TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T24595	Acrosin	B0A1VF	Ethyl 3-[4-[(4-fluorobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate	Investigative	56682077	C19H16FN3O3	353.3	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)F	IC50 = 2400000 nM	Non binder
T24595	Acrosin	B0BXF3	Methyl N-[6-[[4-(trifluoromethyl)phenyl]methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70685601	C17H15F3N4O4S	428.4	COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)(=O)NCC3=CC=C(C=C3)C(F)(F)F	IC50 = 10700000 nM	Non binder
T24595	Acrosin	B0D5XN	3-(4-Bromophenyl)-N-[2-(2-hydroxyethoxy)ethyl]-1H-pyrazole-5-carboxamide	Investigative	71713487	C14H16BrN3O3	354.2	C1=CC(=CC=C1C2=NNC(=C2)C(=O)NCCOCCO)Br	IC50 = 10000000 nM	Non binder
T24595	Acrosin	B0Q9IZ	Ethyl 5-(4-benzamidophenyl)-1,2-oxazole-3-carboxylate	Investigative	60142777	C19H16N2O4	336.3	CCOC(=O)C1=NOC(=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3	IC50 = 460000 nM	Non binder
T24595	Acrosin	B0RZ4Y	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(3-methylphenoxy)acetamide	Investigative	57398037	C16H18N4O4S	362.4	CC1=CC(=CC=C1)OCC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 8920000 nM	Non binder
T24595	Acrosin	B19XAH	Methyl N-[6-[(4-fluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70691883	C16H15FN4O4S	378.4	COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)(=O)NCC3=CC=C(C=C3)F	IC50 = 2400000 nM	Non binder
T24595	Acrosin	B1CHR2	N-(2-Hydroxypropyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713191	C13H14N4O4	290.27	CC(CNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)[N+](=O)[O-])O	IC50 = 2950000 nM	Non binder
T24595	Acrosin	B2MC7G	Methyl 1-[2-[4-(diaminomethylideneamino)sulfonylanilino]-2-oxoethyl]piperidine-4-carboxylate	Investigative	57394480	C16H23N5O5S	397.5	COC(=O)C1CCN(CC1)CC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 9300000 nM	Non binder
T24595	Acrosin	B2UAF4	N-(2-Hydroxypropyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide	Investigative	71569744	C14H17N3O3	275.3	CC(CNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC)O	IC50 = 8920000 nM	Non binder
T24595	Acrosin	B30RGT	Ethyl 3-(4-acetamidophenyl)-1H-pyrazole-5-carboxylate	Investigative	56671784	C14H15N3O3	273.29	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C	IC50 = 23000000 nM	Non binder
T24595	Acrosin	B38ZWU	Ethyl 3-[4-[[4-(chloromethyl)benzoyl]amino]phenyl]-1H-pyrazole-5-carboxylate	Investigative	56665091	C20H18ClN3O3	383.8	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)CCl	IC50 = 3310000 nM	Non binder
T24595	Acrosin	B3IN4Z	N-(6-Bromo-1,3-benzothiazol-2-yl)-2-(dipentylamino)acetamide	Investigative	71569574	C19H28BrN3OS	426.4	CCCCCN(CCCCC)CC(=O)NC1=NC2=C(S1)C=C(C=C2)Br	IC50 = 540000 nM	Non binder
T24595	Acrosin	B3O2WG	2,4-Dichloro-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide	Investigative	57403193	C14H12Cl2N4O3S	387.2	C1=CC(=CC=C1NC(=O)C2=C(C=C(C=C2)Cl)Cl)S(=O)(=O)N=C(N)N	IC50 = 5630000 nM	Non binder
T24595	Acrosin	B3PT2D	Ethyl 1-[2-[4-(diaminomethylideneamino)sulfonylanilino]-2-oxoethyl]piperidine-4-carboxylate	Investigative	57390966	C17H25N5O5S	411.5	CCOC(=O)C1CCN(CC1)CC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 2990000 nM	Non binder
T24595	Acrosin	B3RTG9	Methyl N-[6-[(2-chlorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70683428	C16H15ClN4O4S	394.8	COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)(=O)NCC3=CC=CC=C3Cl	IC50 = 5750000 nM	Non binder
T24595	Acrosin	B3U4LV	4-(Chloromethyl)-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide	Investigative	57390964	C15H15ClN4O3S	366.8	C1=CC(=CC=C1CCl)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 3840000 nM	Non binder
