TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T39321	Glyceraldehyde-3-phosphate dehydrogenase	D0NQ5I	METRIFUDIL	Terminated	65710	C18H21N5O4	371.4	CC1=CC=CC=C1CNC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O	IC50 = 700000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B0C7ZI	8-(2-Thienyl)-2'-[benzoylamino]-2'-deoxyadenosine	Investigative	10049523	C21H20N6O4S	452.5	C1=CC=C(C=C1)C(=O)N[C@@H]2[C@@H]([C@H](O[C@H]2N3C(=NC4=C(N=CN=C43)N)C5=CC=CS5)CO)O	IC50 = 500000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B12JWN	N-[(2R,3R,4S,5R)-2-(6-Aminopurin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-3-methoxybenzamide	Investigative	467916	C18H20N6O5	400.4	COC1=CC=CC(=C1)C(=O)N[C@@H]2[C@@H]([C@H](O[C@H]2N3C=NC4=C(N=CN=C43)N)CO)O	IC50 = 300000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B2E6XT	Chembl604351	Investigative	10834615	C20H23N5O4	397.4	C1CC(C2=CC=CC=C2C1)NC3=C4C(=NC=N3)N(C=N4)[C@H]5[C@@H]([C@@H]([C@H](O5)CO)O)O	IC50 = 360000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B2KS7F	2'-[(3-Ethoxybenzoyl)amino]-2'-deoxyadenosine	Investigative	10319600	C19H22N6O5	414.4	CCOC1=CC=CC(=C1)C(=O)N[C@@H]2[C@@H]([C@H](O[C@H]2N3C=NC4=C(N=CN=C43)N)CO)O	IC50 = 400000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B2WKX6	2'-[(Quinolin-7-ylcarbonyl)amino]-2'-deoxyadenosine	Investigative	10454854	C20H19N7O4	421.4	C1=CC2=C(C=C(C=C2)C(=O)N[C@@H]3[C@@H]([C@H](O[C@H]3N4C=NC5=C(N=CN=C54)N)CO)O)N=C1	IC50 = 500000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B2X9NT	(2R,3S,4R)-2-(Hydroxymethyl)-5-[6-[(4-hydroxy-3-methylbutyl)amino]purin-9-yl]oxolane-3,4-diol	Investigative	9924682	C15H23N5O5	353.37	CC(CCNC1=C2C(=NC=N1)N(C=N2)C3[C@@H]([C@@H]([C@H](O3)CO)O)O)CO	IC50 = 34003000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B30LGC	2'-[(3,5-Dihydroxybenzoyl)amino]-2'-deoxyadenosine	Investigative	10668788	C17H18N6O6	402.4	C1=C(C=C(C=C1O)O)C(=O)N[C@@H]2[C@@H]([C@H](O[C@H]2N3C=NC4=C(N=CN=C43)N)CO)O	IC50 = 650000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B34QIN	2'-[(3-Methoxy-4-hydroxybenzoyl)amino]-2'-deoxyadenosine	Investigative	10835695	C18H20N6O6	416.4	COC1=C(C=CC(=C1)C(=O)N[C@@H]2[C@@H]([C@H](O[C@H]2N3C=NC4=C(N=CN=C43)N)CO)O)O	IC50 = 500000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B3MRP2	(2R,3S,4R)-2-(Hydroxymethyl)-5-[6-[[2-[2-(hydroxymethyl)phenyl]sulfanylphenyl]methylamino]purin-9-yl]oxolane-3,4-diol	Investigative	46876205	C24H25N5O5S	495.6	C1=CC=C(C(=C1)CNC2=C3C(=NC=N2)N(C=N3)C4[C@@H]([C@@H]([C@H](O4)CO)O)O)SC5=CC=CC=C5CO	IC50 = 340000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B4MR1U	4-Methoxy-2,3-dihydrofuro[3,2-g]chromen-7-one	Investigative	21829325	C12H10O4	218.2	COC1=C2C=CC(=O)OC2=CC3=C1CCO3	IC50 = 346736.85 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B4WAG1	(3R,4S,5R)-2-(6-Amino-8-cyclohexylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol	Investigative	46875585	C16H23N5O4S	381.5	C1CCC(CC1)SC2=NC3=C(N=CN=C3N2C4[C@@H]([C@@H]([C@H](O4)CO)O)O)N	IC50 > 1000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B52BHX	N-[(1R,2R)-2-(6-Amino-purin-9-yl)-cyclopentyl]-3-chloro-benzamide	Investigative	10360939	C17H17ClN6O	356.8	C1C[C@H]([C@@H](C1)N2C=NC3=C(N=CN=C32)N)NC(=O)C4=CC(=CC=C4)Cl	IC50 > 2000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B5PAQ6	Adenosine, 8-(2-thienyl)-	Investigative	10066396	C14H15N5O4S	