TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T29130 Signal transducer and activator of transcription 3 B3STW2 [4-[[4-[(4-Cyclohexylphenyl)carbamoyl]-2-naphthalen-1-yl-1,3-oxazol-5-yl]methyl]phenyl] dihydrogen phosphate Investigative 67325706 C33H31N2O6P 582.6 C1CCC(CC1)C2=CC=C(C=C2)NC(=O)C3=C(OC(=N3)C4=CC=CC5=CC=CC=C54)CC6=CC=C(C=C6)OP(=O)(O)O IC50 = 255000 nM Non binder T29130 Signal transducer and activator of transcription 3 B8IO3N 5-(N-Benzyl-2-(N,4-dimethylphenylsulfonamido)acetamido)-2-hydroxybenzoic acid Investigative 76322107 C24H24N2O6S 468.5 CC1=CC=C(C=C1)S(=O)(=O)N(C)CC(=O)N(CC2=CC=CC=C2)C3=CC(=C(C=C3)O)C(=O)O IC50 > 1000000 nM Non binder T29130 Signal transducer and activator of transcription 3 B8O4SB 2-(Benzo[d][1,3]dioxol-5-yl)-N-(3,4-dihydroxyphenethyl)acetamide Investigative 44580433 C17H17NO5 315.32 C1OC2=C(O1)C=C(C=C2)CC(=O)NCCC3=CC(=C(C=C3)O)O IC50 = 357000 nM Non binder T29130 Signal transducer and activator of transcription 3 B92SLT 2-Phenyl-5-[(4-phosphonooxyphenyl)methyl]-1,3-oxazole-4-carboxylic acid Investigative 91801280 C17H14NO7P 375.27 C1=CC=C(C=C1)C2=NC(=C(O2)CC3=CC=C(C=C3)OP(=O)(O)O)C(=O)O IC50 > 1000000 nM Non binder T29130 Signal transducer and activator of transcription 3 B94PQX N-(4-Cyclohexylphenyl)-5-[(4-hydroxyphenyl)methyl]-2-phenyl-1,3-oxazole-4-carboxamide Investigative 91801281 C29H28N2O3 452.5 C1CCC(CC1)C2=CC=C(C=C2)NC(=O)C3=C(OC(=N3)C4=CC=CC=C4)CC5=CC=C(C=C5)O IC50 > 1000000 nM Non binder T29130 Signal transducer and activator of transcription 3 BE8N9O 4-[(2S)-2-{[(1S)-1-(Benzylcarbamoyl)-3-methylbutyl]carbamoyl}-2-[(4-cyanophenyl)formamido]ethyl]phenoxyphosphonic acid Investigative 24768187 C30H33N4O7P 592.6 CC(C)C[C@@H](C(=O)NCC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=C(C=C2)OP(=O)(O)O)NC(=O)C3=CC=C(C=C3)C#N IC50 = 800000 nM Non binder T29130 Signal transducer and activator of transcription 3 BEI7T1 2-Hydroxy-4-[[2-[methyl-(4-methylphenyl)sulfonylamino]acetyl]amino]benzoic acid Investigative 73346330 C17H18N2O6S 378.4 CC1=CC=C(C=C1)S(=O)(=O)N(C)CC(=O)NC2=CC(=C(C=C2)C(=O)O)O IC50 > 300000 nM Non binder T29130 Signal transducer and activator of transcription 3 BK1R4J 4-[(2S)-2-[(4-Cyanophenyl)formamido]-2-{[(1S)-1-[(3-hydroxypropyl)carbamoyl]-3-methylbutyl]carbamoyl}ethyl]phenoxyphosphonic acid Investigative 24768184 C26H33N4O8P 560.5 CC(C)C[C@@H](C(=O)NCCCO)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)C2=CC=C(C=C2)C#N IC50 = 620000 nM Non binder T29130 Signal transducer and activator of transcription 3 BL1Y8W 5-[[2-[Benzyl-(4-phenylphenyl)sulfonylamino]acetyl]-[(4-piperidin-4-ylphenyl)methyl]amino]-2-hydroxybenzoic