TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T20401	Carbonic anhydrase II	D01WJL	Aminosalicylic Acid	Approved	4649	C7H7NO3	153.14	C1=CC(=C(C=C1N)O)C(=O)O	IC50 = 750000 nM	Non binder
T20401	Carbonic anhydrase II	D09VTE	Quinolone	Approved	6038	C9H7NO	145.16	C1=CC=C2C(=C1)C=CC(=O)N2	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	D0C8FX	Pyrithione Zinc	Approved	3005837	C10H8N2O2S2Zn	317.7	C1=CC(=S)N(C=C1)[O-].C1=CC(=S)N(C=C1)[O-].[Zn+2]	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	D0T8BA	Sulfonamide	Phase 3	5333	C6H8N2O2S	172.21	C1=CC(=CC=C1N)S(=O)(=O)N	Ki = 300000 nM	Non binder
T20401	Carbonic anhydrase II	B07THS	(1R,2S,6S,9R)-4,4-Dimethyl-6-[(sulfamoylamino)methyl]-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecane	Investigative	24853953	C10H18N2O7S	310.33	CC1(O[C@H]2[C@H]3[C@@H](CO[C@]2(O1)CNS(=O)(=O)N)OCO3)C	Ki = 300000 nM	Non binder
T20401	Carbonic anhydrase II	B0CVJ9	(2S)-5-Chloro-2-[(sulfamoylamino)methyl]-2,3-dihydro-1,4-benzodioxine	Investigative	72737581	C9H11ClN2O4S	278.71	C1[C@@H](OC2=C(O1)C(=CC=C2)Cl)CNS(=O)(=O)N	IC50 = 220000 nM	Non binder
T20401	Carbonic anhydrase II	B0I2NP	1-[(E)-(2-Chlorophenyl)methylideneamino]-3-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)urea	Investigative	44435848	C10H8ClN5OS2	313.8	C1=CC=C(C(=C1)/C=N/NC(=O)NC2=NNC(=S)S2)Cl	Ki = 412000 nM	Non binder
T20401	Carbonic anhydrase II	B0ULA9	Sodium valerate	Investigative	3669864	C5H9NaO2	124.11	CCCCC(=O)[O-].[Na+]	Ki = 257000 nM	Non binder
T20401	Carbonic anhydrase II	B0VI1Y	N-(Dipropylsulfamoyl)-N-propylpropan-1-amine	Investigative	44424363	C12H28N2O2S	264.43	CCCN(CCC)S(=O)(=O)N(CCC)CCC	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	B16GIK	6-Hydroxy-2H-chromene-2-thione	Investigative	57386887	C9H6O2S	178.21	C1=CC2=C(C=CC(=S)O2)C=C1O	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	B1ZX6I	N-[2-Oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-2-(benzoylamino)benzamide	Investigative	132495363	C24H15F3N2O4	452.4	C1=CC=C(C=C1)C(=O)NC2=CC=CC=C2C(=O)NC3=CC4=C(C=C3)C(=CC(=O)O4)C(F)(F)F	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	B23ZDY	Methanesulfonamide	Investigative	72879	CH5NO2S	95.12	CS(=O)(=O)N	Ki = 390000 nM	Non binder
T20401	Carbonic anhydrase II	B2MK1G	Di-tert-butylethane-1,2-diylbis(2-(2,2,2-trifluoroacetamido)ethylcarbamate	Investigative	12066940	C20H32F6N4O6	538.5	CC(C)(C)OC(=O)N(CCNC(=O)C(F)(F)F)CCN(CCNC(=O)C(F)(F)F)C(=O)OC(C)(C)C	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	B2P7AR	5-[4-(4-Bromo-benzenesulfonyl)-phenyl]-4-p-tolyl-4H-[1,2,4]triazole-3-thiol	Investigative	44402062	C21H16BrN3O2S2	486.4	CC1=CC=C(C=C1)N2C(=NNC2=S)C3=CC=C(C=C3)S(=O)(=O)C4=CC=C(C=C4)Br	Ki = 251000 nM	Non binder