T24595	Acrosin	B3XBU6	5-(2,4-Dichlorophenyl)isoxazole-3-carbaldehyde	Investigative	16728293	C10H5Cl2NO2	242.05	C1=CC(=C(C=C1Cl)Cl)C2=CC(=NO2)C=O	IC50 = 390000 nM	Non binder
T24595	Acrosin	B3ZKN8	N-(2-Hydroxypropyl)-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713347	C13H14N4O4	290.27	CC(CNC(=O)C1=CC(=NN1)C2=CC(=CC=C2)[N+](=O)[O-])O	IC50 = 1830000 nM	Non binder
T24595	Acrosin	B4C1SO	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-4-fluorobenzamide	Investigative	57392743	C14H13FN4O3S	336.34	C1=CC(=CC=C1C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N)F	IC50 = 7110000 nM	Non binder
T24595	Acrosin	B4D0HG	1-(2-Hydroxyethyl)-3-[6-[(2-methoxyphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]urea	Investigative	71569568	C18H21N5O5S	419.5	COC1=CC=CC=C1CNS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)NCCO	IC50 = 6040000 nM	Non binder
T24595	Acrosin	B4GM0A	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(4-methoxyphenoxy)acetamide	Investigative	57399697	C16H18N4O5S	378.4	COC1=CC=C(C=C1)OCC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 9840000 nM	Non binder
T24595	Acrosin	B4VS7R	Ethyl 3-[4-(pentanoylamino)phenyl]-1H-pyrazole-5-carboxylate	Investigative	56668303	C17H21N3O3	315.37	CCCCC(=O)NC1=CC=C(C=C1)C2=NNC(=C2)C(=O)OCC	IC50 = 72000000 nM	Non binder
T24595	Acrosin	B4YVL5	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2,6-difluorobenzamide	Investigative	57399696	C14H12F2N4O3S	354.33	C1=CC(=C(C(=C1)F)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N)F	IC50 = 7180000 nM	Non binder
T24595	Acrosin	B54KBY	1-[6-(Benzylsulfamoyl)-1H-benzimidazol-2-yl]-3-(2-hydroxyethyl)urea	Investigative	71569570	C17H19N5O4S	389.4	C1=CC=C(C=C1)CNS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)NCCO	IC50 = 280000 nM	Non binder
T24595	Acrosin	B5BI9D	N-[4-(Diaminomethylideneamino)sulfonylphenyl]propanamide	Investigative	57398035	C10H14N4O3S	270.31	CCC(=O)NC1=CC=C(C=C1)S(=O)(=O)N=C(N)N	IC50 = 9000000 nM	Non binder
T24595	Acrosin	B5JKS2	Ethyl 3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate	Investigative	56678768	C19H15Cl2N3O3	404.2	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C3=C(C=CC=C3Cl)Cl	IC50 = 4800000 nM	Non binder
T24595	Acrosin	B5P0NG	N,N-Bis(2-hydroxyethyl)-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713345	C14H16N4O5	320.3	C1=CC(=CC(=C1)[N+](=O)[O-])C2=NNC(=C2)C(=O)N(CCO)CCO	IC50 = 2400000 nM	Non binder
T24595	Acrosin	B5RSN1	N-[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713343	C14H16N4O6	336.3	C1=CC(=CC=C1C2=NNC(=C2)C(=O)NC(CO)(CO)CO)[N+](=O)[O-]	IC50 = 5220000 nM	Non binder
T24595	Acrosin	B5SAQ2	Methyl N-[6-[(4-methylphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70687753	C17H18N4O4S	374.4	CC1=CC=C(C=C1)CNS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)OC	IC50 = 3180000 nM	Non binder
T24595	Acrosin	B5UQ0E	N-(2-Hydroxyethyl)-N-methyl-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713193	C13H14N4O4	290.27	CN(CCO)C(=O)C1=CC(=NN1)C2=CC=C(C=C2)[N+](=O)[O-]	IC50 = 2000000 nM	Non binder
T24595	Acrosin	B5V3OG	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(2-methylpiperidin-1-yl)acetamide	Investigative	57392745	C15H23N5O3S	353.4	CC1CCCCN1CC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 9900000 nM	Non binder
T24595	Acrosin	B61CVE	N-(2-Hydroxyethyl)-3-(4-methoxyphenyl)-N-methyl-1H-pyrazole-5-carboxamide	Investigative	71569741	C14H17N3O3	275.3	CN(CCO)C(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC	IC50 = 410000 nM	Non binder