acid Investigative 76325718 C40H39N3O6S 689.8 C1CNCCC1C2=CC=C(C=C2)CN(C3=CC(=C(C=C3)O)C(=O)O)C(=O)CN(CC4=CC=CC=C4)S(=O)(=O)C5=CC=C(C=C5)C6=CC=CC=C6 IC50 > 300000 nM Non binder T29130 Signal transducer and activator of transcription 3 BLD04Z [4-[[4-[(4-Cyclohexylphenyl)carbamoyl]-2-phenyl-1,3-thiazol-5-yl]methyl]phenyl] dihydrogen phosphate Investigative 67326149 C29H29N2O5PS 548.6 C1CCC(CC1)C2=CC=C(C=C2)NC(=O)C3=C(SC(=N3)C4=CC=CC=C4)CC5=CC=C(C=C5)OP(=O)(O)O IC50 = 775000 nM Non binder T29130 Signal transducer and activator of transcription 3 BM2D4Q 2-Hydroxy-4-[[2-[(4-methylphenyl)sulfonylamino]acetyl]amino]benzoic acid Investigative 24785411 C16H16N2O6S 364.4 CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)NC2=CC(=C(C=C2)C(=O)O)O IC50 > 300000 nM Non binder T29130 Signal transducer and activator of transcription 3 BN5I9K 4-[(2S)-2-[(4-Cyanophenyl)formamido]-2-{[(1S)-3-methyl-1-(phenylcarbamoyl)butyl]carbamoyl}ethyl]phenoxyphosphonic acid Investigative 24768186 C29H31N4O7P 578.6 CC(C)C[C@@H](C(=O)NC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=C(C=C2)OP(=O)(O)O)NC(=O)C3=CC=C(C=C3)C#N IC50 = 310000 nM Non binder T29130 Signal transducer and activator of transcription 3 BO61RK Phaeosphaeride A Investigative 122195118 C15H23NO5 297.35 CCCCC[C@H]1[C@]([C@H](C2=C(O1)C(=C)N(C2=O)OC)O)(C)O IC50 = 610000 nM Non binder T29130 Signal transducer and activator of transcription 3 BST31M 2-Hydroxy-4-[[2-[(4-methylphenyl)sulfonyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetyl]amino]benzoic acid Investigative 68075871 C21H24N2O8S 464.5 CC1=CC=C(C=C1)S(=O)(=O)N(CC(=O)NC2=CC(=C(C=C2)C(=O)O)O)C(=O)OC(C)(C)C IC50 > 300000 nM Non binder T29130 Signal transducer and activator of transcription 3 BT10KR [4-[[4-[(4-Cyclohexylphenyl)carbamoyl]-2-naphthalen-1-yl-1,3-thiazol-5-yl]methyl]phenyl] dihydrogen phosphate Investigative 67326305 C33H31N2O5PS 598.6 C1CCC(CC1)C2=CC=C(C=C2)NC(=O)C3=C(SC(=N3)C4=CC=CC5=CC=CC=C54)CC6=CC=C(C=C6)OP(=O)(O)O IC50 = 350000 nM Non binder T29130 Signal transducer and activator of transcription 3 BVUX30 [4-[[4-(Hexylcarbamoyl)-2-phenyl-1,3-oxazol-5-yl]methyl]phenyl] dihydrogen phosphate Investigative 67387307 C23H27N2O6P 458.4 CCCCCCNC(=O)C1=C(OC(=N1)C2=CC=CC=C2)CC3=CC=C(C=C3)OP(=O)(O)O IC50 > 1000000 nM Non binder T29130 Signal transducer and activator of transcription 3 BZYR19 2-Hydroxy-5-[N-benzyl-N-(benzyl p-toluenesulfonylamino)acetylamino]benzoic acid Investigative 76336556 C30H28N2O6S 544.6 CC1=CC=C(C=C1)S(=O)(=O)N(CC2=CC=CC=C2)CC(=O)N(CC3=CC=CC=C3)C4=CC(=C(C=C4)O)C(=O)O IC50 = 201300 nM Non binder