T20401	Carbonic anhydrase II	B34OAG	2-(2-Oxochromen-7-yl)oxyethyl 4-methylbenzenesulfonate	Investigative	57386890	C18H16O6S	360.4	CC1=CC=C(C=C1)S(=O)(=O)OCCOC2=CC3=C(C=C2)C=CC(=O)O3	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	B35NTD	N,N'-Dicyclopropylsulfuric diamide	Investigative	44424362	C6H12N2O2S	176.24	C1CC1NS(=O)(=O)NC2CC2	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	B3CF2B	Methyl 3-(Butylsulfamoylamino)Propanoate	Investigative	25258363	C8H18N2O4S	238.31	CCCCNS(=O)(=O)NCCC(=O)OC	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	B3LH2D	1-(3,5-Dimethylphenyl)-3-(4-methyl-2-oxochromen-7-yl)urea	Investigative	57387136	C19H18N2O3	322.4	CC1=CC(=CC(=C1)NC(=O)NC2=CC3=C(C=C2)C(=CC(=O)O3)C)C	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	B3NI9L	4,6-Dimethyl-2H-pyran-2-one oxime	Investigative	57345662	C7H9NO2	139.15	CC1=C/C(=N\\O)/OC(=C1)C	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	B3P4BQ	2-Hydroxy-5-sulfobenzoic acid	Investigative	7322	C7H6O6S	218.19	C1=CC(=C(C=C1S(=O)(=O)O)C(=O)O)O	IC50 = 290000 nM	Non binder
T20401	Carbonic anhydrase II	B3SNF6	3-(4-(4-Chlorophenylsulfonyl)phenyl)-4-propyl-1H-1,2,4-triazole-5(4H)-thione	Investigative	42644449	C17H16ClN3O2S2	393.9	CCCN1C(=NNC1=S)C2=CC=C(C=C2)S(=O)(=O)C3=CC=C(C=C3)Cl	Ki = 618000 nM	Non binder
T20401	Carbonic anhydrase II	B4QL8W	Disodium carbamoyl phosphate	Investigative	11970596	CH2NNa2O5P	184.98	C(=O)(N)OP(=O)([O-])[O-].[Na+].[Na+]	Ki = 310000 nM	Non binder
T20401	Carbonic anhydrase II	B5GC0T	2-Mercaptoquinoline-N-oxide	Investigative	9812913	C9H7NOS	177.22	C1=CC=C2C(=C1)C=CC(=S)N2O	Ki = 950000 nM	Non binder
T20401	Carbonic anhydrase II	B5IK8N	Dicyanoaurate	Investigative	446142	C2AuN2-	249	[C-]#N.[C-]#N.[Au+]	Ki = 580000 nM	Non binder
T20401	Carbonic anhydrase II	B6E1XO	Di-tert-butylpropane-1,3-diylbis(2-(2,2,2-trifluoroacetamido)-ethylcarbamate	Investigative	12066941	C21H34F6N4O6	552.5	CC(C)(C)OC(=O)N(CCCN(CCNC(=O)C(F)(F)F)C(=O)OC(C)(C)C)CCNC(=O)C(F)(F)F	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	B6JEQ4	1-Mesyl-5-bromouracil	Investigative	11482579	C5H5BrN2O4S	269.08	CS(=O)(=O)N1C=C(C(=O)NC1=O)Br	Ki = 645000 nM	Non binder
T20401	Carbonic anhydrase II	B6NXA7	Heptafluoroniobium(2-)	Investigative	4712722	F7Nb-2	225.895	F[Nb-2](F)(F)(F)(F)(F)F	Ki = 600000 nM	Non binder
T20401	Carbonic anhydrase II	B6T5RQ	5-Methylquinoline-8-thiol	Investigative	12507616	C10H9NS	175.25	CC1=C2C=CC=NC2=C(C=C1)S	IC50 > 200000 nM	Non binder
T20401	Carbonic anhydrase II	B71NEW	N,N,N',N'-Tetrabutylsulfamide	Investigative	44424364	C16H36N2O2S	320.5	CCCCN(CCCC)S(=O)(=O)N(CCCC)CCCC	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	B7LEZ2	1-[(E)-1-(4-Methoxyphenyl)ethylideneamino]-3-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)urea	Investigative	44435861	C12H13N5O2S2	323.4	C/C(=N\\NC(=O)NC1=NNC(=S)S1)/C2=CC=C(C=C2)OC	Ki = 346000 nM	Non binder
