TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T15053	Lactate dehydrogenase A	D06ACW	Adenosine monophosphate	Approved	6083	C10H14N5O7P	347.22	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	B0WQ7Z	6-Phenylnicotinic acid	Investigative	120118	C12H9NO2	199.2	C1=CC=C(C=C1)C2=NC=C(C=C2)C(=O)O	IC50 > 2000000 nM	Non binder
T15053	Lactate dehydrogenase A	B1NYH2	LDHA Inhibitor, 17	Investigative	4141306	C14H16N2O3S2	324.4	CCCSC1=NC2=C(S1)C=C(C=C2)NC(=O)CCC(=O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	B1SLC5	4-[6-[(E)-[(2-Cyanoacetyl)hydrazinylidene]methyl]pyridin-2-yl]benzoic acid	Investigative	122186812	C16H12N4O3	308.29	C1=CC(=NC(=C1)C2=CC=C(C=C2)C(=O)O)/C=N/NC(=O)CC#N	IC50 > 200000 nM	Non binder
T15053	Lactate dehydrogenase A	B43QAN	N~3~-(Ethylcarbamoyl)-N-(2-Methyl-1,3-Benzothiazol-6-Yl)-beta-Alaninamide	Investigative	56844252	C14H18N4O2S	306.39	CCNC(=O)NCCC(=O)NC1=CC2=C(C=C1)N=C(S2)C	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	B4JAN2	Methyl 6-[3-[[(2R,3R,4R,5R)-6-[2-chloro-5-methoxy-4-[[2-(5-methoxycarbonylpyridin-2-yl)sulfanylacetyl]amino]phenoxy]-2,3,4,5-tetrahydroxyhexyl]amino]-5-fluorophenyl]pyridine-3-carboxylate	Investigative	71562320	C35H36ClFN4O11S	775.2	COC1=CC(=C(C=C1NC(=O)CSC2=NC=C(C=C2)C(=O)OC)Cl)OC[C@H]([C@H]([C@@H]([C@@H](CNC3=CC(=CC(=C3)C4=NC=C(C=C4)C(=O)OC)F)O)O)O)O	IC50 > 10000000 nM	Non binder
T15053	Lactate dehydrogenase A	B4OHQ3	3-[5-[(E)-[[3-(Hydroxymethyl)benzoyl]hydrazinylidene]methyl]furan-2-yl]benzoic acid	Investigative	122186808	C20H16N2O5	364.4	C1=CC(=CC(=C1)C(=O)N/N=C/C2=CC=C(O2)C3=CC(=CC=C3)C(=O)O)CO	IC50 > 200000 nM	Non binder
T15053	Lactate dehydrogenase A	B5QC7N	N-(2-Methyl-1,3-benzothiazol-6-yl)acetamide	Investigative	596481	C10H10N2OS	206.27	CC1=NC2=C(S1)C=C(C=C2)NC(=O)C	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	B6G0JN	Chembl4213100	Investigative	145966259	C41H44O22	888.8	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O[C@H]6[C@@H]([C@](CO6)(COC(=O)/C=C/C7=CC=C(C=C7)O)O)O)O)O)O)O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	B6W2IG	2-(4-Bromanylphenoxy)propanedioic Acid	Investigative	56844251	C9H7BrO5	275.05	C1=CC(=CC=C1OC(C(=O)O)C(=O)O)Br	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	B78IYM	3-[4-[(E)-[(3,4,5-Trimethoxybenzoyl)hydrazinylidene]methyl]-1H-pyrrol-2-yl]benzoic acid	Investigative	137125271	C22H21N3O6	423.4	COC1=CC(=CC(=C1OC)OC)C(=O)N/N=C/C2=CNC(=C2)C3=CC(=CC=C3)C(=O)O	IC50 > 200000 nM	Non binder
T15053	Lactate dehydrogenase A	B7AD3H	LDHA Inhibitor, 16	Investigative	7454229	C12H12N2O3S	264.3	CC1=NC2=C(S1)C=C(C=C2)NC(=O)CCC(=O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	B8WST7	LDHA Inhibitor, 23	Investigative	57340472	C14H18N4O2S2	338.5	CCCSC1=NC2=C(S1)C=C(C=C2)NC(=O)CCNC(=O)N	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	B9FVW3	N-(2-Methyl-1,3-Benzothiazol-6-Yl)-3-Ureido-Propanamide	Investigative	47116597	C12H14N4O2S	278.33	CC1=NC2=C(S1)C=C(C=C2)NC(=O)CCNC(=O)N	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BAZP21	1-Phenyl-2H-pyrazolo[3,4-b]pyridin-3-one	Investigative	4293432	C12H9N3O	211.22	