TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T21945	Norepinephrine transporter	D07HQC	Modafinil	Approved	4236	C15H15NO2S	273.4	C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC(=O)N	IC50 = 283600 nM	Non binder
T21945	Norepinephrine transporter	D0R6LF	Citalopram derivative 1	Patented	2771	C20H21FN2O	324.4	CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F	Ki > 1000000 nM	Non binder
T21945	Norepinephrine transporter	B09TKB	Methyl 2-(4-tert-butylphenyl)cyclohex-1-enecarboxylate	Investigative	44429205	C18H24O2	272.4	CC(C)(C)C1=CC=C(C=C1)C2=C(CCCC2)C(=O)OC	Ki = 1100000 nM	Non binder
T21945	Norepinephrine transporter	B0GBP4	2-(Benzhydrylsulfinylmethyl)-4-methoxy-6-methylpyrimidine	Investigative	137640164	C20H20N2O2S	352.5	CC1=CC(=NC(=N1)CS(=O)C(C2=CC=CC=C2)C3=CC=CC=C3)OC	IC50 = 227500 nM	Non binder
T21945	Norepinephrine transporter	B0KCD3	(2-(3,4-Dichlorophenyl)cyclopent-1-enyl)(morpholino)methanone	Investigative	44443873	C16H17Cl2NO2	326.2	C1CC(=C(C1)C(=O)N2CCOCC2)C3=CC(=C(C=C3)Cl)Cl	Ki = 300000 nM	Non binder
T21945	Norepinephrine transporter	B0L1TW	Methyl 2-(3-chlorophenyl)cyclohex-1-enecarboxylate	Investigative	44429202	C14H15ClO2	250.72	COC(=O)C1=C(CCCC1)C2=CC(=CC=C2)Cl	Ki = 339000 nM	Non binder
T21945	Norepinephrine transporter	B1VG9T	(2S,3S,4S,5R,6S)-6-[1-[(2S,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxyoxan-2-yl]oxy-5-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]naphthalen-2-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid	Investigative	70681491	C30H35NO15S	681.7	CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=C2C=CC(=C3O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)C(=O)O)O)O)O	Ki > 10000000 nM	Non binder
T21945	Norepinephrine transporter	B2L4GB	(2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-[2-methoxy-5-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]naphthalen-1-yl]oxyoxane-2-carboxylic acid	Investigative	70683608	C25H29NO9S	519.6	CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=C2C=CC(=C3O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)OC	Ki > 10000000 nM	Non binder
T21945	Norepinephrine transporter	B2MFZ7	Methyl 2-(4-(trifluoromethoxy)phenyl)cyclohexanecarboxylate	Investigative	44429395	C15H17F3O3	302.29	COC(=O)[C@@H]1CCCC[C@@H]1C2=CC=C(C=C2)OC(F)(F)F	Ki = 719000 nM	Non binder
T21945	Norepinephrine transporter	B3NIT7	Methyl 2-(4-hydroxyphenyl)cyclohex-1-enecarboxylate	Investigative	44429212	C14H16O3	232.27	COC(=O)C1=C(CCCC1)C2=CC=C(C=C2)O	Ki = 499000 nM	Non binder
T21945	Norepinephrine transporter	B4QM5H	Methyl 2-(3-(trifluoromethyl)phenyl)cyclohex-1-enecarboxylate	Investigative	44429209	C15H15F3O2	284.27	COC(=O)C1=C(CCCC1)C2=CC(=CC=C2)C(F)(F)F	Ki = 2110000 nM	Non binder
T21945	Norepinephrine transporter	B5VWF6	Methyl 2-(4-chlorophenyl)cyclohex-1-enecarboxylate	Investigative	44429201	C14H15ClO2	250.72	COC(=O)C1=C(CCCC1)C2=CC=C(C=C2)Cl	Ki = 314000 nM	Non binder
T21945	Norepinephrine transporter	B7RFB6	4-Hydroxy Duloxetine b-D-Glucuronide	Investigative	29981513	C24H27NO8S	489.5	CNCC[C@@H](C1=CC=CS1)OC2=CC=C(C3=CC=CC=C32)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O	Ki > 10000000 nM	Non binder