349.37	C1=CSC(=C1)C2=NC3=C(N=CN=C3N2[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)N	Ki = 300000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B5W2NS	(3R,4S,5R)-2-[6-(Benzhydrylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol	Investigative	46874050	C23H23N5O4	433.5	C1=CC=C(C=C1)C(C2=CC=CC=C2)NC3=C4C(=NC=N3)N(C=N4)C5[C@@H]([C@@H]([C@H](O5)CO)O)O	IC50 = 240000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B6JHX0	N-[2-(6-Amino-purin-9-yl)-ethyl]-3-chloro-benzamide	Investigative	10381084	C14H13ClN6O	316.74	C1=CC(=CC(=C1)Cl)C(=O)NCCN2C=NC3=C(N=CN=C32)N	IC50 > 4000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B7CMG3	N-[(2R,3R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)-2-[6-(2-methylpropanoylamino)purin-9-yl]oxolan-3-yl]-3-methoxybenzamide	Investigative	10528348	C22H26N6O6	470.5	CC(C)C(=O)NC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)NC(=O)C4=CC(=CC=C4)OC	IC50 = 1200000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B7E5JP	(2R,3S,4R)-2-(Hydroxymethyl)-5-[6-(2-methylbutylamino)purin-9-yl]oxolane-3,4-diol	Investigative	46876222	C15H23N5O4	337.37	CCC(C)CNC1=C2C(=NC=N1)N(C=N2)C3[C@@H]([C@@H]([C@H](O3)CO)O)O	IC50 > 5400000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B7M3SH	(3R,4S,5R)-2-[6-Amino-8-(propan-2-ylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol	Investigative	46876011	C13H20N6O4	324.34	CC(C)NC1=NC2=C(N=CN=C2N1C3[C@@H]([C@@H]([C@H](O3)CO)O)O)N	Ki = 1500000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B7UY0A	2-[[(2R,3S,4R)-5-[6-(Benzylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl]isoindole-1,3-dione	Investigative	46875985	C25H22N6O5	486.5	C1=CC=C(C=C1)CNC2=C3C(=NC=N2)N(C=N3)C4[C@@H]([C@@H]([C@H](O4)CN5C(=O)C6=CC=CC=C6C5=O)O)O	Ki = 4000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B7W0UV	N-Isopentyladenosine	Investigative	87216	C15H23N5O4	337.37	CC(C)CCNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O	IC50 = 3700000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B94LBC	(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-[6-(m-tolylmethylamino)purin-9-yl]tetrahydrofuran-3,4-diol	Investigative	10339188	C18H21N5O4	371.4	CC1=CC(=CC=C1)CNC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O	IC50 = 700000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	B94UOA	N-[(1R,2R)-2-(6-Amino-purin-9-yl)-cyclopentyl]-3-methoxy-benzamide	Investigative	10450657	C18H20N6O2	352.4	COC1=CC=CC(=C1)C(=O)N[C@@H]2CCC[C@H]2N3C=NC4=C(N=CN=C43)N	IC50 > 4000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BA0U5G	N-[(1R,2R)-2-(6-Amino-purin-9-yl)-cyclopentyl]-3-bromo-benzamide	Investigative	10318843	C17H17BrN6O	401.3	C1C[C@H]([C@@H](C1)N2C=NC3=C(N=CN=C32)N)NC(=O)C4=CC(=CC=C4)Br	IC50 = 700000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BA58FL	9-(2-Benzylamino-ethyl)-8-thiophen-2-yl-9H-purin-6-ylamine	Investigative	9975183	C18H18N6S	350.4	C1=CC=C(C=C1)CNCCN2C(=NC3=C(N=CN=C32)N)C4=CC=CS4	IC50 = 400000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BB9HC1	NAD+ analogue	Investigative	118719207	C39H40N8O15P2	922.7	COC1=CC=CC(=C1)C(=O)N[C@@H]2[C@@H]([C@H](O[C@H]2N3C=NC4=C(N=CN=C43)NCC5=CC=CC6=CC=CC=C65)COP(=O)(O)OP(=O)([O-])O[C@@H]7[C@H]([C@H]([C@@H](O7)[N+]8=CC=CC(=C8)C(=O)N)O)O)O	IC50 > 500000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BF23NM	