TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T13348	AP endonuclease 1	B0YQJ3	3-(4-Bromothiophen-2-yl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione	Investigative	16481078	C11H8BrN5O2S	354.18	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3=CC(=CS3)Br)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B23YQC	1-Ethyl-3-(4-ethylphenyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione	Investigative	4989139	C16H17N5O2	311.34	CCC1=CC=C(C=C1)C2=NN(C3=NC(=O)N(C(=O)C3=N2)C)CC	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B2D1ZC	3-[4-(3,4-Dimethoxyphenyl)thiophen-2-yl]-N-methylsulfonylbenzamide	Investigative	71818443	C20H19NO5S2	417.5	COC1=C(C=C(C=C1)C2=CSC(=C2)C3=CC(=CC=C3)C(=O)NS(=O)(=O)C)OC	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B2KE1H	N-[4-(3,4-Dimethoxyphenyl)thiophen-2-yl]-1-methyl-6-oxo-5-phenylmethoxypyrimidine-4-carboxamide	Investigative	71818293	C25H23N3O5S	477.5	CN1C=NC(=C(C1=O)OCC2=CC=CC=C2)C(=O)NC3=CC(=CS3)C4=CC(=C(C=C4)OC)OC	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B2ST7P	N-[3-(2,4-Dioxopyrimido[4,5-b]quinolin-10-yl)phenyl]methanesulfonamide	Investigative	71819144	C18H14N4O4S	382.4	CS(=O)(=O)NC1=CC(=CC=C1)N2C3=CC=CC=C3C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B2WJ0C	3-[4-(3,4-Dimethoxyphenyl)thiophen-2-yl]-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71818146	C19H17N5O4S	411.4	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3=CC(=CS3)C4=CC(=C(C=C4)OC)OC)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B30MHS	1-(Cyclopropylmethyl)-3-(4-ethylphenyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	73350770	C18H19N5O2	337.4	CCC1=CC=C(C=C1)C2=NN(C3=NC(=O)N(C(=O)C3=N2)C)CC4CC4	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B32FWK	Schembl21221794	Investigative	71818868	C18H10N4O3	330.3	C1=CC(=CC(=C1)O)N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B3YL2K	10-(3-Hydroxy-4-methoxyphenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile	Investigative	71819006	C19H12N4O4	360.3	COC1=C(C=C(C=C1)N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O)O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B40GAR	6-Chloro-4-hydroxy-10-phenylpyrimido[4,5-b]quinolin-2(10H)-one	Investigative	931081	C17H10ClN3O2	323.7	C1=CC=C(C=C1)N2C3=C(C=C4C2=NC(=O)NC4=O)C(=CC=C3)Cl	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B4C3SD	1,6-Dimethyl-3-(m-tolyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione	Investigative	71817698	C14H13N5O2	283.29	CC1=CC(=CC=C1)C2=NN(C3=NC(=O)N(C(=O)C3=N2)C)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B4YC7H	6-(4-Ethylphenyl)-1,3-dimethylpteridine-2,4-dione	Investigative	71818149	C16H16N4O2	296.32	CCC1=CC=C(C=C1)C2=CN=C3C(=N2)C(=O)N(C(=O)N3C)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B58AUY	3-(4-Ethylphenyl)-1-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71818002	C14H13N5O2	283.29	CCC1=CC=C(C=C1)C2=NN(C3=NC(=O)NC(=O)C3=N2)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B59TAO	N-[3-(7-Chloro-2,4-dioxopyrimido[4,5-b]quinolin-10-yl)phenyl]methanesulfonamide	Investigative	71819145	C18H13ClN4O4S	416.8	CS(=O)(=O)NC1=CC(=CC=C1)N2C3=C(C=C(C=C3)Cl)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B5PH2K	1,6-Dimethyl-3-(4-methylphenyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	6459022	C14H13N5O2	283.29	CC1=CC=C(C=C1)C2=NN(C3=NC(=O)N(C(=O)C3=N2)C)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B5W4JO	1,6-Dimethyl-3-(4-methylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71818144	C12H11N5O2S	289.32	CC1=CSC(=C1)C2=NN(C3=NC(=O)N(C(=O)C3=N2)C)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B60WFM	1,6-Dimethyl-3-(1,3-thiazol-4-yl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71818143	C10H8N6O2S	276.28	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3=CSC=N3)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B70HSI	10-Phenyl-8-(trifluoromethyl)pyrimido[4,5-b]quinoline-2,4-dione	Investigative	71818866	C18H10F3N3O2	357.3	C1=CC=C(C=C1)N2C3=C(C=CC(=C3)C(F)(F)F)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B7R5AF	8-Chloro-3-methyl-10-phenylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione	Investigative	