T24595	Acrosin	B69CIG	N-[2-(2-Hydroxyethoxy)ethyl]-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713342	C14H16N4O5	320.3	C1=CC(=CC=C1C2=NNC(=C2)C(=O)NCCOCCO)[N+](=O)[O-]	IC50 = 2070000 nM	Non binder
T24595	Acrosin	B6B1NV	4-[4-(5-Ethoxycarbonyl-1H-pyrazol-3-yl)anilino]-4-oxobutanoic acid	Investigative	56657917	C16H17N3O5	331.32	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)CCC(=O)O	IC50 = 9250000 nM	Non binder
T24595	Acrosin	B6DZ2N	3,4-Dichloro-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide	Investigative	57394476	C14H12Cl2N4O3S	387.2	C1=CC(=CC=C1NC(=O)C2=CC(=C(C=C2)Cl)Cl)S(=O)(=O)N=C(N)N	IC50 = 3800000 nM	Non binder
T24595	Acrosin	B6E5HV	3-(4-Bromophenyl)-N,N-bis(2-hydroxyethyl)-1H-pyrazole-5-carboxamide	Investigative	71713483	C14H16BrN3O3	354.2	C1=CC(=CC=C1C2=NNC(=C2)C(=O)N(CCO)CCO)Br	IC50 = 1520000 nM	Non binder
T24595	Acrosin	B6IHQ1	Methyl N-[6-[(2,4-dichlorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70693922	C16H14Cl2N4O4S	429.3	COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)(=O)NCC3=C(C=C(C=C3)Cl)Cl	IC50 = 1270000 nM	Non binder
T24595	Acrosin	B6IUF0	Propan-2-yl 1-[2-[4-(diaminomethylideneamino)sulfonylanilino]-2-oxoethyl]piperidine-4-carboxylate	Investigative	57401455	C18H27N5O5S	425.5	CC(C)OC(=O)C1CCN(CC1)CC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 2350000 nM	Non binder
T24595	Acrosin	B6S7PR	Ethyl 1-(2,4-dichlorobenzoyl)indazole-3-carboxylate	Investigative	71569745	C17H12Cl2N2O3	363.2	CCOC(=O)C1=NN(C2=CC=CC=C21)C(=O)C3=C(C=C(C=C3)Cl)Cl	IC50 = 3240000 nM	Non binder
T24595	Acrosin	B6Y1VH	Methyl N-[6-[(2,5-dimethylphenyl)sulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70689735	C17H18N4O4S	374.4	CC1=CC(=C(C=C1)C)NS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)OC	IC50 = 8860000 nM	Non binder
T24595	Acrosin	B75QVP	Methyl N-[6-[(3,4-difluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70685603	C16H14F2N4O4S	396.4	COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)(=O)NCC3=CC(=C(C=C3)F)F	IC50 = 1590000 nM	Non binder
T24595	Acrosin	B78LUF	Methyl N-[6-[benzyl(methyl)sulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70696118	C17H18N4O4S	374.4	CN(CC1=CC=CC=C1)S(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)OC	IC50 = 1250000 nM	Non binder
T24595	Acrosin	B7BSK6	3-(4-Bromophenyl)-N-(2-hydroxyethyl)-1H-pyrazole-5-carboxamide	Investigative	71713482	C12H12BrN3O2	310.15	C1=CC(=CC=C1C2=NNC(=C2)C(=O)NCCO)Br	IC50 = 530000 nM	Non binder
T24595	Acrosin	B7IZ1N	N,N-Bis(2-hydroxyethyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide	Investigative	71569742	C15H19N3O4	305.33	COC1=CC=C(C=C1)C2=NNC(=C2)C(=O)N(CCO)CCO	IC50 = 5730000 nM	Non binder
T24595	Acrosin	B7LN6K	2-[Bis(3-methylbutyl)amino]-N-(6-bromo-1,3-benzothiazol-2-yl)acetamide	Investigative	71569573	C19H28BrN3OS	426.4	CC(C)CCN(CCC(C)C)CC(=O)NC1=NC2=C(S1)C=C(C=C2)Br	IC50 = 1090000 nM	Non binder
T24595	Acrosin	B7TL6R	1-[6-[(3,5-Difluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]-3-(2-hydroxyethyl)urea	Investigative	71569410	C17H17F2N5O4S	425.4	C1=CC2=C(C=C1S(=O)(=O)NCC3=CC(=CC(=C3)F)F)NC(=N2)NC(=O)NCCO	IC50 = 340000 nM	Non binder
T24595	Acrosin	B7WLT4	Tosyl-L-lysine chloromethyl ketone	Investigative	73094	C14H21ClN2O3S	332.8	CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl	IC50 = 142600000 nM	Non binder
T24595	Acrosin	B8O7ZB	2,6-Dichloro-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide	Investigative	57396240	C14H12Cl2N4O3S	387.2	C1=CC(=C(C(=C1)Cl)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N)Cl	IC50 = 5960000 nM	Non binder