C1=CC=C(C=C1)N2C3=C(C=CC=N3)C(=O)N2	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BBH8G6	Chembl4205812	Investigative	145976873	C39H42O21	846.7	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O[C@H]6[C@@H]([C@](CO6)(COC(=O)C7=CC=CC=C7)O)O)O)O)O)O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BBY5I4	5-(2-Chlorophenyl)-1H-tetrazole	Investigative	560735	C7H5ClN4	180.59	C1=CC=C(C(=C1)C2=NNN=N2)Cl	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BDCB67	7-Benzyl-2,3-dihydroxy-6-methyl-4-propyl-naphthalene-1-carboxylic Acid	Investigative	10498042	C22H22O4	350.4	CCCC1=C(C(=C(C2=C1C=C(C(=C2)CC3=CC=CC=C3)C)C(=O)O)O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BE2WL4	3-[6-[(E)-[(3,4,5-Trimethoxybenzoyl)hydrazinylidene]methyl]pyridin-2-yl]benzoic acid	Investigative	122187851	C23H21N3O6	435.4	COC1=CC(=CC(=C1OC)OC)C(=O)N/N=C/C2=NC(=CC=C2)C3=CC(=CC=C3)C(=O)O	IC50 > 200000 nM	Non binder
T15053	Lactate dehydrogenase A	BE7B1K	4-Oxo-4-{[2-(Prop-2-En-1-Ylsulfanyl)-1,3-Benzothiazol-6-Yl]amino}butanoic Acid	Investigative	331941	C14H14N2O3S2	322.4	C=CCSC1=NC2=C(S1)C=C(C=C2)NC(=O)CCC(=O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BE7N4X	Chembl4217513	Investigative	145973103	C43H48O24	948.8	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O[C@H]6[C@@H]([C@](CO6)(COC(=O)/C=C/C7=CC(=C(C(=C7)OC)O)OC)O)O)O)O)O)O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BF2B1K	1-Hydroxy-4-(trifluoromethyl)-6-phenyl-1H-indole-2-carboxylic acid	Investigative	46893144	C16H10F3NO3	321.25	C1=CC=C(C=C1)C2=CC(=C3C=C(N(C3=C2)O)C(=O)O)C(F)(F)F	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BG2AU8	4-[5-[(E)-[(2-Cyanoacetyl)hydrazinylidene]methyl]furan-2-yl]benzoic acid	Investigative	9556853	C15H11N3O4	297.26	C1=CC(=CC=C1C2=CC=C(O2)/C=N/NC(=O)CC#N)C(=O)O	IC50 > 200000 nM	Non binder
T15053	Lactate dehydrogenase A	BGR8O4	Quercetin 3-(2G-apiosylrutinoside)	Investigative	44259159	C32H38O20	742.6	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O[C@H]6[C@@H]([C@](CO6)(CO)O)O)O)O)O)O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BJ60TQ	2-(4-Methoxybenzyl)Malonic Acid	Investigative	14392072	C11H12O5	224.21	COC1=CC=C(C=C1)CC(C(=O)O)C(=O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BK03GH	Chembl4218023	Investigative	145970499	C42H46O23	918.8	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O[C@H]6[C@@H]([C@](CO6)(COC(=O)/C=C/C7=CC(=C(C=C7)O)OC)O)O)O)O)O)O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BLEN70	2-((3,4-Dimethoxyphenyl)methyl))propanedioic Acid	Investigative	739192	C12H14O6	254.24	COC1=C(C=C(C=C1)CC(C(=O)O)C(=O)O)OC	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BN9Q4U	2-(Pyridin-3-yl)-1H-benzo[d]imidazole	Investigative	247635	C12H9N3	195.22	C1=CC=C2C(=C1)NC(=N2)C3=CN=CC=C3	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BO13UB	N-(2-Methoxyethyl)quinazolin-4-amine	Investigative	1563320	C11H13N3O	203.24	COCCNC1=NC=NC2=CC=CC=C21	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BOS5T4	N-(2-Methylamino)-1,3-Benzothiazol-6-Yl)acetamide	Investigative	45077712	C10H11N3OS	221.28	CC(=O)NC1=CC2=C(C=C1)N=C(S2)NC	