T21945	Norepinephrine transporter	B87XMC	Methyl 2-(biphenyl-4-yl)cyclohex-1-enecarboxylate	Investigative	44429204	C20H20O2	292.4	COC(=O)C1=C(CCCC1)C2=CC=C(C=C2)C3=CC=CC=C3	Ki = 215000 nM	Non binder
T21945	Norepinephrine transporter	B94ZVL	Methyl 2-(3-aminophenyl)cyclopent-1-enecarboxylate	Investigative	44429198	C13H15NO2	217.26	COC(=O)C1=C(CCC1)C2=CC(=CC=C2)N	Ki = 247000 nM	Non binder
T21945	Norepinephrine transporter	B9RYC1	Methyl 2-(4-acetylphenyl)cyclopent-1-enecarboxylate	Investigative	44429197	C15H16O3	244.28	CC(=O)C1=CC=C(C=C1)C2=C(CCC2)C(=O)OC	Ki = 240000 nM	Non binder
T21945	Norepinephrine transporter	BB6E4L	Methyl 2-(3-(trifluoromethyl)phenyl)cyclohexanecarboxylate	Investigative	44429397	C15H17F3O2	286.29	COC(=O)[C@@H]1CCCC[C@@H]1C2=CC(=CC=C2)C(F)(F)F	Ki = 991000 nM	Non binder
T21945	Norepinephrine transporter	BC36LD	Methyl 2-(4-(trifluoromethoxy)phenyl)cyclohex-1-enecarboxylate	Investigative	44429206	C15H15F3O3	300.27	COC(=O)C1=C(CCCC1)C2=CC=C(C=C2)OC(F)(F)F	Ki = 2540000 nM	Non binder
T21945	Norepinephrine transporter	BD0OG2	Methyl 2-phenylcyclohexene-1-carboxylate	Investigative	44429207	C14H16O2	216.27	COC(=O)C1=C(CCCC1)C2=CC=CC=C2	Ki = 2500000 nM	Non binder
T21945	Norepinephrine transporter	BE04LO	Methyl 2-(4-tert-butylphenyl)cyclopent-1-enecarboxylate	Investigative	44429194	C17H22O2	258.35	CC(C)(C)C1=CC=C(C=C1)C2=C(CCC2)C(=O)OC	Ki = 789000 nM	Non binder
T21945	Norepinephrine transporter	BFJ39T	(RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piperidine	Investigative	16102752	C15H22ClN	251.79	CC(C)C(C1CCCCN1)C2=CC=C(C=C2)Cl	Ki > 10000000 nM	Non binder
T21945	Norepinephrine transporter	BFZ45K	Sodium 2-methoxy-5-[(1S)-3-(methylamino)-1-(thiophen-2-yl)propoxy]naphthalen-1-yl sulfate	Investigative	44344091	C19H20NNaO6S2	445.5	CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=C2C=CC(=C3OS(=O)(=O)[O-])OC.[Na+]	Ki > 10000000 nM	Non binder
T21945	Norepinephrine transporter	BG1S6H	Ethyl (1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylate	Investigative	137653998	C21H20ClN5O4S	473.9	CCOC(=O)[C@@]12C[C@@H]1[C@H]([C@@H]([C@@H]2O)O)N3C=NC4=C(N=C(N=C43)C#CC5=CC=C(S5)Cl)NC	EC50 > 8400000 nM	Non binder
T21945	Norepinephrine transporter	BGI86B	Methyl 2-(4-(trifluoromethoxy)phenyl)cyclopent-1-enecarboxylate	Investigative	44429195	C14H13F3O3	286.25	COC(=O)C1=C(CCC1)C2=CC=C(C=C2)OC(F)(F)F	Ki = 2884000 nM	Non binder
T21945	Norepinephrine transporter	BKY43I	5-Hydroxy-6-methoxy Duloxetine	Investigative	29981679	C19H21NO3S	343.4	CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=C2C=CC(=C3O)OC	Ki = 920000 nM	Non binder
T21945	Norepinephrine transporter	BL7JV0	Methyl 2-phenylcyclohexanecarboxylate	Investigative	44429396	C14H18O2	218.29	COC(=O)[C@@H]1CCCC[C@@H]1C2=CC=CC=C2	Ki = 1360000 nM	Non binder
T21945	Norepinephrine transporter	BLYC86	Methyl 2-(3-chlorophenyl)cyclopent-1-enecarboxylate	Investigative	44429191	C13H13ClO2	236.69	COC(=O)C1=C(CCC1)C2=CC(=CC=C2)Cl	Ki = 285000 nM	Non binder
T21945	Norepinephrine transporter	BO3D5E	4-(Benzhydrylsulfinylmethyl)-2,6-dimethylpyrimidine	Investigative	137658186	C20H20N2OS	336.5	CC1=CC(=NC(=N1)C)CS(=O)C(C2=CC=CC=C2)C3=CC=CC=C3	IC50 = 767500 nM	Non binder