T24595	Acrosin	B8P2TW	N,N-Bis(2-hydroxypropyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713192	C16H20N4O5	348.35	CC(CN(CC(C)O)C(=O)C1=CC(=NN1)C2=CC=C(C=C2)[N+](=O)[O-])O	IC50 = 1210000 nM	Non binder
T24595	Acrosin	B8Z6QJ	5-[4-(5-Ethoxycarbonyl-1H-pyrazol-3-yl)anilino]-5-oxopentanoic acid	Investigative	56671785	C17H19N3O5	345.3	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)CCCC(=O)O	IC50 = 17400000 nM	Non binder
T24595	Acrosin	BA0OJ4	N-(2-Hydroxyethyl)-N-methyl-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713348	C13H14N4O4	290.27	CN(CCO)C(=O)C1=CC(=NN1)C2=CC(=CC=C2)[N+](=O)[O-]	IC50 = 790000 nM	Non binder
T24595	Acrosin	BA6U8J	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-phenoxyacetamide	Investigative	12241396	C15H16N4O4S	348.4	C1=CC=C(C=C1)OCC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 2300000 nM	Non binder
T24595	Acrosin	BAI2Y4	N-(1-Hydroxy-2-methylpropan-2-yl)-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713194	C14H16N4O4	304.3	CC(C)(CO)NC(=O)C1=CC(=NN1)C2=CC=C(C=C2)[N+](=O)[O-]	IC50 = 1875000 nM	Non binder
T24595	Acrosin	BAT97J	Ethyl 3-[4-(butanoylamino)phenyl]-1H-pyrazole-5-carboxylate	Investigative	56657915	C16H19N3O3	301.34	CCCC(=O)NC1=CC=C(C=C1)C2=NNC(=C2)C(=O)OCC	IC50 = 17000000 nM	Non binder
T24595	Acrosin	BB1HV0	Methyl N-[6-(propan-2-ylsulfamoyl)-1H-benzimidazol-2-yl]carbamate	Investigative	70687755	C12H16N4O4S	312.35	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)N=C(N2)NC(=O)OC	IC50 = 470000 nM	Non binder
T24595	Acrosin	BB24PN	Tosyllysine chloromethyl ketone	Investigative	4427	C14H21ClN2O3S	332.8	CC1=CC=C(C=C1)S(=O)(=O)NC(CCCCN)C(=O)CCl	IC50 = 142600000 nM	Non binder
T24595	Acrosin	BB43CN	Methyl N-[6-[(3-methylphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70693994	C17H18N4O4S	374.4	CC1=CC(=CC=C1)CNS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)OC	IC50 = 5060000 nM	Non binder
T24595	Acrosin	BBG36A	N-(1-Hydroxypropan-2-yl)-3-phenyl-1H-pyrazole-5-carboxamide	Investigative	43418690	C13H15N3O2	245.28	CC(CO)NC(=O)C1=CC(=NN1)C2=CC=CC=C2	IC50 = 3000000 nM	Non binder
T24595	Acrosin	BBTA16	Methyl N-[6-[(3,4-dimethoxyphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70687754	C18H20N4O6S	420.4	COC1=C(C=C(C=C1)CNS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)OC)OC	IC50 = 11500000 nM	Non binder
T24595	Acrosin	BC19BL	N-(6-Bromo-1,3-benzothiazol-2-yl)-2-(dibutylamino)acetamide	Investigative	71717981	C17H24BrN3OS	398.4	CCCCN(CCCC)CC(=O)NC1=NC2=C(S1)C=C(C=C2)Br	IC50 = 2780000 nM	Non binder
T24595	Acrosin	BD91IL	Methyl N-[6-(benzylsulfamoyl)-1H-benzimidazol-2-yl]carbamate	Investigative	70693995	C16H16N4O4S	360.4	COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)(=O)NCC3=CC=CC=C3	IC50 = 1030000 nM	Non binder
T24595	Acrosin	BD9TS8	Ethyl 3-[4-[(2,2,2-trifluoroacetyl)amino]phenyl]-1H-pyrazole-5-carboxylate	Investigative	56668304	C14H12F3N3O3	327.26	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C(F)(F)F	IC50 = 7900000 nM	Non binder
T24595	Acrosin	BDK53W	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2,4,6-trimethylbenzamide	Investigative	57401454	C17H20N4O3S	360.4	CC1=CC(=C(C(=C1)C)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N)C	IC50 = 2450000 nM	Non binder
T24595	Acrosin	BE2C7O	Methyl N-[6-[(2-methoxyphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70685604	C17H18N4O5S	390.4	COC1=CC=CC=C1CNS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)OC	IC50 = 8420000 nM	Non binder
T24595	Acrosin	BE5NP8	N-(2-Hydroxyethyl)-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713344	C12H12N4O4	276.25	C1=CC(=CC(=C1)[N+](=O)[O-])C2=NNC(=C2)C(=O)NCCO	IC50 = 760000 nM	Non binder
