TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T31309	Apoptosis regulator Bcl-2	B4LRU2	2-[2-[(2S)-2-[(5Z)-5-[(4-Bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoyl]oxyethoxy]ethyl (2S)-2-[(5Z)-5-[(4-bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoate	Investigative	44456211	C42H34Br2N2O7S4	966.8	C1=CC=C(C=C1)C[C@H](N2C(=S)S/C(=C\\C3=CC=C(C=C3)Br)/C2=O)C(=O)OCCOCCOC(=O)[C@@H](N4C(=S)S/C(=C\\C5=CC=C(C=C5)Br)/C4=O)CC6=CC=CC=C6	Ki > 1000000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	B5VB1D	Ethyl (2S)-2-[(5Z)-5-[[4-[[4-[(Z)-[3-[(2S)-1-ethoxy-1-oxo-3-phenylpropan-2-yl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]phenoxy]methoxy]phenyl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoate	Investigative	44456176	C43H38N2O8S4	839	CCOC(=O)[C@@H](N1C(=S)S/C(=C\\C2=CC=C(C=C2)OCOC3=CC=C(C=C3)/C=C/4\\SC(=S)N(C4=O)[C@H](C(=O)OCC)CC5=CC=CC=C5)/C1=O)CC6=CC=CC=C6	Ki = 226000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	B69UQH	3,7-Dimethyl-benzofuran-2-carboxylic acid	Investigative	3163284	C11H10O3	190.19	CC1=C2C(=CC=C1)C(=C(O2)C(=O)O)C	Ki > 1000000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	B8MP9W	2-Propenyl 2-[5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]-3-phenylpropanoate	Investigative	44429180	C22H18BrNO3S2	488.4	C=CCOC(=O)[C@H](CC1=CC=CC=C1)N2C(=O)/C(=C/C3=CC=C(C=C3)Br)/SC2=S	Ki > 1000000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	B9KU5S	Ethyl (2S)-2-[(5Z)-5-[(4-bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoate	Investigative	44456125	C21H18BrNO3S2	476.4	CCOC(=O)[C@H](CC1=CC=CC=C1)N2C(=O)/C(=C/C3=CC=C(C=C3)Br)/SC2=S	Ki = 260000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	B9QLO8	3-Chloro-6-methylbenzo[b]thiophene-2-carboxylic acid	Investigative	815185	C10H7ClO2S	226.68	CC1=CC2=C(C=C1)C(=C(S2)C(=O)O)Cl	Ki > 1000000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	BFGE04	3-(1-Naphthylmethylsulfanyl)-1H-1,2,4-triazole	Investigative	719016	C13H11N3S	241.31	C1=CC=C2C(=C1)C=CC=C2CSC3=NC=NN3	Ki > 1000000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	BHL4S2	2-[5-(4-Bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]-glutaric acid	Investigative	26378673	C15H12BrNO5S2	430.3	C1=CC(=CC=C1/C=C\\2/C(=O)N(C(=S)S2)[C@@H](CCC(=O)O)C(=O)O)Br	Ki = 320000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	BI3FC4	3-(4-Chloro-3,5-dimethylphenoxy)propanoic acid	Investigative	22683787	C11H13ClO3	228.67	CC1=CC(=CC(=C1Cl)C)OCCC(=O)O	Ki > 1000000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	BLGA14	(4S)-4,8-Dihydroxy-3,4-dihydro-2H-naphthalen-1-one	Investigative	13369486	C10H10O3	178.18	C1CC(=O)C2=C([C@H]1O)C=CC=C2O	Ki = 474760 nM	Non binder
T31309	Apoptosis regulator Bcl-2	BMI47C	2-[(2S)-2-[(5Z)-5-[(4-Bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoyl]oxyethyl (2S)-2-[(5Z)-5-[(4-bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanoate	Investigative	44456210	C40H30Br2N2O6S4	922.8	C1=CC=C(C=C1)C[C@H](N2C(=S)S/C(=C\\C3=CC=C(C=C3)Br)/C2=O)C(=O)OCCOC(=O)[C@@H](N4C(=S)S/C(=C\\C5=CC=C(C=C5)Br)/C4=O)CC6=CC=CC=C6	Ki = 243000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	BN6X4G	7-Methyl-3-phenyl-1H-indole-2-carboxylic acid	Investigative	16645886	C16H13NO2	251.28	CC1=C2C(=CC=C1)C(=C(N2)C(=O)O)C3=CC=CC=C3	Ki > 1000000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	BU94MQ	5,6,7,8-Tetrahydro-1-naphthol	Investigative	68258	C10H12O	148.2	C1CCC2=C(C1)C=CC=C2O	IC50 = 4300000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	BU9D4O	3,6,7-Trimethyl-benzofuran-2-carboxylic acid	Investigative	6484626	C12H12O3	204.22	CC1=C(C2=C(C=C1)C(=C(O2)C(=O)O)C)C	Ki > 1000000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	BUFB14	(4-Chloro-3-methylphenoxy)acetic acid	Investigative	95696	C9H9ClO3	200.62	CC1=C(C=CC(=C1)OCC(=O)O)Cl	Ki > 1000000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	BZJ3W9	3,4-Dichloro-1-benzothiophene-2-carboxylic acid	Investigative	819258	C9H4Cl2O2S	247.1	C1=CC2=C(C(=C1)Cl)C(=C(S2)C(=O)O)Cl	Ki > 1000000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	BZNT67	Prop-2-enyl (2S)-2-(5-benzhydrylidene-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)-3-phenylpropanoate	Investigative	44429181	C28H23NO3S2	485.6	C=CCOC(=O)[C@H](CC1=CC=CC=C1)N2C(=O)C(=C(C3=CC=CC=C3)C4=CC=CC=C4)SC2=S	Ki = 260000 nM	Non binder
T31309	Apoptosis regulator Bcl-2	D0T3VP	4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID	Investigative	2782689	C13H9FO2	216.21	C1=CC(=CC=C1C2=CC=C(C=C2)F)C(=O)O	IC50 = 300000 nM	Non binder