T21945	Norepinephrine transporter	BP0RB5	1-Methoxy-5-((S)-3-methylamino-1-thiophen-2-yl-propoxy)-naphthalen-2-ol	Investigative	44344218	C19H21NO3S	343.4	CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=C2C=CC(=C3OC)O	Ki = 235500 nM	Non binder
T21945	Norepinephrine transporter	BQX4B9	Methyl 2-(biphenyl-4-yl)cyclohexanecarboxylate	Investigative	44429392	C20H22O2	294.4	COC(=O)[C@@H]1CCCC[C@@H]1C2=CC=C(C=C2)C3=CC=CC=C3	Ki = 658000 nM	Non binder
T21945	Norepinephrine transporter	BR53YM	(2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-[5-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]naphthalen-2-yl]oxyoxane-2-carboxylic acid	Investigative	70685727	C24H27NO8S	489.5	CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=C2C=CC(=C3)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O	Ki = 5454000 nM	Non binder
T21945	Norepinephrine transporter	BS8XE2	(2-(3,4-Dichlorophenyl)cyclopent-1-enyl)(pyrrolidin-1-yl)methanone	Investigative	44443875	C16H17Cl2NO	310.2	C1CCN(C1)C(=O)C2=C(CCC2)C3=CC(=C(C=C3)Cl)Cl	Ki = 410000 nM	Non binder
T21945	Norepinephrine transporter	BV78RM	2-(3,4-Dichlorophenyl)-N-methoxy-N-methylcyclopent-1-enecarboxamide	Investigative	44443888	C14H15Cl2NO2	300.2	CN(C(=O)C1=C(CCC1)C2=CC(=C(C=C2)Cl)Cl)OC	Ki = 250000 nM	Non binder
T21945	Norepinephrine transporter	BVBS46	Methyl 2-(4-tert-butylphenyl)cyclohexanecarboxylate	Investigative	44429393	C18H26O2	274.4	CC(C)(C)C1=CC=C(C=C1)[C@H]2CCCC[C@H]2C(=O)OC	Ki = 675000 nM	Non binder
T21945	Norepinephrine transporter	BVJ7L3	Methyl 2-(4-methoxyphenyl)cyclopent-1-enecarboxylate	Investigative	44429193	C14H16O3	232.27	COC1=CC=C(C=C1)C2=C(CCC2)C(=O)OC	Ki = 550000 nM	Non binder
T21945	Norepinephrine transporter	BW4I1B	5-[(1S)-3-(Methylamino)-1-(thiophen-2-yl)propoxy]naphthalene-1,2-diol	Investigative	44344115	C18H19NO3S	329.4	CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=C2C=CC(=C3O)O	Ki = 554000 nM	Non binder
T21945	Norepinephrine transporter	BWK3E4	Methyl 2-(4-(trifluoromethyl)phenyl)cyclohexanecarboxylate	Investigative	44429399	C15H17F3O2	286.29	COC(=O)[C@@H]1CCCC[C@@H]1C2=CC=C(C=C2)C(F)(F)F	Ki = 439000 nM	Non binder
T21945	Norepinephrine transporter	BX5BZ6	1,2-Dichloro-4-(2-(prop-1-enyl)cyclohex-1-enyl)benzene	Investigative	44429227	C15H16Cl2	267.2	C/C=C/C1=C(CCCC1)C2=CC(=C(C=C2)Cl)Cl	Ki = 255000 nM	Non binder
T21945	Norepinephrine transporter	BX9E3U	2-(3,4-Dichlorophenyl)-N,N-diethylcyclopent-1-enecarboxamide	Investigative	44443877	C16H19Cl2NO	312.2	CCN(CC)C(=O)C1=C(CCC1)C2=CC(=C(C=C2)Cl)Cl	Ki = 210000 nM	Non binder
T21945	Norepinephrine transporter	BXMW81	Methyl 2-(4-(trifluoromethyl)phenyl)cyclohex-1-enecarboxylate	Investigative	44429210	C15H15F3O2	284.27	COC(=O)C1=C(CCCC1)C2=CC=C(C=C2)C(F)(F)F	Ki = 2020000 nM	Non binder
T21945	Norepinephrine transporter	D00NEE	Bip-tyr-thr-pro-lys-thr	Investigative	44413628	C46H62N8O12	919	C[C@H]([C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)O)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CC3=CC=C(C=C3)C4=CC=C(C=C4)C[C@@H](C(=O)O)N)N)O	IC50 > 1000000 nM	Non binder
T21945	Norepinephrine transporter	D0NC3P	(-)-cubebin	Investigative	117443	C20H20O6	356.4	C1[C@@H]([C@H]([C@H](O1)O)CC2=CC3=C(C=C2)OCO3)CC4=CC5=C(C=C4)OCO5	IC50 > 200000 nM	Non binder