T24595	Acrosin	BEC13M	Propyl 1-[2-[4-(diaminomethylideneamino)sulfonylanilino]-2-oxoethyl]piperidine-4-carboxylate	Investigative	57394481	C18H27N5O5S	425.5	CCCOC(=O)C1CCN(CC1)CC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 3310000 nM	Non binder
T24595	Acrosin	BEO24D	Ethyl 3-[4-[(2,6-difluorobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate	Investigative	56665089	C19H15F2N3O3	371.3	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C3=C(C=CC=C3F)F	IC50 = 3980000 nM	Non binder
T24595	Acrosin	BEP5S2	Methyl N-[6-[(3,4-dichlorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70691885	C16H14Cl2N4O4S	429.3	COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)(=O)NCC3=CC(=C(C=C3)Cl)Cl	IC50 = 4020000 nM	Non binder
T24595	Acrosin	BF34QE	1-(2-Hydroxyethyl)-3-[6-[(3-methylphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]urea	Investigative	71569569	C18H21N5O4S	403.5	CC1=CC(=CC=C1)CNS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)NCCO	IC50 = 5450000 nM	Non binder
T24595	Acrosin	BF71SU	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-3,5-dinitrobenzamide	Investigative	403858	C14H12N6O7S	408.35	C1=CC(=CC=C1NC(=O)C2=CC(=CC(=C2)[N+](=O)[O-])[N+](=O)[O-])S(=O)(=O)N=C(N)N	IC50 = 2500000 nM	Non binder
T24595	Acrosin	BFE50A	N-[2-(2-Hydroxyethoxy)ethyl]-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713349	C14H16N4O5	320.3	C1=CC(=CC(=C1)[N+](=O)[O-])C2=NNC(=C2)C(=O)NCCOCCO	IC50 = 9100000 nM	Non binder
T24595	Acrosin	BFQ0L5	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(4-methylphenoxy)acetamide	Investigative	57394482	C16H18N4O4S	362.4	CC1=CC=C(C=C1)OCC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 8980000 nM	Non binder
T24595	Acrosin	BFW27C	Methyl N-[6-[(4-bromophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70693921	C16H15BrN4O4S	439.3	COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)(=O)NCC3=CC=C(C=C3)Br	IC50 = 1640000 nM	Non binder
T24595	Acrosin	BG05IK	3-(4-Bromophenyl)-N-(2-hydroxypropyl)-1H-pyrazole-5-carboxamide	Investigative	71713485	C13H14BrN3O2	324.17	CC(CNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)Br)O	IC50 = 330000 nM	Non binder
T24595	Acrosin	BG10US	Ethyl 3-[4-[(2-phenylacetyl)amino]phenyl]-1H-pyrazole-5-carboxylate	Investigative	56672042	C20H19N3O3	349.4	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)CC3=CC=CC=C3	IC50 = 470000 nM	Non binder
T24595	Acrosin	BGFK07	Methyl N-[6-(hexylsulfamoyl)-1H-benzimidazol-2-yl]carbamate	Investigative	70687756	C15H22N4O4S	354.4	CCCCCCNS(=O)(=O)C1=CC2=C(C=C1)N=C(N2)NC(=O)OC	IC50 = 1800000 nM	Non binder
T24595	Acrosin	BH03DP	Methyl N-[6-[(4-methoxyphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70691886	C17H18N4O5S	390.4	COC1=CC=C(C=C1)CNS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)OC	IC50 = 3290000 nM	Non binder
T24595	Acrosin	BHI1F5	Ethyl 5-[4-[(4-chlorobenzoyl)amino]phenyl]-1,2-oxazole-3-carboxylate	Investigative	60142778	C19H15ClN2O4	370.8	CCOC(=O)C1=NOC(=C1)C2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)Cl	IC50 = 380000 nM	Non binder
T24595	Acrosin	BHJD46	N-(2-Hydroxyethyl)-3-phenyl-1H-pyrazole-5-carboxamide	Investigative	43392945	C12H13N3O2	231.25	C1=CC=C(C=C1)C2=NNC(=C2)C(=O)NCCO	IC50 = 2800000 nM	Non binder
T24595	Acrosin	BI9Q3F	N-(3-Hydroxypropyl)-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713346	C13H14N4O4	290.27	C1=CC(=CC(=C1)[N+](=O)[O-])C2=NNC(=C2)C(=O)NCCCO	IC50 = 780000 nM	Non binder
