TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T43332	Coagulation factor VII	B1TI5N	2-(1H-Imidazol-4-yl)-1H-benzoimidazole-5-carboxamidine	Investigative	22125586	C11H10N6	226.24	C1=CC2=C(C=C1C(=N)N)NC(=N2)C3=CN=CN3	Ki = 370000 nM	Non binder
T43332	Coagulation factor VII	B2NC1J	2-(1H-Benzo[d]imidazol-2-yl)-1H-benzo[d]imidazole-5-carboxamidine	Investigative	44407625	C15H12N6	276.3	C1=CC=C2C(=C1)NC(=N2)C3=NC4=C(N3)C=C(C=C4)C(=N)N	Ki = 440000 nM	Non binder
T43332	Coagulation factor VII	B3KQ2O	(2S)-2-[[(2S)-2-(Benzylsulfonylamino)-3-phenylpropanoyl]amino]-N-[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]-4-methylpentanamide	Investigative	56666511	C36H48N6O5S	676.9	CC(C)C[C@@H](C(=O)N[C@@H](CCCCN=C(N)N)C(=O)CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=CC=C2)NS(=O)(=O)CC3=CC=CC=C3	IC50 > 580000 nM	Non binder
T43332	Coagulation factor VII	B8EUF5	(2S)-2-[[(2R)-2-(Benzylsulfonylamino)-3-phenylpropanoyl]amino]-N-[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]-3-phenylpropanamide	Investigative	56680051	C39H46N6O5S	710.9	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CCCCN=C(N)N)C(=O)CC2=CC=CC=C2)NC(=O)[C@@H](CC3=CC=CC=C3)NS(=O)(=O)CC4=CC=CC=C4	IC50 = 640000 nM	Non binder
T43332	Coagulation factor VII	B8IBT4	N-[3-[(2-Fluorophenyl)methoxy]phenyl]-1-pyridin-4-ylpiperidine-4-carboxamide	Investigative	72712051	C24H24FN3O2	405.5	C1CN(CCC1C(=O)NC2=CC(=CC=C2)OCC3=CC=CC=C3F)C4=CC=NC=C4	Ki > 250000 nM	Non binder
T43332	Coagulation factor VII	BAX24N	(2S,3R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-N-[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]-3-hydroxybutanamide	Investigative	56676739	C27H38N6O5	526.6	C[C@H]([C@@H](C(=O)N[C@@H](CCCCN=C(N)N)C(=O)CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=C(C=C2)O)N)O	IC50 > 1340000 nM	Non binder
T43332	Coagulation factor VII	BC7F8S	(2S)-2-Acetamido-N-[(2S)-1-[[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]-3-phenylpropanamide	Investigative	56676740	C34H42N6O4	598.7	CC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCCN=C(N)N)C(=O)CC3=CC=CC=C3	IC50 > 400000 nM	Non binder
T43332	Coagulation factor VII	BENX24	N-[3-[(3,5-Difluorophenyl)methoxy]phenyl]-1-pyridin-4-ylpiperidine-4-carboxamide	Investigative	72712053	C24H23F2N3O2	423.5	C1CN(CCC1C(=O)NC2=CC(=CC=C2)OCC3=CC(=CC(=C3)F)F)C4=CC=NC=C4	Ki > 250000 nM	Non binder
T43332	Coagulation factor VII	BJ4XD5	N-[3-[(4-Fluorophenyl)methoxy]phenyl]-1-pyridin-4-ylpiperidine-4-carboxamide	Investigative	72712049	C24H24FN3O2	405.5	C1CN(CCC1C(=O)NC2=CC(=CC=C2)OCC3=CC=C(C=C3)F)C4=CC=NC=C4	Ki > 250000 nM	Non binder
T43332	Coagulation factor VII	BR1WS2	(2S)-2-Amino-N-[(2S)-1-[[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]-3-phenylpropanamide	Investigative	56673432	C32H40N6O3	556.7	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCCN=C(N)N)C(=O)CC3=CC=CC=C3)N	IC50 > 1480000 nM	Non binder
T43332	Coagulation factor VII	BTN7H0	N-[3-(3-Fluorobenzyloxy)phenyl]-1-(4-pyridinyl)piperidine-4-carboxamide	Investigative	72712050	C24H24FN3O2	405.5	C1CN(CCC1C(=O)NC2=CC(=CC=C2)OCC3=CC(=CC=C3)F)C4=CC=NC=C4	Ki > 250000 nM	Non binder
T43332	Coagulation factor VII	BVS04D	(3R)-2-[2-(4-Chlorophenyl)acetyl]-N-[4-(3-oxomorpholin-4-yl)phenyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	Investigative	66573845	C28H26ClN3O4	504	C1COCC(=O)N1C2=CC=C(C=C2)NC(=O)[C@H]3CC4=CC=CC=C4CN3C(=O)CC5=CC=C(C=C5)Cl	IC50 > 1000000 nM	Non binder
T43332	Coagulation factor VII	BWCR37	(2S,3R)-2-[[(2S)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-N-[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]-3-hydroxybutanamide	Investigative	56659587	C29H40N6O6	568.7	C[C@H]([C@@H](C(=O)N[C@@H](CCCCN=C(N)N)C(=O)CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)C)O	IC50 > 1340000 nM	Non binder
T43332	Coagulation factor VII	BZB3C9	N-[3-[(3,4-Dimethoxyphenyl)methoxy]phenyl]-1-pyridin-4-ylpiperidine-4-carboxamide	Investigative	72712070	C26H29N3O4	447.5	COC1=C(C=C(C=C1)COC2=CC=CC(=C2)NC(=O)C3CCN(CC3)C4=CC=NC=C4)OC	Ki > 250000 nM	Non binder