TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T40016 Glucocorticoid receptor D0G3SH Ursodeoxycholic acid Approved 31401 C24H40O4 392.6 C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C EC50 = 298700 nM Non binder T40016 Glucocorticoid receptor B6V1CT (9R,10S,11S,13S,16R,17R)-17-(2-Bromoacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one Investigative 44294670 C22H28BrFO4 455.4 C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CBr)O)C)O)F)C EC50 = 8300000000 nM Non binder T40016 Glucocorticoid receptor BG92XC (9R,10S,11S,13S,16R,17R)-9-Fluoro-11,17-dihydroxy-17-[2-(2-isothiocyanatoethylsulfanyl)acetyl]-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one Investigative 44294768 C25H32FNO4S2 493.7 C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CSCCN=C=S)O)C)O)F)C EC50 = 9100000000 nM Non binder