TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T37541 Carbonic anhydrase VII D02PJA Hydriodic acid iodine-125 Approved 24841 HI 127.912 I Ki = 250000 nM Non binder T37541 Carbonic anhydrase VII D03UOT Hydroquinone Approved 785 C6H6O2 110.11 C1=CC(=CC=C1O)O Ki = 883000 nM Non binder T37541 Carbonic anhydrase VII D0OT0O Foscavir Approved 44561 CNa3O5P 191.95 C(=O)([O-])P(=O)([O-])[O-].[Na+].[Na+].[Na+] Ki = 560000 nM Non binder T37541 Carbonic anhydrase VII D0L6HN PHENOL Phase 2/3 996 C6H6O 94.11 C1=CC=C(C=C1)O Ki > 500000 nM Non binder T37541 Carbonic anhydrase VII B05AXZ Sodium diethyldithiocarbamate Investigative 533728 C5H10NNaS2 171.3 CCN(CC)C(=S)[S-].[Na+] Ki = 1470000 nM Non binder T37541 Carbonic anhydrase VII B0VI1Y N-(Dipropylsulfamoyl)-N-propylpropan-1-amine Investigative 44424363 C12H28N2O2S 264.43 CCCN(CCC)S(=O)(=O)N(CCC)CCC Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII B2MK1G Di-tert-butylethane-1,2-diylbis(2-(2,2,2-trifluoroacetamido)ethylcarbamate Investigative 12066940 C20H32F6N4O6 538.5 CC(C)(C)OC(=O)N(CCNC(=O)C(F)(F)F)CCN(CCNC(=O)C(F)(F)F)C(=O)OC(C)(C)C Ki > 500000 nM Non binder T37541 Carbonic anhydrase VII B2RG5L N-(N-Boc-sulfamoyl)glycine Methyl Ester Investigative 44590306 C8H16N2O6S 268.29 CC(C)(C)OC(=O)NS(=O)(=O)NCC(=O)OC Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII B3CF2B Methyl 3-(Butylsulfamoylamino)Propanoate Investigative 25258363 C8H18N2O4S 238.31 CCCCNS(=O)(=O)NCCC(=O)OC Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII B3W7GJ Hydrazoic acid Investigative 24530 HN3 43.029 N=[N+]=[N-] Ki = 1410000 nM Non binder T37541 Carbonic anhydrase VII B6E1XO Di-tert-butylpropane-1,3-diylbis(2-(2,2,2-trifluoroacetamido)-ethylcarbamate Investigative 12066941 C21H34F6N4O6 552.5 CC(C)(C)OC(=O)N(CCCN(CCNC(=O)C(F)(F)F)C(=O)OC(C)(C)C)CCNC(=O)C(F)(F)F Ki > 500000 nM Non binder T37541 Carbonic anhydrase VII B71NEW N,N,N',N'-Tetrabutylsulfamide Investigative 44424364 C16H36N2O2S 320.5 CCCCN(CCCC)S(=O)(=O)N(CCCC)CCCC Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII B72KYJ Hydrofluoric acid Investigative 14917 FH 20.006 F Ki = 1240000 nM Non binder T37541 Carbonic anhydrase VII B74DBN Hydrogen sulfide Investigative 402 H2S 34.08 S Ki = 1240000 nM Non binder T37541 Carbonic anhydrase VII B9PUL1 (2S)-2-[[(Tert-Butyloxycarbonyl)sulfamoyl]amino]propionic acid methyl ester Investigative 15014351 C9H18N2O6S 282.32 C[C@@H](C(=O)OC)NS(=O)(=O)NC(=O)OC(C)(C)C Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII BA1HF6 Sodium selenocyanate Investigative 13927398 CNNaSe 127.98 C(#N)[Se-].[Na+] Ki = 1100000 nM Non binder T37541 Carbonic anhydrase VII BC2WH9 Sulfurous acid Investigative 1100 H2O3S 82.08 OS(=O)O Ki = 7300000 nM Non binder T37541 Carbonic anhydrase VII BC6XN1 Hydrogen bromide Investigative 260 BrH 80.91 Br Ki = 1060000 nM Non binder T37541 Carbonic anhydrase VII BCHB47 Sulfuric acid Investigative 1118 H2O4S 98.08 OS(=O)(=O)O Ki = 1380000 nM Non binder T37541 Carbonic anhydrase VII BCY10H Methyl 3-[[(2-methylpropan-2-yl)oxycarbonyl-(2-propylpentyl)sulfamoyl]amino]propanoate Investigative 25258361 C17H34N2O6S 394.5 CCCC(CCC)CN(C(=O)OC(C)(C)C)S(=O)(=O)NCCC(=O)OC Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII BE3GW2 Cyanic acid Investigative 540 CHNO 43.025 C(#N)O Ki = 15200000 nM Non binder T37541 Carbonic anhydrase VII BEH8D0 Hydrogen cyanide Investigative 768 CHN 27.025 C#N Ki = 9200000 nM Non binder T37541 Carbonic anhydrase VII BFNJ79 2-Hydroxycinnamic acid Investigative 637540 C9H8O3 164.16 C1=CC=C(C(=C1)/C=C/C(=O)O)O Ki > 1000000 nM Non binder T37541 Carbonic anhydrase VII BGSX45 Nitrous acid Investigative 24529 HNO2 47.014 N(=O)O Ki = 1780000 nM Non binder T37541 Carbonic anhydrase VII BIKB27 N,N'-Dipropylsulfamide Investigative 15729847 C6H16N2O2S 180.27 CCCNS(=O)(=O)NCCC Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII BIYO50 N,N'-Sulfonyl Bis-L-alanine Dimethyl Ester Investigative 18710120 C8H16N2O6S 268.29 C[C@@H](C(=O)OC)NS(=O)(=O)N[C@@H](C)C(=O)OC Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII BM35ZE 2-Phenyl-N-(2-phenylethylsulfamoyl)ethanamine Investigative 14787919 C16H20N2O2S 304.4 C1=CC=C(C=C1)CCNS(=O)(=O)NCCC2=CC=CC=C2 Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII BM8Z9E Methyl 3-[(3-methoxy-3-oxopropyl)sulfamoylamino]propanoate Investigative 25258360 C8H16N2O6S 268.29 COC(=O)CCNS(=O)(=O)NCCC(=O)OC Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII BRMA78 Dioxido(oxo)tin Investigative 25502 O3Sn-2 166.71 [O-][Sn](=O)[O-] Ki = 670000 nM Non binder T37541 Carbonic anhydrase VII BTN45D N,N'-Sulfonyl Bis-L-valine Dimethyl Ester Investigative 12051191 C12H24N2O6S 324.4 CC(C)[C@@H](C(=O)OC)NS(=O)(=O)N[C@@H](C(C)C)C(=O)OC Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII BUW28P Sodium pyrovanadate(V) Investigative 4608376 O7V2-4 213.88 [O-][V](=O)([O-])O[V](=O)([O-])[O-] Ki = 600000 nM Non binder T37541 Carbonic anhydrase VII BW81UM 4-Hydroxybenzoic acid Investigative 135 C7H6O3 138.12 C1=CC(=CC=C1C(=O)O)O Ki = 716000 nM Non binder T37541 Carbonic anhydrase VII BWS8H6 Perrhenate Investigative 139584 O4Re- 250.2 [O-][Re](=O)(=O)=O Ki = 36540000 nM Non binder T37541 Carbonic anhydrase VII BZ18TA N1,N2-(2-(2,2,2-Trifluoroacetamido)ethyl)ethane-1,2-diaminium Trifluoroacetate Investigative 15938557 C10H16F6N4O2 338.25 C(CNCCNC(=O)C(F)(F)F)NCCNC(=O)C(F)(F)F Ki > 500000 nM Non binder T37541 Carbonic anhydrase VII BZYH06 1-[Propyl(Sulfamoyl)Amino]Propane Investigative 20184392 C6H16N2O2S 180.27 CCCN(CCC)S(=O)(=O)N Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII D00IUB 4-CYANOPHENOL Investigative 13019 C7H5NO 119.12 C1=CC(=CC=C1C#N)O Ki = 777000 nM Non binder T37541 Carbonic anhydrase VII D01BUB 2,5-difluorophenol Investigative 94952 C6H4F2O 130.09 C1=CC(=C(C=C1F)O)F Ki = 554000 nM Non binder T37541 Carbonic anhydrase VII D02DBP RESORCINOL Investigative 5054 C6H6O2 110.11 C1=CC(=CC(=C1)O)O Ki = 644000 nM Non binder T37541 Carbonic anhydrase VII D03ZMQ COUMARIN Investigative 323 C9H6O2 146.14 C1=CC=C2C(=C1)C=CC(=O)O2 Ki > 200000 nM Non binder T37541 Carbonic anhydrase VII D07MTM 4-AMINOPHENOL Investigative 403 C6H7NO 109.13 C1=CC(=CC=C1N)O Ki = 1359000 nM Non binder T37541 Carbonic anhydrase VII D07QJJ CATECHOL Investigative 289 C6H6O2 110.11 C1=CC=C(C(=C1)O)O Ki = 714000 nM Non binder T37541 Carbonic anhydrase VII D0C7LR LLZ16406 Investigative 313 ClH 36.46 Cl Ki = 1840000 nM Non binder T37541 Carbonic anhydrase VII D0D5XC Sodium trithiocarbonate Investigative 101753 CNa2S3 154.2 C(=S)([S-])[S-].[Na+].[Na+] Ki = 36150000 nM Non binder