T20401	Carbonic anhydrase II	B7OHR2	(-)-Dihydroguaiaretic acid	Investigative	11602375	C20H26O4	330.4	C[C@H](CC1=CC(=C(C=C1)O)OC)[C@H](C)CC2=CC(=C(C=C2)O)OC	Ki = 230000 nM	Non binder
T20401	Carbonic anhydrase II	B8B7AS	Imidodisulfuric acid	Investigative	162152	H3NO6S2	177.16	N(S(=O)(=O)O)S(=O)(=O)O	Ki = 760000 nM	Non binder
T20401	Carbonic anhydrase II	B8J1KR	2-[(4-Fluorobenzoyl)amino]-N-(4-methyl-2-oxochromen-7-yl)benzamide	Investigative	134154625	C24H17FN2O4	416.4	CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C3=CC=CC=C3NC(=O)C4=CC=C(C=C4)F	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	B8P0IO	Tert-butyl 4-methyl-2-oxo-2H-chromen-7-ylcarbamate	Investigative	57387137	C15H17NO4	275.3	CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)OC(C)(C)C	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	B94CVN	1-[(E)-(4-Hydroxy-3-methoxyphenyl)methylideneamino]-3-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)urea	Investigative	136104491	C11H11N5O3S2	325.4	COC1=C(C=CC(=C1)/C=N/NC(=O)NC2=NNC(=S)S2)O	Ki = 386000 nM	Non binder
T20401	Carbonic anhydrase II	B9IRF2	trans-(1S(R),2S(R))-2-Hydroxycyclohexyl nitrate	Investigative	10964817	C6H11NO4	161.16	C1CC[C@@H]([C@H](C1)O)O[N+](=O)[O-]	IC50 = 560000 nM	Non binder
T20401	Carbonic anhydrase II	B9PUL1	(2S)-2-[[(Tert-Butyloxycarbonyl)sulfamoyl]amino]propionic acid methyl ester	Investigative	15014351	C9H18N2O6S	282.32	C[C@@H](C(=O)OC)NS(=O)(=O)NC(=O)OC(C)(C)C	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	B9URB3	1-[(E)-1-(4-Hydroxyphenyl)ethylideneamino]-3-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)urea	Investigative	136104494	C11H11N5O2S2	309.4	C/C(=N\\NC(=O)NC1=NNC(=S)S1)/C2=CC=C(C=C2)O	Ki = 350000 nM	Non binder
T20401	Carbonic anhydrase II	BAP2U0	Sodium 3-Methylvalerate	Investigative	54584941	C6H11NaO2	138.14	CCC(C)CC(=O)[O-].[Na+]	Ki = 281000 nM	Non binder
T20401	Carbonic anhydrase II	BB08IA	4-Methylquinoline-8-thiol	Investigative	12344252	C10H9NS	175.25	CC1=C2C=CC=C(C2=NC=C1)S	IC50 > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BB38GO	5-(4-Benzenesulfonyl-phenyl)-4-butyl-4H-[1,2,4]triazole-3-thiol	Investigative	10926842	C18H19N3O2S2	373.5	CCCCN1C(=NNC1=S)C2=CC=C(C=C2)S(=O)(=O)C3=CC=CC=C3	Ki = 604000 nM	Non binder
T20401	Carbonic anhydrase II	BBTJ03	Pyrithione	Investigative	1570	C5H5NOS	127.17	C1=CC(=S)N(C=C1)O	Ki = 510000 nM	Non binder