T24595	Acrosin	BIAU87	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-3-(trifluoromethyl)benzamide	Investigative	57392744	C15H13F3N4O3S	386.4	C1=CC(=CC(=C1)C(F)(F)F)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 7050000 nM	Non binder
T24595	Acrosin	BIN01E	Methyl N-[6-(butylsulfamoyl)-1H-benzimidazol-2-yl]carbamate	Investigative	70691944	C13H18N4O4S	326.37	CCCCNS(=O)(=O)C1=CC2=C(C=C1)N=C(N2)NC(=O)OC	IC50 = 1770000 nM	Non binder
T24595	Acrosin	BJ8E2T	1-[6-[(3,5-Dichlorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]-3-(2-hydroxyethyl)urea	Investigative	71569409	C17H17Cl2N5O4S	458.3	C1=CC2=C(C=C1S(=O)(=O)NCC3=CC(=CC(=C3)Cl)Cl)NC(=N2)NC(=O)NCCO	IC50 = 2450000 nM	Non binder
T24595	Acrosin	BJO42Z	N-[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]-3-phenyl-1H-pyrazole-5-carboxamide	Investigative	71713627	C14H17N3O4	291.3	C1=CC=C(C=C1)C2=NNC(=C2)C(=O)NC(CO)(CO)CO	IC50 = 940000 nM	Non binder
T24595	Acrosin	BK0J5X	1-(2-Hydroxyethyl)-3-[6-[(3-methoxyphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]urea	Investigative	71569408	C18H21N5O5S	419.5	COC1=CC=CC(=C1)CNS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)NCCO	IC50 = 7320000 nM	Non binder
T24595	Acrosin	BK49CS	N-[4-(Diaminomethylideneamino)sulfonylphenyl]butanamide	Investigative	57390965	C11H16N4O3S	284.34	CCCC(=O)NC1=CC=C(C=C1)S(=O)(=O)N=C(N)N	IC50 = 9580000 nM	Non binder
T24595	Acrosin	BK5M2F	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-piperidin-1-ylacetamide	Investigative	57403194	C14H21N5O3S	339.42	C1CCN(CC1)CC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 7410000 nM	Non binder
T24595	Acrosin	BK7CZ5	2-(4-Chlorophenoxy)-N-[4-(diaminomethylideneamino)sulfonylphenyl]acetamide	Investigative	57394483	C15H15ClN4O4S	382.8	C1=CC(=CC=C1NC(=O)COC2=CC=C(C=C2)Cl)S(=O)(=O)N=C(N)N	IC50 = 9350000 nM	Non binder
T24595	Acrosin	BKCJ34	Ethyl 3-[4-(2-phenylbutanoylamino)phenyl]-1H-pyrazole-5-carboxylate	Investigative	56682079	C22H23N3O3	377.4	CCC(C1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)C3=NNC(=C3)C(=O)OCC	IC50 = 3300000 nM	Non binder
T24595	Acrosin	BKD92M	2-Chloro-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide	Investigative	57398034	C14H13ClN4O3S	352.8	C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N)Cl	IC50 = 6300000 nM	Non binder
T24595	Acrosin	BL5U9F	Ethyl 3-[4-[(2-bromobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate	Investigative	56665090	C19H16BrN3O3	414.3	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3Br	IC50 = 2400000 nM	Non binder
T24595	Acrosin	BLUR27	Methyl N-[6-[(2-fluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70689736	C16H15FN4O4S	378.4	COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)(=O)NCC3=CC=CC=C3F	IC50 = 310000 nM	Non binder
T24595	Acrosin	BLYC30	1-(2,4-Dichlorobenzoyl)-N-methylindazole-3-carboxamide	Investigative	71569746	C16H11Cl2N3O2	348.2	CNC(=O)C1=NN(C2=CC=CC=C21)C(=O)C3=C(C=C(C=C3)Cl)Cl	IC50 = 3780000 nM	Non binder
T24595	Acrosin	BM3H8X	Ethyl 5-[4-[(3,4-dichlorobenzoyl)amino]phenyl]-1,2-oxazole-3-carboxylate	Investigative	90644232	C19H14Cl2N2O4	405.2	CCOC(=O)C1=NOC(=C1)C2=CC=C(C=C2)NC(=O)C3=CC(=C(C=C3)Cl)Cl	IC50 = 240000 nM	Non binder
T24595	Acrosin	BMCJ70	N-(3-Hydroxypropyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713190	C13H14N4O4	290.27	C1=CC(=CC=C1C2=NNC(=C2)C(=O)NCCCO)[N+](=O)[O-]	IC50 = 3070000 nM	Non binder
T24595	Acrosin	BN3S0P	Ethyl 3-(4-benzamidophenyl)-1H-pyrazole-5-carboxylate	Investigative	56664885	C19H17N3O3	335.4	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3	IC50 = 8000000 nM	Non binder
T24595	Acrosin	BNRH36	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(2-methylphenoxy)acetamide	Investigative	57396242	C16H18N4O4S	362.4	CC1=CC=CC=C1OCC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 9300000 nM	Non binder
