TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T16555 P2Y purinoceptor 14 B1RUX8 Uridine-5'-Diphosphate-2-Deoxy-2-Fluoro-alpha-D-Glucose Investigative 448923 C15H23FN2O16P2 568.29 C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)F)O)O EC50 = 2500000 nM Non binder T16555 P2Y purinoceptor 14 B4CJ9M Uridine-5'-diphosphate-4-deoxy-4-fluoro-alpha-D-galactose Investigative 448872 C15H23FN2O16P2 568.29 C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)F)O)O)O)O EC50 = 567000 nM Non binder T16555 P2Y purinoceptor 14 BA5CZ6 Cyclohexyl [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate Investigative 44627698 C15H24N2O12P2 486.3 C1CCC(CC1)OP(=O)(O)OP(=O)(O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC(=O)NC3=O)O)O EC50 = 5160000 nM Non binder T16555 P2Y purinoceptor 14 BG5IO3 Uridine 5'-diphosphoric acid beta-(3-fluoro-3-deoxy-alpha-D-glucopyranosyl) ester Investigative 24858471 C15H23FN2O16P2 568.29 C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)F)O)O)O EC50 = 361000 nM Non binder T16555 P2Y purinoceptor 14 BY86BD [[(2R,3S,4R,5R)-5-(2,4-Dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5S,6S)-6-(fluoromethyl)-3,4,5-trihydroxyoxan-2-yl] hydrogen phosphate Investigative 46226455 C15H23FN2O16P2 568.29 C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CF)O)O)O)O)O EC50 = 905000 nM Non binder