T20401	Carbonic anhydrase II	BBWV30	(1R,2S,6S,9R)-4,4-Dimethyl-6-[(sulfamoylamino)methyl]spiro[3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecane-11,1'-cyclohexane]	Investigative	24853954	C15H26N2O7S	378.4	CC1(O[C@H]2[C@H]3[C@@H](CO[C@]2(O1)CNS(=O)(=O)N)OC4(O3)CCCCC4)C	Ki > 300000 nM	Non binder
T20401	Carbonic anhydrase II	BC29YW	Fluorosulfonic acid	Investigative	24603	FHO3S	100.07	OS(=O)(=O)F	Ki = 460000 nM	Non binder
T20401	Carbonic anhydrase II	BCP1M2	N-(4-Methyl-2-oxochromen-7-yl)acetamide	Investigative	927433	C12H11NO3	217.22	CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BCT5Y2	Sodium argentous cyanide	Investigative	167985	C2AgN2Na	182.89	[C-]#N.[C-]#N.[Na+].[Ag+]	Ki = 760000 nM	Non binder
T20401	Carbonic anhydrase II	BDC13X	2-[(4-Chlorobenzoyl)amino]-N-(4-methyl-2-oxochromen-7-yl)benzamide	Investigative	134152281	C24H17ClN2O4	432.9	CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C3=CC=CC=C3NC(=O)C4=CC=C(C=C4)Cl	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	BDG7U3	2-[(4-Chlorobenzoyl)amino]-N-[2-oxo-4-(trifluoromethyl)chromen-7-yl]benzamide	Investigative	134155483	C24H14ClF3N2O4	486.8	C1=CC=C(C(=C1)C(=O)NC2=CC3=C(C=C2)C(=CC(=O)O3)C(F)(F)F)NC(=O)C4=CC=C(C=C4)Cl	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	BDS41H	Disodium maleate	Investigative	6364608	C4H2Na2O4	160.04	C(=C\\C(=O)[O-])\\C(=O)[O-].[Na+].[Na+]	Ki = 989000 nM	Non binder
T20401	Carbonic anhydrase II	BE71JG	Chloric acid	Investigative	19654	ClHO3	84.46	OCl(=O)=O	Ki = 850000 nM	Non binder
T20401	Carbonic anhydrase II	BE7PQ2	Sodium isobutyrate	Investigative	23674499	C4H7NaO2	110.09	CC(C)C(=O)[O-].[Na+]	Ki = 350000 nM	Non binder
T20401	Carbonic anhydrase II	BEFR35	Coumaphos	Investigative	2871	C14H16ClO5PS	362.8	CCOP(=S)(OCC)OC1=CC2=C(C=C1)C(=C(C(=O)O2)Cl)C	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BF16TG	7-(2-Fluoroethyloxy)-coumarin	Investigative	57387135	C11H9FO3	208.18	C1=CC(=CC2=C1C=CC(=O)O2)OCCF	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BFU40J	Methyl 3-[(2-Hydroxyphenoxy)Sulfonylamino]Propanoate	Investigative	25258358	C10H13NO6S	275.28	COC(=O)CCNS(=O)(=O)OC1=CC=CC=C1O	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BFUO83	trans-(1S(R),8S(R),Z)-8-Hydroxycyclooct-4-enyl nitrate	Investigative	45266944	C8H13NO4	187.19	C/1C[C@@H]([C@H](CC/C=C1)O[N+](=O)[O-])O	IC50 = 243000 nM	Non binder
T20401	Carbonic anhydrase II	BG7TH5	(1R,2S,6S,9R,11R)-4,4,11-Trimethyl-6-[(sulfamoylamino)methyl]-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecane	Investigative	24829374	C11H20N2O7S	324.35	C[C@@H]1O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)CNS(=O)(=O)N	Ki = 300000 nM	Non binder
T20401	Carbonic anhydrase II	BH4J6A	N-(2,2-Dimethyl-1,3-dioxolan-4-ylmethyl)sulfamide	Investigative	11521331	C6H14N2O4S	210.25	CC1(OCC(O1)CNS(=O)(=O)N)C	Ki = 408000 nM	Non binder