T24595	Acrosin	BO1IP6	Ethyl 3-[4-[(4-methoxybenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate	Investigative	56672041	C20H19N3O4	365.4	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)OC	IC50 = 800000 nM	Non binder
T24595	Acrosin	BO4W7E	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-4-methylbenzamide	Investigative	5172643	C15H16N4O3S	332.4	CC1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 2060000 nM	Non binder
T24595	Acrosin	BO9K0J	N-(3-Hydroxypropyl)-3-phenyl-1H-pyrazole-5-carboxamide	Investigative	43417711	C13H15N3O2	245.28	C1=CC=C(C=C1)C2=NNC(=C2)C(=O)NCCCO	IC50 = 540000 nM	Non binder
T24595	Acrosin	BP57BZ	3-(4-Bromophenyl)-N-(1-hydroxypropan-2-yl)-1H-pyrazole-5-carboxamide	Investigative	71713486	C13H14BrN3O2	324.17	CC(CO)NC(=O)C1=CC(=NN1)C2=CC=C(C=C2)Br	IC50 = 880000 nM	Non binder
T24595	Acrosin	BPGU54	1-[6-(Hexylsulfamoyl)-1H-benzimidazol-2-yl]-3-(2-hydroxyethyl)urea	Investigative	71569572	C16H25N5O4S	383.5	CCCCCCNS(=O)(=O)C1=CC2=C(C=C1)N=C(N2)NC(=O)NCCO	IC50 = 1620000 nM	Non binder
T24595	Acrosin	BPH08B	Butyl 1-[2-[4-(diaminomethylideneamino)sulfonylanilino]-2-oxoethyl]piperidine-4-carboxylate	Investigative	57398036	C19H29N5O5S	439.5	CCCCOC(=O)C1CCN(CC1)CC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 9500000 nM	Non binder
T24595	Acrosin	BPV6W0	Methyl N-[6-[(3-fluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70693996	C16H15FN4O4S	378.4	COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)(=O)NCC3=CC(=CC=C3)F	IC50 = 1810000 nM	Non binder
T24595	Acrosin	BQ7H4Y	3-(4-Bromophenyl)-N-(3-hydroxypropyl)-1H-pyrazole-5-carboxamide	Investigative	71713484	C13H14BrN3O2	324.17	C1=CC(=CC=C1C2=NNC(=C2)C(=O)NCCCO)Br	IC50 = 380000 nM	Non binder
T24595	Acrosin	BQBE37	2-Bromo-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide	Investigative	57394477	C14H13BrN4O3S	397.25	C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N)Br	IC50 = 7630000 nM	Non binder
T24595	Acrosin	BS26GE	Ethyl 3-[4-[(2,4-dichlorobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate	Investigative	53484116	C19H15Cl2N3O3	404.2	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C3=C(C=C(C=C3)Cl)Cl	IC50 = 440000 nM	Non binder
T24595	Acrosin	BS86HR	Methyl N-[6-[(2,4-difluorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70685602	C16H14F2N4O4S	396.4	COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)(=O)NCC3=C(C=C(C=C3)F)F	IC50 = 1550000 nM	Non binder
T24595	Acrosin	BSGL64	Methyl N-[6-[(4-chlorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70691884	C16H15ClN4O4S	394.8	COC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)(=O)NCC3=CC=C(C=C3)Cl	IC50 = 7520000 nM	Non binder
T24595	Acrosin	BU12EB	N-[4-(Diaminomethylideneamino)sulfonylphenyl]pentanamide	Investigative	57394479	C12H18N4O3S	298.36	CCCCC(=O)NC1=CC=C(C=C1)S(=O)(=O)N=C(N)N	IC50 = 1580000 nM	Non binder
T24595	Acrosin	BUZ9X4	N,N-Bis(2-hydroxyethyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713189	C14H16N4O5	320.3	C1=CC(=CC=C1C2=NNC(=C2)C(=O)N(CCO)CCO)[N+](=O)[O-]	IC50 = 5600000 nM	Non binder
T24595	Acrosin	BV1LB9	N-(2-Hydroxyethyl)-3-(4-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713188	C12H12N4O4	276.25	C1=CC(=CC=C1C2=NNC(=C2)C(=O)NCCO)[N+](=O)[O-]	IC50 = 2700000 nM	Non binder
T24595	Acrosin	BV1M2N	N-(3-Hydroxypropyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide	Investigative	71569743	C14H17N3O3	275.3	COC1=CC=C(C=C1)C2=NNC(=C2)C(=O)NCCCO	IC50 = 1430000 nM	Non binder
