperidine-2,6-dione	Investigative	44323808	C14H18N2O2	246.3	CC[C@@]1(CCC(=O)N(C1=O)CC)C2=CC=NC=C2	IC50 = 385000 nM	Non binder
T13260	Aromatase	BZS8O5	1,2,4b-Trimethyl-7-oxo-1,2,3,4,4a,4b,7,9,10,10a-decahydro-phenanthrene-2-carboxylic acid	Investigative	14442758	C18H24O3	288.4	CC1C2CCC3=CC(=O)C=CC3(C2CCC1(C)C(=O)O)C	Ki = 1198000 nM	Non binder
T13260	Aromatase	D09TUB	LICOAGROCHALCONE A	Investigative	11099375	C20H20O4	324.4	CC(=CCC1=C(C=CC(=C1)/C=C/C(=O)C2=C(C=C(C=C2)O)O)O)C	IC50 > 308300 nM	Non binder
T13260	Aromatase	D09VPA	4-[5-Bromo-indan-(1E)-ylidenemethyl]-pyridine	Investigative	6539794	C15H12BrN	286.17	C1C/C(=C\\C2=CC=NC=C2)/C3=C1C=C(C=C3)Br	IC50 = 3396252.73 nM	Non binder