TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T16514	Fatty acid synthase	D0T9TJ	Orlistat	Approved	3034010	C29H53NO5	495.7	CCCCCCCCCCC[C@@H](C[C@H]1[C@@H](C(=O)O1)CCCCCC)OC(=O)[C@H](CC(C)C)NC=O	IC50 = 203000 nM	Non binder
T16514	Fatty acid synthase	D0E4WF	METHYLTHIOADENOSINE	Terminated	439176	C11H15N5O3S	297.34	CSC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O	Ki = 1500000 nM	Non binder
T16514	Fatty acid synthase	B7YHX6	(+)-Epicatechin	Investigative	182232	C15H14O6	290.27	C1[C@@H]([C@@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O	IC50 > 1000000 nM	Non binder
T16514	Fatty acid synthase	B93GYS	Methylmethionine iodide	Investigative	145691	C6H14INO2S	291.15	C[S+](C)CC[C@@H](C(=O)O)N.[I-]	Ki = 140000000 nM	Non binder
T16514	Fatty acid synthase	BA7ZI5	5'-(Dimethylsulfonio)-5'-deoxyadenosine iodide	Investigative	45266261	C12H18IN5O3S	439.28	C[S+](C)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O.[I-]	Ki = 2500000 nM	Non binder
T16514	Fatty acid synthase	BPUA96	5'-Deoxy-5'-methylsulphonyladenosine	Investigative	44290695	C11H15N5O5S	329.34	CS(=O)(=O)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O	Ki = 220000 nM	Non binder
T16514	Fatty acid synthase	BTPN89	Methylthioadenosine sulfoxide	Investigative	165114	C11H15N5O4S	313.34	CS(=O)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O	Ki = 500000 nM	Non binder
T16514	Fatty acid synthase	D0PO8E	L-methionine	Investigative	6137	C5H11NO2S	149.21	CSCC[C@@H](C(=O)O)N	Ki > 150000000 nM	Non binder