(3R,4S,5R)-2-(6-Amino-8-pyrimidin-2-ylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol	Investigative	46876082	C14H15N7O4S	377.38	C1=CN=C(N=C1)SC2=NC3=C(N=CN=C3N2C4[C@@H]([C@@H]([C@H](O4)CO)O)O)N	IC50 = 2000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BFA5C4	N-[2-(6-Amino-purin-9-yl)-ethyl]-3-fluoro-benzamide	Investigative	10334943	C14H13FN6O	300.29	C1=CC(=CC(=C1)F)C(=O)NCCN2C=NC3=C(N=CN=C32)N	IC50 > 4000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BGO9P1	8-(Thiophen-2-yl)-9-(2-aminoethyl)-9H-purin-6-amine	Investigative	10445321	C11H12N6S	260.32	C1=CSC(=C1)C2=NC3=C(N=CN=C3N2CCN)N	IC50 = 1600000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BHI76P	N-[2-(6-Amino-purin-9-yl)-ethyl]-4-methyl-benzamide	Investigative	10469836	C15H16N6O	296.33	CC1=CC=C(C=C1)C(=O)NCCN2C=NC3=C(N=CN=C32)N	IC50 > 2000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BICK14	2'-[Benzylamino]-2'-deoxyadenosine	Investigative	10428340	C17H20N6O3	356.4	C1=CC=C(C=C1)CN[C@@H]2[C@@H]([C@H](O[C@H]2N3C=NC4=C(N=CN=C43)N)CO)O	IC50 > 10000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BJ9VS3	N-[[(2R,3S,4R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-2,2-diphenylacetamide	Investigative	46875344	C24H24N6O4	460.5	C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC[C@@H]3[C@H]([C@H](C(O3)N4C=NC5=C(N=CN=C54)N)O)O	IC50 = 250000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BK10TC	8-Bromo-2'-[benzoylamino]-2'-deoxyadenosine	Investigative	10343681	C17H17BrN6O4	449.3	C1=CC=C(C=C1)C(=O)N[C@@H]2[C@@H]([C@H](O[C@H]2N3C4=NC=NC(=C4N=C3Br)N)CO)O	IC50 = 3000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BK20RG	2'-[(Isobutoxycarbonyl)amino]-2'-deoxyadenosine	Investigative	9998966	C15H22N6O5	366.37	CC(C)COC(=O)N[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)CO)O	IC50 > 10000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BM7B2R	2'-[(3-Hydroxybenzoyl)amino]-2'-deoxyadenosine	Investigative	10620158	C17H18N6O5	386.4	C1=CC(=CC(=C1)O)C(=O)N[C@@H]2[C@@H]([C@H](O[C@H]2N3C=NC4=C(N=CN=C43)N)CO)O	IC50 = 850000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BNA5K7	2-Methyl-2'-[(3-methoxybenzoyl)amino]-2'-deoxyadenosine	Investigative	10431926	C19H22N6O5	414.4	CC1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)NC(=O)C4=CC(=CC=C4)OC)N	IC50 > 10000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BO28EG	N6-Benzyladenosine	Investigative	92208	C17H19N5O4	357.4	C1=CC=C(C=C1)CNC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O	Ki = 2800000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BPJX60	8-Methoxy-2'-[benzoylamino]-2'-deoxyadenosine	Investigative	10408674	C18H20N6O5	400.4	COC1=NC2=C(N=CN=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)NC(=O)C4=CC=CC=C4)N	IC50 = 9000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BQ2IF8	N-[[(2R,3S,4R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]benzamide	Investigative	46876048	C17H18N6O4	370.4	C1=CC=C(C=C1)C(=O)NC[C@@H]2[C@H]([C@H](C(O2)N3C=NC4=C(N=CN=C43)N)O)O	Ki = 3300000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BQGH08	2-Methyladenine	Investigative	15048	C6H7N5	149.15	CC1=NC(=C2C(=N1)N=CN2)N	IC50 = 6000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BQI68R	2-N-[[(2R,3S,4R)-5-[6-(Benzylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl]benzene-1,2-dicarboxamide	Investigative	46876042	C25H25N7O5	503.5	