T20401	Carbonic anhydrase II	BI6H1R	2,4-Dihydroxy-6-nitroquinazoline	Investigative	816982	C8H5N3O4	207.14	C1=CC2=C(C=C1[N+](=O)[O-])C(=O)NC(=O)N2	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	BIU4M5	1-Acetyl-5-bromopyrimidine-2,4-dione	Investigative	122185233	C6H5BrN2O3	233.02	CC(=O)N1C=C(C(=O)NC1=O)Br	Ki = 778500 nM	Non binder
T20401	Carbonic anhydrase II	BIYO50	N,N'-Sulfonyl Bis-L-alanine Dimethyl Ester	Investigative	18710120	C8H16N2O6S	268.29	C[C@@H](C(=O)OC)NS(=O)(=O)N[C@@H](C)C(=O)OC	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BK2S7Q	1-Hydroxy-5-(Trifluoromethyl)pyridine-2(1h)-Thione	Investigative	9964347	C6H4F3NOS	195.16	C1=CC(=S)N(C=C1C(F)(F)F)O	Ki = 270000 nM	Non binder
T20401	Carbonic anhydrase II	BKF2Q1	trans-(1S(R),6S(R))-6-Hydroxycyclohex-3-enyl nitrate	Investigative	45268767	C6H9NO4	159.14	C1C=CC[C@@H]([C@H]1O)O[N+](=O)[O-]	IC50 = 790000 nM	Non binder
T20401	Carbonic anhydrase II	BL03ET	1-Hydroxy-5-Methylpyridine-2(1h)-Thione	Investigative	9942169	C6H7NOS	141.19	CC1=CN(C(=S)C=C1)O	Ki = 260000 nM	Non binder
T20401	Carbonic anhydrase II	BL6R2E	(1R,2S,6S,9R)-4,4-Dimethyl-6-[(sulfamoylamino)methyl]spiro[3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecane-11,1'-cyclopentane]	Investigative	24853952	C14H24N2O7S	364.42	CC1(O[C@H]2[C@H]3[C@@H](CO[C@]2(O1)CNS(=O)(=O)N)OC4(O3)CCCC4)C	Ki > 300000 nM	Non binder
T20401	Carbonic anhydrase II	BM35ZE	2-Phenyl-N-(2-phenylethylsulfamoyl)ethanamine	Investigative	14787919	C16H20N2O2S	304.4	C1=CC=C(C=C1)CCNS(=O)(=O)NCCC2=CC=CC=C2	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BM7QK4	Sodium 4-Methylvalerate	Investigative	23672490	C6H11NaO2	138.14	CC(C)CCC(=O)[O-].[Na+]	Ki = 320000 nM	Non binder
T20401	Carbonic anhydrase II	BM8C1W	Tetraborsaure	Investigative	4321567	B4H2O7	157.3	B(=O)OB(O)OB(O)OB=O	Ki = 950000 nM	Non binder
T20401	Carbonic anhydrase II	BM8Z9E	Methyl 3-[(3-methoxy-3-oxopropyl)sulfamoylamino]propanoate	Investigative	25258360	C8H16N2O6S	268.29	COC(=O)CCNS(=O)(=O)NCCC(=O)OC	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BMWO81	1-[(E)-(4-Bromophenyl)methylideneamino]-3-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)urea	Investigative	23661710	C10H8BrN5OS2	358.2	C1=CC(=CC=C1/C=N/NC(=O)NC2=NNC(=S)S2)Br	Ki = 360000 nM	Non binder
T20401	Carbonic anhydrase II	BO90EF	1-[(E)-(4-Methoxyphenyl)methylideneamino]-3-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)urea	Investigative	44435846	C11H11N5O2S2	309.4	COC1=CC=C(C=C1)/C=N/NC(=O)NC2=NNC(=S)S2	Ki = 350000 nM	Non binder