866938	C18H12ClN3O2	337.8	CN1C(=O)C2=CC3=C(C=C(C=C3)Cl)N(C2=NC1=O)C4=CC=CC=C4	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B7TA3O	3-Benzyl-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	6458554	C14H13N5O2	283.29	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)CC3=CC=CC=C3)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B7TP2C	8-Chloro-10-piperidin-4-ylpyrimido[4,5-b]quinoline-2,4-dione	Investigative	71818721	C16H15ClN4O2	330.77	C1CNCCC1N2C3=C(C=CC(=C3)Cl)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B7WTM9	[1-[4-(3,4-Dimethoxyphenyl)thiophene-2-carbonyl]piperidin-3-yl]-dimethoxyphosphorylmethanone	Investigative	71818296	C21H26NO7PS	467.5	COC1=C(C=C(C=C1)C2=CSC(=C2)C(=O)N3CCCC(C3)C(=O)P(=O)(OC)OC)OC	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B87RZW	10-(3-Methoxyphenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile	Investigative	71819004	C19H12N4O3	344.3	COC1=CC=CC(=C1)N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B8B0PN	3-Cyclohexyl-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	46834048	C13H17N5O2	275.31	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3CCCCC3)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B8FHY2	3-(8-Cyano-2,4-dioxopyrimido[4,5-b]quinolin-10-yl)benzenesulfonamide	Investigative	71819146	C18H11N5O4S	393.4	C1=CC(=CC(=C1)S(=O)(=O)N)N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B8VI0K	10-Benzyl-8-chloro-2-hydroxypyrimido[4,5-b]quinolin-4(10H)-one	Investigative	941846	C18H12ClN3O2	337.8	C1=CC=C(C=C1)CN2C3=C(C=CC(=C3)Cl)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	B91IAL	Pyrimido(5,4-e)-1,2,4-triazine-5,7(1H,6H)-dione, 3-(3,4-dimethoxyphenyl)-1,6-dimethyl-	Investigative	322478	C15H15N5O4	329.31	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3=CC(=C(C=C3)OC)OC)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BA02JX	3-Cyclopropyl-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	46834317	C10H11N5O2	233.23	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3CC3)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BAY8E1	7-Amino-1-methyl-3-(4-methylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazin-5-one	Investigative	71818291	C11H10N6OS	274.3	CC1=CSC(=C1)C2=NN(C3=NC(=NC(=O)C3=N2)N)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BD0PB1	1,6-Dimethyl-3-(2-phenylethyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	46833159	C15H15N5O2	297.31	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)CCC3=CC=CC=C3)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BE74UK	4-[4-(3,4-Dimethoxyphenyl)thiophen-2-yl]-N-methylsulfonylbenzamide	Investigative	71818444	C20H19NO5S2	417.5	COC1=C(C=C(C=C1)C2=CSC(=C2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C)OC	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BFH9T1	1-Cyclopropyl-3-(4-ethylphenyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71817849	C17H17N5O2	323.35	CCC1=CC=C(C=C1)C2=NN(C3=NC(=O)N(C(=O)C3=N2)C)C4CC4	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BFZ82L	1,6-Dimethyl-3-(oxan-4-yl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71818006	C12H15N5O3	277.28	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3CCOCC3)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BGC6Z4	Pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione,9-chloro-10-phenyl-	Investigative	71818716	C17H10ClN3O2	323.7	C1=CC=C(C=C1)N2C3=C(C=CC=C3Cl)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BI2W4Q	8-Chloro-10-cyclohexylpyrimido[4,5-b]quinoline-2,4-dione	Investigative	71818720	C17H16ClN3O2	329.8	C1CCC(CC1)N2C3=C(C=CC(=C3)Cl)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BK4QC1	Schembl21234361	Investigative	71818867	C18H10N4O2	314.3	C1=CC=C(C=C1)N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BKP6F5	Walrycin B	Investigative	3164070	C14H10F3N5O2	337.26	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3=CC=C(C=C3)C(F)(F)F)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BKS3Q7	10-[3-(Hydroxymethyl)phenyl]-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile	Investigative	71818870	C19H12N4O3	344.3	C1=CC(=CC(=C1)N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O)CO	