TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit B08ZGC 2,5-Diethoxy-N-[3-(1H-imidazol-1-yl)propyl]benzenesulfonamide Investigative 15944053 C16H23N3O4S 353.4 CCOC1=CC(=C(C=C1)OCC)S(=O)(=O)NCCCN2C=CN=C2 IC50 > 200000 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit B1BIA9 Pyrrolopyridine, 9 Investigative 16719862 C18H15N3O 289.3 C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC=CC=C4 IC50 > 200000 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit B3X0ZT 7-Azaindole Investigative 9222 C7H6N2 118.14 C1=CC2=C(NC=C2)N=C1 IC50 > 630957.34 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit B63XVL 2,5-Diethoxy-N-[3-(1H-imidazol-1-yl)propyl]-4-methylbenzenesulfonamide Investigative 15944061 C17H25N3O4S 367.5 CCOC1=CC(=C(C=C1C)OCC)S(=O)(=O)NCCCN2C=CN=C2 IC50 > 200000 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit B78NRQ Chembl4278680 Investigative 145982087 C16H20N2O4S 336.4 CCN1C2=CC=C(C3=CC=CC(C32)C1=O)S(=O)(=O)NCCCO IC50 > 200000 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit B98LVP Chembl4292106 Investigative 145986473 C11H15Cl2NO4S 328.2 CCOC1=C(C=CC(=C1Cl)Cl)S(=O)(=O)NCC(C)O IC50 > 200000 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit BATG37 7-Methoxy-3,4,5,10-tetrahydro-1H-2,5-methanoazepino[3,4-b]indole-1-carboxylic Acid Investigative 23661564 C15H16N2O3 272.3 COC1=CC2=C(C=C1)NC3=C2C4CCN(C4)C3C(=O)O IC50 > 200000 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit BEW6F7 2-[2-(2-Fluorophenyl)pyridin-4-yl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one Investigative 11992146 C18H14FN3O 307.3 C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC=CC=C4F IC50 > 200000 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit BGS51N 6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-1-carboxylic acid Investigative 3848929 C13H14N2O3 246.26 COC1=CC2=C(C=C1)NC3=C2CCNC3C(=O)O IC50 > 200000 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit BH4BV1 N-Phenylpyrimidin-2-amine Investigative 11643997 C10H9N3 171.2 C1=CC=C(C=C1)NC2=NC=CC=N2 IC50 > 630957.34 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit BO4KT1 Chembl4285936 Investigative 145993087 C19H19N3O5S2 433.5 CCN1C2=CC=C(C3=CC=CC(C32)C1=O)S(=O)(=O)NC4=CC(=CC=C4)S(=O)(=O)N IC50 > 200000 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit BOG57Q Chembl4281480 Investigative 145979715 C12H17Cl2NO4S 342.2 CCC(CO)NS(=O)(=O)C1=C(C(=C(C=C1)Cl)Cl)OCC IC50 > 200000 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit BT6L2H 4-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-ylamino)-benzenesulfonamide Investigative 11559659 C19H18N4O2S 366.4 C1CC2=CC=CC=C2C3=NC(=NC=C3C1)NC4=CC=C(C=C4)S(=O)(=O)N IC50 > 10000000 nM Non binder T32335 Inhibitor of nuclear factor kappa-B kinase beta subunit D0EW9J PMID17480064C16 Investigative 10389239 C21H16N4O 340.4 C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC5=CC=CC=C5N=C4 IC50 > 200000 nM Non binder