T20401	Carbonic anhydrase II	BOB1D5	2-Benzamido-N-(4-methyl-2-oxochromen-7-yl)benzamide	Investigative	134141819	C24H18N2O4	398.4	CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C3=CC=CC=C3NC(=O)C4=CC=CC=C4	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	BOB23T	4-Hydroxyquinazoline	Investigative	135408753	C8H6N2O	146.15	C1=CC=C2C(=C1)C(=O)NC=N2	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	BPE40U	(3S)-5-Methoxy-3-[(sulfamoylamino)methyl]-2,3-dihydro-1,4-benzodioxine	Investigative	72737586	C10H14N2O5S	274.3	COC1=CC=CC2=C1O[C@H](CO2)CNS(=O)(=O)N	IC50 = 300000 nM	Non binder
T20401	Carbonic anhydrase II	BPV1B8	4-Butyl-5-[4-(4-chloro-benzenesulfonyl)-phenyl]-4H-[1,2,4]triazole-3-thiol	Investigative	11112315	C18H18ClN3O2S2	407.9	CCCCN1C(=NNC1=S)C2=CC=C(C=C2)S(=O)(=O)C3=CC=C(C=C3)Cl	Ki = 227000 nM	Non binder
T20401	Carbonic anhydrase II	BQ70UH	1-[(E)-(2-Nitrophenyl)methylideneamino]-3-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)urea	Investigative	44435853	C10H8N6O3S2	324.3	C1=CC=C(C(=C1)/C=N/NC(=O)NC2=NNC(=S)S2)[N+](=O)[O-]	Ki = 433000 nM	Non binder
T20401	Carbonic anhydrase II	BQP57S	8-Mercaptoquinoline	Investigative	96028	C9H7NS	161.23	C1=CC2=C(C(=C1)S)N=CC=C2	IC50 > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BRMA78	Dioxido(oxo)tin	Investigative	25502	O3Sn-2	166.71	[O-][Sn](=O)[O-]	Ki = 830000 nM	Non binder
T20401	Carbonic anhydrase II	BS2H3U	N-(1H-Indol-3-ylmethyl)sulfamide	Investigative	44597633	C9H11N3O2S	225.27	C1=CC=C2C(=C1)C(=CN2)CNS(=O)(=O)N	IC50 = 300000 nM	Non binder
T20401	Carbonic anhydrase II	BTFE12	P-Toluenesulfonic acid	Investigative	6101	C7H8O3S	172.2	CC1=CC=C(C=C1)S(=O)(=O)O	Ki = 460000 nM	Non binder
T20401	Carbonic anhydrase II	BTKP31	1-[(E)-(3-Bromophenyl)methylideneamino]-3-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)urea	Investigative	44435850	C10H8BrN5OS2	358.2	C1=CC(=CC(=C1)Br)/C=N/NC(=O)NC2=NNC(=S)S2	Ki = 235750 nM	Non binder
T20401	Carbonic anhydrase II	BTN45D	N,N'-Sulfonyl Bis-L-valine Dimethyl Ester	Investigative	12051191	C12H24N2O6S	324.4	CC(C)[C@@H](C(=O)OC)NS(=O)(=O)N[C@@H](C(C)C)C(=O)OC	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BUN2Z4	Sodium oxalate	Investigative	6125	C2Na2O4	134	C(=O)(C(=O)[O-])[O-].[Na+].[Na+]	Ki = 990000 nM	Non binder
T20401	Carbonic anhydrase II	BUW28P	Sodium pyrovanadate(V)	Investigative	4608376	O7V2-4	213.88	[O-][V](=O)([O-])O[V](=O)([O-])[O-]	Ki = 570000 nM	Non binder
T20401	Carbonic anhydrase II	BV29IP	Tert-butyl N-(dipropylsulfamoyl)carbamate	Investigative	44424366	C11H24N2O4S	280.39	CCCN(CCC)S(=O)(=O)NC(=O)OC(C)(C)C	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BVLY80	(Dihydroxy(oxo)vanadio)oxy-dihydroxy-oxovanadium	Investigative	5462815	H4O7V2	217.91	O[V](=O)(O)O[V](=O)(O)O	Ki = 570000 nM	Non binder
T20401	Carbonic anhydrase II	BWD4G5	4-Methoxycinnamic acid	Investigative	699414	C10H10O3	178.18	COC1=CC=C(C=C1)/C=C/C(=O)O	IC50 = 760000 nM	Non binder