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BL2SV3	6-Benzyl-3-(4-ethylphenyl)-1-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71818004	C21H19N5O2	373.4	CCC1=CC=C(C=C1)C2=NN(C3=NC(=O)N(C(=O)C3=N2)CC4=CC=CC=C4)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BL54IQ	3-(4-Ethylphenyl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	6493950	C15H15N5O2	297.31	CCC1=CC=C(C=C1)C2=NN(C3=NC(=O)N(C(=O)C3=N2)C)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BL9IN2	8-Chloro-10-(4-methoxyphenyl)pyrimido[4,5-b]quinoline-2,4-dione	Investigative	71818723	C18H12ClN3O3	353.8	COC1=CC=C(C=C1)N2C3=C(C=CC(=C3)Cl)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BLF1K2	1,6-Dimethyl-3-[4-(trifluoromethoxy)phenyl]pyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71817697	C14H10F3N5O3	353.26	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3=CC=C(C=C3)OC(F)(F)F)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BLS25F	8-Chloro-10-(4-hydroxyphenyl)pyrimido[4,5-b]quinoline-2,4-dione	Investigative	71818722	C17H10ClN3O3	339.7	C1=CC(=CC=C1N2C3=C(C=CC(=C3)Cl)C=C4C2=NC(=O)NC4=O)O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BMF8L5	10-(1H-Indazol-6-yl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile	Investigative	71819147	C19H10N6O2	354.3	C1=CC2=C(C=C1C#N)N(C3=NC(=O)NC(=O)C3=C2)C4=CC5=C(C=C4)C=NN5	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BMP3B1	3-(4-Ethylphenyl)-6-methyl-1-propylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71817850	C17H19N5O2	325.4	CCCN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3=CC=C(C=C3)CC)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BNO15S	2,4-Dioxo-10-[3-(1h-Tetrazol-5-Yl)phenyl]-2,3,4,10-Tetrahydropyrimido[4,5-B]quinoline-8-Carbonitrile	Investigative	71819283	C19H10N8O2	382.3	C1=CC(=CC(=C1)N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O)C5=NNN=N5	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BOHC57	10-(1H-Indazol-4-yl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile	Investigative	71819148	C19H10N6O2	354.3	C1=CC2=C(C=NN2)C(=C1)N3C4=C(C=CC(=C4)C#N)C=C5C3=NC(=O)NC5=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BOZ06C	Pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione, 8-chloro-10-phenyl-	Investigative	951230	C17H10ClN3O2	323.7	C1=CC=C(C=C1)N2C3=C(C=CC(=C3)Cl)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BP3GJ5	8-Chloro-10-methylpyrimido[4,5-b]quinoline-2,4-dione	Investigative	71818718	C12H8ClN3O2	261.66	CN1C2=C(C=CC(=C2)Cl)C=C3C1=NC(=O)NC3=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BPH18G	N-[3-(8-Cyano-2,4-dioxopyrimido[4,5-b]quinolin-10-yl)phenyl]methanesulfonamide	Investigative	71819143	C19H13N5O4S	407.4	CS(=O)(=O)NC1=CC(=CC=C1)N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BPN4X5	10-(4-Bromophenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile	Investigative	71819008	C18H9BrN4O2	393.2	C1=CC(=CC=C1N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O)Br	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BPXF42	10-Phenylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione	Investigative	951368	C17H11N3O2	289.29	C1=CC=C(C=C1)N2C3=CC=CC=C3C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BPY58K	1,6-Dimethyl-3-naphthalen-2-ylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71818007	C17H13N5O2	319.32	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3=CC4=CC=CC=C4C=C3)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BQ6E8T	2-[3-(8-Cyano-2,4-dioxopyrimido[4,5-b]quinolin-10-yl)phenyl]acetamide	Investigative	73346151	C20H13N5O3	371.3	C1=CC(=CC(=C1)N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O)CC(=O)N	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BRC13L	10-(3-Fluorophenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile	Investigative	71819007	C18H9FN4O2	332.3	C1=CC(=CC(=C1)F)N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BRQ3B4	7-Chloro-10-phenylpyrimido[4,5-b]quinoline-2,4-dione	Investigative	71818717	C17H10ClN3O2	323.7	C1=CC=C(C=C1)N2C3=C(C=C(C=C3)Cl)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BS0DZ6	10-(3-Aminophenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile	Investigative	71819009	C18H11N5O2	329.3	