TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T20514	Delta-aminolevulinic acid dehydratase	B0OV9F	5-Methyl-5-aminolevulinic acid	Investigative	21158826; 71813335	C6H11NO3	145.16	CC(C(=O)CCC(=O)O)N	Ki = 200000000 nM	Non binder
T20514	Delta-aminolevulinic acid dehydratase	B0RW5L	2-[3-(Trifluoromethyl)benzoyl]-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine-10-carboxylic acid	Investigative	3307674	C21H15F3N2O3	400.3	C1CN(CC2=C(C3=CC=CC=C3N=C21)C(=O)O)C(=O)C4=CC(=CC=C4)C(F)(F)F	IC50 = 500000 nM	Non binder
T20514	Delta-aminolevulinic acid dehydratase	B3GT6B	1-Methyl-1H-benzimidazole-5-carboxylic acid	Investigative	4913063	C9H8N2O2	176.17	CN1C=NC2=C1C=CC(=C2)C(=O)O	IC50 = 500000 nM	Non binder
T20514	Delta-aminolevulinic acid dehydratase	B3V8WU	1-[3-(Trifluoromethyl)benzyl]-2-[2-[(2-thienylcarbonyl)amino]ethyl]-1H-benzoimidazole-5-carboxylic acid	Investigative	42817381	C23H18F3N3O3S	473.5	C1=CC(=CC(=C1)C(F)(F)F)CN2C3=C(C=C(C=C3)C(=O)O)N=C2CCNC(=O)C4=CC=CS4	IC50 = 739000 nM	Non binder
T20514	Delta-aminolevulinic acid dehydratase	B6NC4M	2-[2-(Thiophene-2-carbonylamino)ethyl]-3-[[3-(trifluoromethyl)phenyl]methyl]benzimidazole-4-carboxylic acid	Investigative	90643855	C23H18F3N3O3S	473.5	C1=CC(=CC(=C1)C(F)(F)F)CN2C(=NC3=CC=CC(=C32)C(=O)O)CCNC(=O)C4=CC=CS4	IC50 = 500000 nM	Non binder
T20514	Delta-aminolevulinic acid dehydratase	B83VNS	2-[2-(Thiophene-2-carbonylamino)ethyl]-1-[[3-(trifluoromethyl)phenyl]methyl]benzimidazole-4-carboxylic acid	Investigative	90643854	C23H18F3N3O3S	473.5	C1=CC(=CC(=C1)C(F)(F)F)CN2C3=CC=CC(=C3N=C2CCNC(=O)C4=CC=CS4)C(=O)O	IC50 = 500000 nM	Non binder
T20514	Delta-aminolevulinic acid dehydratase	BHC46M	1-Benzyl-1,3-benzodiazole-5-carboxylic acid	Investigative	29559943	C15H12N2O2	252.27	C1=CC=C(C=C1)CN2C=NC3=C2C=CC(=C3)C(=O)O	IC50 = 213000 nM	Non binder
T20514	Delta-aminolevulinic acid dehydratase	BJ1BW8	2-[2-(Thiophene-2-carbonylamino)ethyl]-3-[[3-(trifluoromethyl)phenyl]methyl]benzimidazole-5-carboxylic acid	Investigative	90643853	C23H18F3N3O3S	473.5	C1=CC(=CC(=C1)C(F)(F)F)CN2C3=C(C=CC(=C3)C(=O)O)N=C2CCNC(=O)C4=CC=CS4	IC50 = 500000 nM	Non binder
T20514	Delta-aminolevulinic acid dehydratase	BP82AV	1-(4-Fluorobenzyl)-2-oxo-3-(2-pyrrolidin-1-ylethyl)-2,3-dihydro-1H-benzimidazole-5-carboxylic acid	Investigative	50965913	C21H22FN3O3	383.4	C1CCN(C1)CCN2C3=C(C=CC(=C3)C(=O)O)N(C2=O)CC4=CC=C(C=C4)F	IC50 > 1000000 nM	Non binder
T20514	Delta-aminolevulinic acid dehydratase	BSUV87	2-[2-(Thiophene-2-carbonylamino)ethyl]-3H-benzimidazole-5-carboxylic acid	Investigative	90643851	C15H13N3O3S	315.3	C1=CSC(=C1)C(=O)NCCC2=NC3=C(N2)C=C(C=C3)C(=O)O	IC50 = 500000 nM	Non binder
T20514	Delta-aminolevulinic acid dehydratase	BWE0Y3	2-[2-(Thiophene-2-carbonylamino)ethyl]-1-[[4-(trifluoromethyl)phenyl]methyl]benzimidazole-5-carboxylic acid	Investigative	90643856	C23H18F3N3O3S	473.5	C1=CSC(=C1)C(=O)NCCC2=NC3=C(N2CC4=CC=C(C=C4)C(F)(F)F)C=CC(=C3)C(=O)O	IC50 = 637000 nM	Non binder
T20514	Delta-aminolevulinic acid dehydratase	BX2G6K	1H-Benzimidazole-5-carboxylic acid	Investigative	459456	C8H6N2O2	162.15	C1=CC2=C(C=C1C(=O)O)NC=N2	IC50 = 511000 nM	Non binder
T20514	Delta-aminolevulinic acid dehydratase	BX34DM	1-[(3-Methylphenyl)methyl]benzimidazole-5-carboxylic acid	Investigative	28547001	C16H14N2O2	266.29	CC1=CC(=CC=C1)CN2C=NC3=C2C=CC(=C3)C(=O)O	IC50 = 222000 nM	Non binder