T20401	Carbonic anhydrase II	BWN1X0	7-(2-Hydroxyethyloxy)coumarin	Investigative	22706805	C11H10O4	206.19	C1=CC(=CC2=C1C=CC(=O)O2)OCCO	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BWOR72	5-[4-(4-Bromo-benzenesulfonyl)-phenyl]-4-m-tolyl-4H-[1,2,4]triazole-3-thiol	Investigative	44401926	C21H16BrN3O2S2	486.4	CC1=CC(=CC=C1)N2C(=NNC2=S)C3=CC=C(C=C3)S(=O)(=O)C4=CC=C(C=C4)Br	Ki = 301000 nM	Non binder
T20401	Carbonic anhydrase II	BWS8H6	Perrhenate	Investigative	139584	O4Re-	250.2	[O-][Re](=O)(=O)=O	Ki = 750000 nM	Non binder
T20401	Carbonic anhydrase II	BX0U3S	2-[(4-Fluorobenzoyl)amino]-N-[2-oxo-4-(trifluoromethyl)chromen-7-yl]benzamide	Investigative	134133137	C24H14F4N2O4	470.4	C1=CC=C(C(=C1)C(=O)NC2=CC3=C(C=C2)C(=CC(=O)O3)C(F)(F)F)NC(=O)C4=CC=C(C=C4)F	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	BX0Y9J	3-(4-(4-Bromophenylsulfonyl)phenyl)-4-propyl-1H-1,2,4-triazole-5(4H)-thione	Investigative	42644450	C17H16BrN3O2S2	438.4	CCCN1C(=NNC1=S)C2=CC=C(C=C2)S(=O)(=O)C3=CC=C(C=C3)Br	Ki = 382000 nM	Non binder
T20401	Carbonic anhydrase II	BX5QZ6	Tetrachloroplatinate(2-)	Investigative	61441	Cl4Pt-2	336.9	Cl[Pt-2](Cl)(Cl)Cl	Ki = 510000 nM	Non binder
T20401	Carbonic anhydrase II	BXE10F	5-(4-Benzenesulfonyl-phenyl)-4-propyl-4H-[1,2,4]triazole-3-thiol	Investigative	42643988	C17H17N3O2S2	359.5	CCCN1C(=NNC1=S)C2=CC=C(C=C2)S(=O)(=O)C3=CC=CC=C3	Ki = 276000 nM	Non binder
T20401	Carbonic anhydrase II	BY1A4M	Dihydroxidodioxidotellurium	Investigative	61609	H2O4Te	193.6	O[Te](=O)(=O)O	Ki = 920000 nM	Non binder
T20401	Carbonic anhydrase II	BY4X6B	4-Sulfosalicylic acid	Investigative	164000	C7H6O6S	218.19	C1=CC(=C(C=C1S(=O)(=O)O)O)C(=O)O	IC50 = 720000 nM	Non binder
T20401	Carbonic anhydrase II	BY68EN	(NZ)-N-chromen-2-ylidenehydroxylamine	Investigative	6537802	C9H7NO2	161.16	C1=CC=C2C(=C1)C=C/C(=N/O)/O2	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	BZ18TA	N1,N2-(2-(2,2,2-Trifluoroacetamido)ethyl)ethane-1,2-diaminium Trifluoroacetate	Investigative	15938557	C10H16F6N4O2	338.25	C(CNCCNC(=O)C(F)(F)F)NCCNC(=O)C(F)(F)F	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	BZ4CR5	4-[5-(Methyloxycarbonyl)-pentylamino]-1-hydroxy-2(1H)-pyrimidinone	Investigative	46891018	C11H17N3O4	255.27	COC(=O)CCCCCNC1=NC(=O)N(C=C1)O	Ki = 270000 nM	Non binder
T20401	Carbonic anhydrase II	BZ65UN	N#C[Cu-]C#N	Investigative	60167587	C2CuN2-	115.58	[C-]#N.[C-]#N.[Cu+]	Ki = 560000 nM	Non binder
T20401	Carbonic anhydrase II	BZ7MR5	1-Hydroxy-4,6-Dimethylpyridine-2(1h)-Thione	Investigative	9898889	C7H9NOS	155.22	CC1=CC(=S)N(C(=C1)C)O	Ki = 950000 nM	Non binder