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BOV8Q3	Chembl4212672	Investigative	145966736	C27H38O18	650.6	CC(=O)OC[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)COC(=O)C3=CC=CC=C3)O)O)CO)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BOWG86	Chembl4214983	Investigative	145971339	C55H86O24	1131.3	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@H]([C@@H](O[C@H]2OC(=O)[C@@]34CC[C@@]5(C(=CC[C@H]6[C@]5(CC[C@@H]7[C@@]6(C[C@@H]([C@@H]([C@@]7(C)C(=O)O)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)O)C)C)[C@@H]3CC(CC4)(C)C)C)C)OC(=O)C)O[C@H]9[C@@H]([C@](CO9)(CO)O)O)O)O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BP0Y7Q	6-({2-[(5-Chloro-2-Methoxyphenyl)amino]-2-Oxoethyl}sulfanyl)pyridine-3-Carboxylic Acid	Investigative	23605664	C15H13ClN2O4S	352.8	COC1=C(C=C(C=C1)Cl)NC(=O)CSC2=NC=C(C=C2)C(=O)O	IC50 = 770000 nM	Non binder
T15053	Lactate dehydrogenase A	BP1NU5	Nmnh	Investigative	9974249	C11H17N2O8P	336.23	C1C=CN(C=C1C(=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BPL69X	3-{5-[(Pyridine-3-carbonyl)-hydrazonomethyl]-furan-2-yl}-benzoic acid	Investigative	6882908	C18H13N3O4	335.3	C1=CC(=CC(=C1)C(=O)O)C2=CC=C(O2)/C=N/NC(=O)C3=CN=CC=C3	IC50 > 200000 nM	Non binder
T15053	Lactate dehydrogenase A	BPUG47	6-(3-Amino-5-fluorophenyl)nicotinic acid	Investigative	71562086	C12H9FN2O2	232.21	C1=CC(=NC=C1C(=O)O)C2=CC(=CC(=C2)F)N	IC50 = 1300000 nM	Non binder
T15053	Lactate dehydrogenase A	BR1Y4C	4-Hydroxynaphthalene-1-sulfonamide	Investigative	747917	C10H9NO3S	223.25	C1=CC=C2C(=C1)C(=CC=C2S(=O)(=O)N)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BSI54N	1-Hydroxy-2-naphthoic acid	Investigative	6844	C11H8O3	188.18	C1=CC=C2C(=C1)C=CC(=C2O)C(=O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	BUJI05	6-[2-[5-Chloro-4-(2,3-dihydroxypropoxy)-2-methoxyanilino]-2-oxoethyl]sulfanylpyridine-3-carboxylic acid	Investigative	71719216	C18H19ClN2O7S	442.9	COC1=CC(=C(C=C1NC(=O)CSC2=NC=C(C=C2)C(=O)O)Cl)OCC(CO)O	IC50 = 342000 nM	Non binder
T15053	Lactate dehydrogenase A	BULZ04	6-[3-(Carboxymethoxy)-5-Fluorophenyl]pyridine-3-Carboxylic Acid	Investigative	70680603	C14H10FNO5	291.23	C1=CC(=NC=C1C(=O)O)C2=CC(=CC(=C2)F)OCC(=O)O	IC50 = 2200000 nM	Non binder
T15053	Lactate dehydrogenase A	BW2LJ4	Methyl 3-[5-[(E)-(pyridine-3-carbonylhydrazinylidene)methyl]furan-2-yl]benzoate	Investigative	122186813	C19H15N3O4	349.3	COC(=O)C1=CC=CC(=C1)C2=CC=C(O2)/C=N/NC(=O)C3=CN=CC=C3	IC50 > 200000 nM	Non binder
T15053	Lactate dehydrogenase A	BXVR72	3-[5-[(E)-(1H-Indazole-5-carbonylhydrazinylidene)methyl]furan-2-yl]benzoic acid	Investigative	122186809	C20H14N4O4	374.3	C1=CC(=CC(=C1)C(=O)O)C2=CC=C(O2)/C=N/NC(=O)C3=CC4=C(C=C3)NN=C4	IC50 > 200000 nM	Non binder
T15053	Lactate dehydrogenase A	BYB27Z	Chembl4207766	Investigative	145976955	C25H36O17	608.5	C1=CC=C(C=C1)C(=O)OC[C@@H]2[C@H]([C@@H]([C@](O2)(CO)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O)O	IC50 > 500000 nM	Non binder
T15053	Lactate dehydrogenase A	D09ALJ	Rutin	Investigative	5280805	C27H30O16	610.5	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O	IC50 > 500000 nM	Non binder