TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T23172	Janus kinase 3	B20CVE	3-Morpholin-4-yl-1-phenanthren-3-ylpropan-1-one;hydrochloride	Investigative	24200928	C21H22ClNO2	355.9	C1COCCN1CCC(=O)C2=CC3=C(C=CC4=CC=CC=C43)C=C2.Cl	IC50 = 2000000000000000 nM	Non binder
T23172	Janus kinase 3	B2GS7B	ZM 39923 hydrochloride	Investigative	176406	C23H26ClNO	367.9	CC(C)N(CCC(=O)C1=CC2=CC=CC=C2C=C1)CC3=CC=CC=C3.Cl	IC50 = 12600000000000000 nM	Non binder
T23172	Janus kinase 3	B7ZQ2W	(E)-2-Methyl-5-morpholin-4-yl-1-phenylpent-1-en-3-one;hydrochloride	Investigative	5386794	C16H22ClNO2	295.8	C/C(=C\\C1=CC=CC=C1)/C(=O)CCN2CCOCC2.Cl	IC50 = 79400000000000 nM	Non binder
T23172	Janus kinase 3	B9E0YH	1-(2-Naphthalenyl)-2-propen-1-one	Investigative	3799	C13H10O	182.22	C=CC(=O)C1=CC2=CC=CC=C2C=C1	IC50 = 12600000000000000 nM	Non binder
T23172	Janus kinase 3	BA7Z0I	3-(Dimethylamino)-1-(naphthalen-2-yl)propan-1-one hydrochloride	Investigative	12345045	C15H18ClNO	263.76	CN(C)CCC(=O)C1=CC2=CC=CC=C2C=C1.Cl	IC50 = 1580000000000000 nM	Non binder
T23172	Janus kinase 3	BDRQ89	N-(6-(6,7-Dimethoxyquinolin-4-yloxy)-1-methyl-1H-indazol-3-yl)-3-(trifluoromethyl)benzamide	Investigative	11398307	C27H21F3N4O4	522.5	CN1C2=C(C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)C(=N1)NC(=O)C5=CC(=CC=C5)C(F)(F)F	IC50 = 25000000 nM	Non binder
T23172	Janus kinase 3	BF7M2E	3-(Azepan-1-yl)-1-naphthalen-2-ylpropan-1-one;hydrochloride	Investigative	45262601	C19H24ClNO	317.9	C1CCCN(CC1)CCC(=O)C2=CC3=CC=CC=C3C=C2.Cl	IC50 = 1260000000000000 nM	Non binder
T23172	Janus kinase 3	BH2GI7	1-(2-Aminoethyl)-2-(4-piperidinyl)-1H-benzoimidazole-5-carboxamide	Investigative	122192069	C15H21N5O	287.36	C1CNCCC1C2=NC3=C(N2CCN)C=CC(=C3)C(=O)N	IC50 = 232500 nM	Non binder
T23172	Janus kinase 3	BKW5L4	1-(6,7-Dimethoxynaphthalen-2-yl)-3-morpholin-4-ylpropan-1-one;hydrochloride	Investigative	45262575	C19H24ClNO4	365.8	COC1=C(C=C2C=C(C=CC2=C1)C(=O)CCN3CCOCC3)OC.Cl	IC50 = 5010000000000 nM	Non binder
T23172	Janus kinase 3	BMWN64	3-(Morpholin-4-yl)-1-(naphthalen-2-yl)propan-1-one hydrochloride	Investigative	2807049	C17H20ClNO2	305.8	C1COCCN1CCC(=O)C2=CC3=CC=CC=C3C=C2.Cl	IC50 = 501000000000000 nM	Non binder
T23172	Janus kinase 3	BQ9J3N	(E)-1-(2-Chlorophenyl)-5-morpholin-4-ylpent-1-en-3-one;hydrochloride	Investigative	49797208	C15H19Cl2NO2	316.2	C1COCCN1CCC(=O)/C=C/C2=CC=CC=C2Cl.Cl	IC50 = 79400000000000 nM	Non binder
T23172	Janus kinase 3	BS9F6G	1-(2-Naphthyl)-2-propen-1-ol	Investigative	10921194	C13H12O	184.23	C=CC(C1=CC2=CC=CC=C2C=C1)O	IC50 = 2000000000000 nM	Non binder
T23172	Janus kinase 3	BW3J0S	3-(Morpholin-4-yl)-1-(naphthalen-1-yl)propan-1-one hydrochloride	Investigative	45262629	C17H20ClNO2	305.8	C1COCCN1CCC(=O)C2=CC=CC3=CC=CC=C32.Cl	IC50 = 316000000000000 nM	Non binder
T23172	Janus kinase 3	BX68SH	1-(6-Methoxynaphthalen-2-yl)-3-morpholin-4-ylpropan-1-one;hydrochloride	Investigative	12273754	C18H22ClNO3	335.8	COC1=CC2=C(C=C1)C=C(C=C2)C(=O)CCN3CCOCC3.Cl	IC50 = 63100000000000 nM	Non binder