TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T28887	Histone deacetylase 8	B0PL2O	Chembl4285950	Investigative	145990209	C28H31BN2O6S	534.4	B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)CONC(=O)/C=C/C3=CC(=CC=C3)S(=O)(=O)NC4=CC=CC=C4	EC50 = 341000 nM	Non binder
T28887	Histone deacetylase 8	B0SQP1	Methyl (2S)-2-(methanesulfonamido)-3-[4-(2-phenylethoxy)phenyl]propanoate	Investigative	71461879	C19H23NO5S	377.5	COC(=O)[C@H](CC1=CC=C(C=C1)OCCC2=CC=CC=C2)NS(=O)(=O)C	IC50 > 1000000 nM	Non binder
T28887	Histone deacetylase 8	B5ST1I	Methyl (2S)-2-benzamido-3-(4-phenylmethoxyphenyl)propanoate	Investigative	71452970	C24H23NO4	389.4	COC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC=CC=C2)NC(=O)C3=CC=CC=C3	IC50 > 1000000 nM	Non binder
T28887	Histone deacetylase 8	B69KTC	Methyl (2S)-2-[(4-methylphenyl)sulfonylamino]-3-[4-(2-phenylethoxy)phenyl]propanoate	Investigative	71461880	C25H27NO5S	453.6	CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CC=C(C=C2)OCCC3=CC=CC=C3)C(=O)OC	IC50 = 961800 nM	Non binder
T28887	Histone deacetylase 8	B72FHC	(2S)-2-[(4-Methylbenzoyl)amino]-3-[4-(2-phenylethoxy)phenyl]propanoic acid	Investigative	71460169	C25H25NO4	403.5	CC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OCCC3=CC=CC=C3)C(=O)O	IC50 = 385600 nM	Non binder
T28887	Histone deacetylase 8	B7A8PX	Methyl (2S)-2-acetamido-3-[4-(2-phenylethoxy)phenyl]propanoate	Investigative	71451145	C20H23NO4	341.4	CC(=O)N[C@@H](CC1=CC=C(C=C1)OCCC2=CC=CC=C2)C(=O)OC	IC50 = 825100 nM	Non binder
T28887	Histone deacetylase 8	B8EC0S	(2S)-2-[(4-Methylbenzoyl)amino]-3-(4-phenylmethoxyphenyl)propanoic acid	Investigative	71452973	C24H23NO4	389.4	CC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OCC3=CC=CC=C3)C(=O)O	IC50 > 1000000 nM	Non binder
T28887	Histone deacetylase 8	BA87EI	Methyl (2S)-2-benzamido-3-[4-(2-phenylethoxy)phenyl]propanoate	Investigative	71458326	C25H25NO4	403.5	COC(=O)[C@H](CC1=CC=C(C=C1)OCCC2=CC=CC=C2)NC(=O)C3=CC=CC=C3	IC50 > 1000000 nM	Non binder
T28887	Histone deacetylase 8	BBY20W	(2S)-2-[(4-Methylphenyl)sulfonylamino]-3-[4-(2-phenylethoxy)phenyl]propanoic acid	Investigative	71460171	C24H25NO5S	439.5	CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CC=C(C=C2)OCCC3=CC=CC=C3)C(=O)O	IC50 > 1000000 nM	Non binder
T28887	Histone deacetylase 8	BDP43W	N-Tosyl-O-benzyl-L-tyrosine	Investigative	10906013	C23H23NO5S	425.5	CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CC=C(C=C2)OCC3=CC=CC=C3)C(=O)O	IC50 = 504700 nM	Non binder
T28887	Histone deacetylase 8	BDY8G1	Methyl (2S)-2-[(4-methylbenzoyl)amino]-3-(4-phenylmethoxyphenyl)propanoate	Investigative	71452971	C25H25NO4	403.5	CC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OCC3=CC=CC=C3)C(=O)OC	IC50 > 1000000 nM	Non binder
T28887	Histone deacetylase 8	BH8UK5	4-Benzyloxy-n-methanesulfonyl-phenylalanine-methylester	Investigative	54185618	C18H21NO5S	363.4	COC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC=CC=C2)NS(=O)(=O)C	IC50 = 753700 nM	Non binder
T28887	Histone deacetylase 8	BI4C0G	Methyl (2S)-2-[(4-methylbenzoyl)amino]-3-[4-(2-phenylethoxy)phenyl]propanoate	Investigative	71449332	C26H27NO4	417.5	CC1=CC=C(C=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)OCCC3=CC=CC=C3)C(=O)OC	IC50 > 1000000 nM	Non binder
T28887	Histone deacetylase 8	BK0NI9	Methyl (2S)-2-[(4-methylphenyl)sulfonylamino]-3-(4-phenylmethoxyphenyl)propanoate	Investigative	67684770	C24H25NO5S	439.5	CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CC=C(C=C2)OCC3=CC=CC=C3)C(=O)OC	IC50 > 1000000 nM	Non binder
T28887	Histone deacetylase 8	BQM69W	(2S)-2-Benzamido-3-[4-(2-phenylethoxy)phenyl]propanoic acid	Investigative	71461881	C24H23NO4	389.4	C1=CC=C(C=C1)CCOC2=CC=C(C=C2)C[C@@H](C(=O)O)NC(=O)C3=CC=CC=C3	IC50 = 253400 nM	Non binder
T28887	Histone deacetylase 8	BQT2D7	N-Acetyl-O-benzyl-L-tyrosine methyl ester	Investigative	71452972	C19H21NO4	327.4	CC(=O)N[C@@H](CC1=CC=C(C=C1)OCC2=CC=CC=C2)C(=O)OC	IC50 = 871500 nM	Non binder