T20401	Carbonic anhydrase II	BZ7TQ6	N-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-2-nitro-benzenesulfonamide	Investigative	44401951	C8H6N4O4S3	318.4	C1=CC=C(C(=C1)[N+](=O)[O-])S(=O)(=O)NC2=NNC(=S)S2	Ki = 230000 nM	Non binder
T20401	Carbonic anhydrase II	BZB6P2	N-{[(3As,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl}sulfamide	Investigative	10712038	C12H22N2O7S	338.38	CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)CNS(=O)(=O)N)C	Ki = 340000 nM	Non binder
T20401	Carbonic anhydrase II	BZOJ57	1-[(E)-Benzylideneamino]-3-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)urea	Investigative	44435843	C10H9N5OS2	279.3	C1=CC=C(C=C1)/C=N/NC(=O)NC2=NNC(=S)S2	Ki = 354000 nM	Non binder
T20401	Carbonic anhydrase II	D01BUB	2,5-difluorophenol	Investigative	94952	C6H4F2O	130.09	C1=CC(=C(C=C1F)O)F	Ki = 870000 nM	Non binder
T20401	Carbonic anhydrase II	D03MJM	Trans-(R(S))-2-Hydroxy-1-phenylethyl nitrate	Investigative	45273020	C8H9NO4	183.16	C1=CC=C(C=C1)[C@H](CO)O[N+](=O)[O-]	IC50 = 632000 nM	Non binder
T20401	Carbonic anhydrase II	D06XVV	BENZOYLENUREA	Investigative	64048	C8H6N2O2	162.15	C1=CC=C2C(=C1)C(=O)NC(=O)N2	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	D07MTM	4-AMINOPHENOL	Investigative	403	C6H7NO	109.13	C1=CC(=CC=C1N)O	Ki = 752000 nM	Non binder
T20401	Carbonic anhydrase II	D07PZQ	L-serine-O-phosphate	Investigative	68841	C3H8NO6P	185.07	C([C@@H](C(=O)O)N)OP(=O)(O)O	Ki = 420000 nM	Non binder
T20401	Carbonic anhydrase II	D07VXX	2-(benzyloxyamino)-N-hydroxy-3-methylpentanamide	Investigative	16721024	C13H20N2O3	252.31	CCC(C)C(C(=O)NO)NOCC1=CC=CC=C1	Ki = 267000 nM	Non binder
T20401	Carbonic anhydrase II	D0B0SD	Propionate	Investigative	104745	C3H5O2-	73.07	CCC(=O)[O-]	Ki = 960000 nM	Non binder
T20401	Carbonic anhydrase II	D0F7QZ	Styrylboronic acid	Investigative	5702628	C8H9BO2	147.97	B(/C=C/C1=CC=CC=C1)(O)O	Ki = 534000 nM	Non binder
T20401	Carbonic anhydrase II	D0FD8G	2-(biphenyl-4-yl)vinylboronic acid	Investigative	6011033	C14H13BO2	224.06	B(/C=C/C1=CC=C(C=C1)C2=CC=CC=C2)(O)O	Ki = 373000 nM	Non binder
T20401	Carbonic anhydrase II	D0H3NS	2-oxo-2H-chromene-3-carboxylic acid	Investigative	10752	C10H6O4	190.15	C1=CC=C2C(=C1)C=C(C(=O)O2)C(=O)O	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	D0L5XK	7-AMINO-4-METHYL-CHROMEN-2-ONE	Investigative	92249	C10H9NO2	175.18	CC1=CC(=O)OC2=C1C=CC(=C2)N	Ki > 200000 nM	Non binder
T20401	Carbonic anhydrase II	D0Q2XB	3,5-difluorophenol	Investigative	75928	C6H4F2O	130.09	C1=C(C=C(C=C1F)F)O	Ki = 339790 nM	Non binder
T20401	Carbonic anhydrase II	D0U4BB	HERNIARIN	Investigative	10748	C10H8O3	176.17	COC1=CC2=C(C=C1)C=CC(=O)O2	Ki > 500000 nM	Non binder
T20401	Carbonic anhydrase II	D0X0RE	4-methylstyrylboronic acid	Investigative	6019835	C9H11BO2	162	B(/C=C/C1=CC=C(C=C1)C)(O)O	Ki = 617000 nM	Non binder