C1=CC(=CC(=C1)N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O)N	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BTSI49	8-Chloro-10-(3-hydroxyphenyl)pyrimido[4,5-b]quinoline-2,4-dione	Investigative	71818864	C17H10ClN3O3	339.7	C1=CC(=CC(=C1)O)N2C3=C(C=CC(=C3)Cl)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BU3DB9	3-(4-Ethylphenyl)-6-methyl-1-phenylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71817852	C20H17N5O2	359.4	CCC1=CC=C(C=C1)C2=NN(C3=NC(=O)N(C(=O)C3=N2)C)C4=CC=CC=C4	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BU45BO	8-Chloro-10-cyclopropylpyrimido[4,5-b]quinoline-2,4-dione	Investigative	71818719	C14H10ClN3O2	287.7	C1CC1N2C3=C(C=CC(=C3)Cl)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BU59FD	1,6-Dimethyl-3-propylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	3164059	C10H13N5O2	235.24	CCCC1=NN(C2=NC(=O)N(C(=O)C2=N1)C)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BU5IL9	1-Benzyl-3-(4-ethylphenyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71817853	C21H19N5O2	373.4	CCC1=CC=C(C=C1)C2=NN(C3=NC(=O)N(C(=O)C3=N2)C)CC4=CC=CC=C4	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BU7NF0	10-(4-Methoxyphenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile	Investigative	71819005	C19H12N4O3	344.3	COC1=CC=C(C=C1)N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BUN20O	1-Ethyl-3-(4-ethylphenyl)-6-methylpyrimido[4,5-c]pyridazine-5,7-dione	Investigative	71818147	C17H18N4O2	310.35	CCC1=CC=C(C=C1)C2=NN(C3=NC(=O)N(C(=O)C3=C2)C)CC	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BVCT87	8-Chloro-10-(2-hydroxyphenyl)pyrimido[4,5-b]quinoline-2,4-dione	Investigative	71818865	C17H10ClN3O3	339.7	C1=CC=C(C(=C1)N2C3=C(C=CC(=C3)Cl)C=C4C2=NC(=O)NC4=O)O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BWH2O0	1,6-Dimethyl-3-(o-tolyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione	Investigative	3164066	C14H13N5O2	283.29	CC1=CC=CC=C1C2=NN(C3=NC(=O)N(C(=O)C3=N2)C)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BWT2I0	10-(4-Hydroxyphenyl)-2,4-Dioxo-2,3,4,10-Tetrahydropyrimido[4,5-B]quinoline-8-Carbonitrile	Investigative	71818869	C18H10N4O3	330.3	C1=CC(=CC=C1N2C3=C(C=CC(=C3)C#N)C=C4C2=NC(=O)NC4=O)O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BXD5M8	3-(4-Ethylphenyl)-1-methyl-6-phenylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71818003	C20H17N5O2	359.4	CCC1=CC=C(C=C1)C2=NN(C3=NC(=O)N(C(=O)C3=N2)C4=CC=CC=C4)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BXUV02	10-Methylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione	Investigative	267570	C12H9N3O2	227.22	CN1C2=CC=CC=C2C=C3C1=NC(=O)NC3=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BY9RH2	3-(4-Ethylphenyl)-6-methylpyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione	Investigative	6411132	C14H13N5O2	283.29	CCC1=CC=C(C=C1)C2=NC3=C(NC(=O)N(C3=O)C)N=N2	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BYE20C	1,6-Dimethyl-3-phenylpyrimido[5,4-E][1,2,4]triazine-5,7(1H,6H)-dione	Investigative	460748	C13H11N5O2	269.26	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3=CC=CC=C3)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BZ0T8J	1,6-Dimethyl-3-(4-phenylthiophen-2-yl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71818145	C17H13N5O2S	351.4	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3=CC(=CS3)C4=CC=CC=C4)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BZ3L1X	3-Cyclopentyl-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	71818005	C12H15N5O2	261.279	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3CCCC3)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BZF85T	3-(4-Chlorophenyl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione	Investigative	460749	C13H10ClN5O2	303.7	CN1C2=NC(=O)N(C(=O)C2=NC(=N1)C3=CC=C(C=C3)Cl)C	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	BZT7N5	8-Chloro-10-(4-methylphenyl)pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione	Investigative	930115	C18H12ClN3O2	337.8	CC1=CC=C(C=C1)N2C3=C(C=CC(=C3)Cl)C=C4C2=NC(=O)NC4=O	IC50 > 200000 nM	Non binder
T13348	AP endonuclease 1	D0P0CM	GNF-PF-2272	Investigative	460747	C8H9N5O2	207.19	CC1=NN(C2=NC(=O)N(C(=O)C2=N1)C)C	IC50 > 200000 nM	Non binder