C1=CC=C(C=C1)CNC2=C3C(=NC=N2)N(C=N3)C4[C@@H]([C@@H]([C@H](O4)CNC(=O)C5=CC=CC=C5C(=O)N)O)O	Ki = 800000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BR03SA	N-[[(2R,3S,4R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-4-(4-ethylphenyl)benzamide	Investigative	46875590	C25H26N6O4	474.5	CCC1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)NC[C@@H]3[C@H]([C@H](C(O3)N4C=NC5=C(N=CN=C54)N)O)O	IC50 = 750000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BT6J2E	Nicotinamide mononucleotide	Investigative	14180	C11H15N2O8P	334.22	C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)[O-])O)O)C(=O)N	IC50 > 500000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BV5L1H	(2R,3R,4S,5R)-2-[6-(Cycloheptylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol	Investigative	463722	C17H25N5O4	363.4	C1CCCC(CC1)NC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O	IC50 = 1800000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BW8Q3K	Riboprine	Investigative	24405	C15H21N5O4	335.36	CC(=CCNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)C	IC50 > 5000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BWT05R	N-[(4-Aminophenyl)methyl]adenosine	Investigative	125347	C17H20N6O4	372.4	C1=CC(=CC=C1CNC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)N	IC50 = 3100000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BX2AB4	2'-[(3,4,5-Trihydroxybenzoyl)amino]-2'-deoxyadenosine	Investigative	10740715	C17H18N6O7	418.4	C1=C(C=C(C(=C1O)O)O)C(=O)N[C@@H]2[C@@H]([C@H](O[C@H]2N3C=NC4=C(N=CN=C43)N)CO)O	IC50 = 250000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BX40TI	N-(2-Methylbenzyl)-2'-[(3-methoxybenzoyl)amino]-2'-deoxyadenosine	Investigative	10029114	C26H28N6O5	504.5	CC1=CC=CC=C1CNC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)NC(=O)C5=CC(=CC=C5)OC	IC50 > 270000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BXJ29O	2'-[(2-Hydroxy-3-methoxybenzoyl)amino]-2'-deoxyadenosine	Investigative	10549805	C18H20N6O6	416.4	COC1=CC=CC(=C1O)C(=O)N[C@@H]2[C@@H]([C@H](O[C@H]2N3C=NC4=C(N=CN=C43)N)CO)O	IC50 = 600000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BY53SZ	2'-[(1H-Benzimidazol-5-ylcarbonyl)amino]-2'-deoxyadenosine	Investigative	10341490	C18H18N8O4	410.4	C1=CC2=C(C=C1C(=O)N[C@@H]3[C@@H]([C@H](O[C@H]3N4C=NC5=C(N=CN=C54)N)CO)O)NC=N2	IC50 = 3000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BY68CN	Osthole	Investigative	10228	C15H16O3	244.28	CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C	IC50 = 208929.61 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	BZAN01	N-[(1R,2R)-2-(6-Amino-purin-9-yl)-cyclopentyl]-benzamide	Investigative	10019035	C17H18N6O	322.4	C1C[C@H]([C@@H](C1)N2C=NC3=C(N=CN=C32)N)NC(=O)C4=CC=CC=C4	IC50 > 4000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	D02JEZ	7-hydroxycoumarin	Investigative	5281426	C9H6O3	162.14	C1=CC(=CC2=C1C=CC(=O)O2)O	IC50 = 616595 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	D03RFA	N6-CYCLOPENTYLADENOSINE	Investigative	657378	C15H21N5O4	335.36	C1CCC(C1)NC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O	IC50 > 5000000 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	D03ZMQ	COUMARIN	Investigative	323	C9H6O2	146.14	C1=CC=C2C(=C1)C=CC(=O)O2	IC50 = 691830.97 nM	Non binder
T39321	Glyceraldehyde-3-phosphate dehydrogenase	D05QOR	SCOPOLETIN	Investigative	5280460	C10H8O4	192.17	COC1=C(C=C2C(=C1)C=CC(=O)O2)O	IC50 = 257039.58 nM	Non binder