TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T30803 Glutathione reductase D0Y3DN Flavonoid derivative 4 Patented 5280343 C15H10O7 302.23 C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O IC50 = 218000 nM Non binder T30803 Glutathione reductase B2MV8P Nitrobenzene Investigative 7416 C6H5NO2 123.11 C1=CC=C(C=C1)[N+](=O)[O-] Ki = 274100 nM Non binder T30803 Glutathione reductase B98WSG 1-(4-Chlorophenyl)-3-morpholin-4-ylpropan-1-one Investigative 723918 C13H16ClNO2 253.72 C1COCCN1CCC(=O)C2=CC=C(C=C2)Cl IC50 > 212000 nM Non binder T30803 Glutathione reductase BAU02I 3-(2-Chlorophenothiazin-10-yl)propyl-[(4-chlorophenyl)methyl]-dimethyl-ammonium Investigative 11798906 C24H25Cl2N2S+ 444.4 C[N+](C)(CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl)CC4=CC=C(C=C4)Cl Ki = 2200000 nM Non binder T30803 Glutathione reductase BHC23G N-(Cyclohexylmethyl)-N,N-dimethyl-3-(2-chloro-10H-phenothiazine-10-yl)propane-1-aminium Investigative 10791392 C24H32ClN2S+ 416 C[N+](C)(CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl)CC4CCCCC4 Ki = 2000000 nM Non binder T30803 Glutathione reductase BP0EU3 (E)-3-(3,4-Dihydroxy-phenyl)-N-[3-(4-{3-[(E)-3-(3,4-dihydroxy-phenyl)-acryloylamino]-propylamino}-butylamino)-propyl]-acrylamide Investigative 44315802 C28H38N4O6 526.6 C1=CC(=C(C=C1/C=C/C(=O)NCCCNCCCCNCCCNC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O Ki > 10000000 nM Non binder T30803 Glutathione reductase BRZX94 (2E,5E)-2,5-Bis[[4-(azidomethyl)phenyl]methylidene]cyclopentan-1-one Investigative 76317389 C21H18N6O 370.4 C1/C(=C\\C2=CC=C(C=C2)CN=[N+]=[N-])/C(=O)/C(=C/C3=CC=C(C=C3)CN=[N+]=[N-])/C1 IC50 = 228000 nM Non binder T30803 Glutathione reductase D0O2DQ Mepacrine Investigative 237 C23H30ClN3O 400 CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC IC50 > 1000000 nM Non binder