T24595	Acrosin	BV6A8N	3-Methylbutyl 1-[2-[4-(diaminomethylideneamino)sulfonylanilino]-2-oxoethyl]piperidine-4-carboxylate	Investigative	57396241	C20H31N5O5S	453.6	CC(C)CCOC(=O)C1CCN(CC1)CC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 2510000 nM	Non binder
T24595	Acrosin	BV6Y8Z	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(4-methylpiperidin-1-yl)acetamide	Investigative	57392746	C15H23N5O3S	353.4	CC1CCN(CC1)CC(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 4980000 nM	Non binder
T24595	Acrosin	BV7E1Q	3-Chloro-N-[4-(diaminomethylideneamino)sulfonylphenyl]benzamide	Investigative	57399695	C14H13ClN4O3S	352.8	C1=CC(=CC(=C1)Cl)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 7000000 nM	Non binder
T24595	Acrosin	BVM07H	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-4-methoxybenzamide	Investigative	57390307	C15H16N4O4S	348.4	COC1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 2210000 nM	Non binder
T24595	Acrosin	BW2OY0	Ethyl 3-[4-[(4-methylbenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate	Investigative	56675418	C20H19N3O3	349.4	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)C	IC50 = 34600000 nM	Non binder
T24595	Acrosin	BW3Q2A	1-[6-[(2-Chlorophenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]-3-(2-hydroxyethyl)urea	Investigative	71569571	C17H18ClN5O4S	423.9	C1=CC=C(C(=C1)CNS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)NCCO)Cl	IC50 = 1060000 nM	Non binder
T24595	Acrosin	BW4Z7X	Methyl N-[6-[(3-methoxyphenyl)methylsulfamoyl]-1H-benzimidazol-2-yl]carbamate	Investigative	70689804	C17H18N4O5S	390.4	COC1=CC=CC(=C1)CNS(=O)(=O)C2=CC3=C(C=C2)N=C(N3)NC(=O)OC	IC50 = 7500000 nM	Non binder
T24595	Acrosin	BX3DB1	Ethyl 3-[4-[(4-chlorobenzoyl)amino]phenyl]-1H-pyrazole-5-carboxylate	Investigative	56682078	C19H16ClN3O3	369.8	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)Cl	IC50 = 3310000 nM	Non binder
T24595	Acrosin	BXF81I	Ethyl 3-[4-(3-chloropropanoylamino)phenyl]-1H-pyrazole-5-carboxylate	Investigative	56657916	C15H16ClN3O3	321.76	CCOC(=O)C1=CC(=NN1)C2=CC=C(C=C2)NC(=O)CCCl	IC50 = 5760000 nM	Non binder
T24595	Acrosin	BY9ML1	N,N-Bis(2-hydroxyethyl)-3-phenyl-1H-pyrazole-5-carboxamide	Investigative	61236018	C14H17N3O3	275.3	C1=CC=C(C=C1)C2=NNC(=C2)C(=O)N(CCO)CCO	IC50 = 1700000 nM	Non binder
T24595	Acrosin	BYB64N	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-2-(4-nitrophenoxy)acetamide	Investigative	57401456	C15H15N5O6S	393.4	C1=CC(=CC=C1NC(=O)COC2=CC=C(C=C2)[N+](=O)[O-])S(=O)(=O)N=C(N)N	IC50 = 4200000 nM	Non binder
T24595	Acrosin	BZ2SD8	N-[2-(2-Hydroxyethoxy)ethyl]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide	Investigative	71713187	C15H19N3O4	305.33	COC1=CC=C(C=C1)C2=NNC(=C2)C(=O)NCCOCCO	IC50 = 6020000 nM	Non binder
T24595	Acrosin	BZ7FL0	N-[4-(Diaminomethylideneamino)sulfonylphenyl]-4-ethylbenzamide	Investigative	56930433	C16H18N4O3S	346.4	CCC1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)N=C(N)N	IC50 = 210000 nM	Non binder
T24595	Acrosin	BZ86CY	N-(6-Bromo-1,3-benzothiazol-2-yl)-2-(4-pentylpiperazin-1-yl)acetamide	Investigative	71569740	C18H25BrN4OS	425.4	CCCCCN1CCN(CC1)CC(=O)NC2=NC3=C(S2)C=C(C=C3)Br	IC50 = 5080000 nM	Non binder
T24595	Acrosin	BZ93MA	N-[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]-3-(3-nitrophenyl)-1H-pyrazole-5-carboxamide	Investigative	71713481	C14H16N4O6	336.3	C1=CC(=CC(=C1)[N+](=O)[O-])C2=NNC(=C2)C(=O)NC(CO)(CO)CO	IC50 = 760000 nM	Non binder
T24595	Acrosin	BZI73T	Ethyl 3-[4-(propanoylamino)phenyl]-1H-pyrazole-5-carboxylate	Investigative	56675194	C15H17N3O3	287.31	CCC(=O)NC1=CC=C(C=C1)C2=NNC(=C2)C(=O)OCC	IC50 = 14000000 nM	Non binder